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Immunogen sequence: LSPDSFCLGF SEGAACGQSL EERSKTLAEV KPILQATGFP WHVVALEEVF SLPPSVLWCS AQELVGSEGA YKAAVDSFLQ QQH
Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 70%.
Cytoplasmic tRNA 2-thiolation protein 2 (CUT2), also named as C16orf84 or NCS2, is a 515 amino acid protein, which belongs to the CUT2 family. C16orf84 localizes in the cytoplasm and Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). C16orf84 may act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thio-carboxylated URM1 onto the uridine of tRNAs at wobble position.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytoplasmic tRNA 2-thiolation protein 2; Cytosolic thiouridylase subunit 2; cytosolic thiouridylase subunit 2 homolog
Gene Aliases: C16orf84; CTU2; NCS2; UPF0432
UniProt ID: (Human) Q2VPK5
Entrez Gene ID: (Human) 348180
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