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Product Details
PA5-77056
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human CTNS.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2720783
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cystinosin; cystinosis nephropathic; cystinosis, nephropathic
Gene Aliases: AI195360; AW049661; CTNS; CTNS-LSB; PQLC4
UniProt ID: (Human) O60931, (Mouse) P57757
Entrez Gene ID: (Human) 1497, (Mouse) 83429, (Rat) 287478
lens development in camera-type eye
glutathione metabolic process
transport
brain development
long-term memory
grooming behavior
adult walking behavior
visual learning
L-cystine transport
melanin biosynthetic process
ATP metabolic process
cognition
L-alpha-amino acid transmembrane transport
biological_process
cellular amino acid metabolic process
ion transport
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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