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Proteintech
CTSO Polyclonal Antibody
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Product Details
14296-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CTSO Fusion Protein Ag5651 (1-321 aa encoded by BC049206)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDVRALPWL PWLLWLLCRG GGDADSRAPF TPTWPRSRER EAAAFRESLN RHRYLNSLFP SENSTAFYGI NQFSYLFPEE FKAIYLRSKP SKFPRYSAEV HMSIPNVSLP LRFDWRDKQV VTQVRNQQMC GGCWAFSVVG AVESAYAIKG KPLEDLSVQQ VIDCSYNNYG CNGGSTLNAL NWLNKMQVKL VKDSEYPFKA QNGLCHYFSG SHSGFSIKGY SAYDFSDQED EMAKALLTFG PLVVIVDAVS WQDYLGGIIQ HHCSSGEANH AVLITGFDKT GSTPYWIVRN SWGSSWGVDG YAHVKMGSNV CGIADSVSSI FV (1-321 aa encoded by BC049206)
Target Information
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cathepsin O; similar to cathepsin O
Gene Aliases: A330105D01Rik; A430056C07; AI118514; CTSO; CTSO1
UniProt ID: (Human) P43234, (Mouse) Q8BM88
Entrez Gene ID: (Human) 1519, (Mouse) 229445, (Rat) 684529
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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