Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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In direct ELISAs, 100% cross-reactivity with recombinant mouse (rm) CXCL2 is observed and no cross-reactivity with recombinant human (rh) VIC, rmVIC, rhCCL3L1, rhCCL4L1, or recombinant canine IL-8 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; C-X-C motif chemokine 2; C-X-C motif chemokine 3; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); chemokine (C-X-C motif) ligand 2; chemokine (C-X-C motif) ligand 3; CXC; CXC motif chemokine; CXCL; fibroblast secretory protein; GRO a; gro beta; gro gamma; GRO α; GRO-alpha(1-73); Gro-beta; GRO-gamma; GRO-gamma(1-73); GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GRO2 oncogene; GRO3 oncogene; GROalpha; Growth-regulated alpha protein; Growth-regulated protein beta; Growth-regulated protein gamma; GROα; Macrophage inflammatory protein 2-alpha; Macrophage inflammatory protein 2-beta; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; melanoma growth stimulatory activity beta; melanoma growth stimulatory activity gamma; MGSA; MGSA alpha; MGSA beta; MGSA gamma; MIP2-alpha; MIP2-beta; NAP-3; NAP3; Neutrophil-activating protein 3
Gene Aliases: CINC-2a; CINC-2b; CXCL1; CXCL2; CXCL3; FSP; GRO; GRO1; GRO2; GRO3; GROA; GROB; GROG; MGSA; MGSA-a; MGSA-b; MIP-2a; MIP-2b; MIP2; MIP2A; MIP2B; NAP-3; SCYB1; SCYB2; SCYB3
UniProt ID: (Human) P09341, (Human) P19875, (Human) P19876
Entrez Gene ID: (Human) 2919, (Human) 2920, (Human) 2921
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