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Proteintech
CUL7 Polyclonal Antibody
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Product Details
13738-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CUL7 Fusion Protein Ag4675 (1348-1698 aa encoded by BC033647)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GKEHKSEKE EEAGAAAVVD VAEGEEEEEE NEDLYYEGAM PEVSVLVLSR HSWPVASICH TLNPRTCLPS YLRGTLNRYS NFYNKSQSHP ALERGSQRRL QWTWLGWAEL QFGNQTLHVS TVQMWLLLYL NDLKAVSVES LLAFSGLSAD MLNQAIGPLT SSRGPLDLHE QKDIPGGVLK IRDGSKEPRS RWDIVRLIPP QTYLQAEGED GQNLEKRRNL LNCLIVRILK AHGDEGLHID QLVCLVLEAW QKGPCPPRGL VSSLGKGSAC SSTDVLSCIL HLLGKGTLRR HDDRPQVLSY AVPVTVMEPH TESLNPGSSG PNPPLTFHTL QIRSRGVPYA SCTATQSFST FR (1348-1698 aa encoded by B C033647)
Target Information
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CUL-7; Cullin-7
Gene Aliases: 3M1; CUL7; dJ20C7.5; KIAA0076
UniProt ID: (Human) Q14999
Entrez Gene ID: (Human) 9820
microtubule cytoskeleton organization
mitotic cytokinesis
vasculogenesis
epithelial to mesenchymal transition
placenta development
proteolysis
ubiquitin-dependent protein catabolic process
Golgi organization
regulation of mitotic nuclear division
viral process
protein ubiquitination
IRE1-mediated unfolded protein response
positive regulation of dendrite morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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