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          • Primary Antibodies ›
          • CXCL11 Antibodies
          The PeproTech website has now moved to Thermofisher.com. All orders for PeproTech products must be placed on thermofisher.com or offline via phone, fax, email, or distributor partner. For any questions, please contact PeproTech.CustomerService@thermofisher.com

          Invitrogen

          CXCL11 Polyclonal Antibody, PeproTech®

          3 References
          View all (18) CXCL11 antibodies

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          Datasheet
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          Datasheet
          Protocols
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          Cite CXCL11 Polyclonal Antibody, PeproTech®

          • Antibody Testing Data (3)
          CXCL11 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          CXCL11 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          CXCL11 Antibody (500-P132-1MG) in WB

          Western Blot: To detect Human I-TAC (CXCL11) by Western Blot analysis CXCL11 Polyclonal Antibody (Product # 500-P132-1MG) can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human I-TAC (CXCL11) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CXCL11 Antibody in Western Blot (WB)
          CXCL11 Antibody in Western Blot (WB)
          CXCL11 Antibody in ELISA (ELISA)

          Product Details

          500-P132-1MG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-0.2 µg/mL
          -

          ELISA (ELISA)

          0.5-2.0 µg/mL
          View 1 publication 1 publication

          Immunostaining (IS)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E.coli-derived Recombinant Human I-TAC (CXCL11)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.1-1.0 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          -20°C

          Shipping conditions

          Ambient

          RRID

          AB_2929396

          Product Specific Information

          AA Sequence of recombinant protein: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF.

          Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human I-TAC (CXCL11). Anti-Human I-TAC (CXCL11)-specific antibody was purified by affinity chromatography employing an immobilized Human I-TAC (CXCL11) matrix.

          Sandwich ELISA: To detect Human I-TAC (CXCL11) by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human I-TAC (CXCL11) (500-P132Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human I-TAC (CXCL11).

          Western Blot: To detect Human I-TAC (CXCL11) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human I-TAC (CXCL11) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

          Target Information

          Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Beta-R1; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 11; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; CXCL; H174; I-TAC; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; IP-9; MGC102770; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; Small-inducible cytokine B11

          View more View less

          Gene Aliases: b-R1; CXCL11; H174; I-TAC; IP-9; IP9; ITAC; SCYB11; SCYB9B

          View more View less

          UniProt ID: (Human) O14625

          View more View less

          Entrez Gene ID: (Human) 6373

          View more View less

          Function(s)
          protein binding chemokine activity heparin binding CXCR3 chemokine receptor binding
          Process(es)
          positive regulation of leukocyte chemotaxis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway cell-cell signaling T cell chemotaxis positive regulation of cAMP metabolic process response to lipopolysaccharide regulation of cell proliferation positive regulation of cAMP-mediated signaling positive regulation of release of sequestered calcium ion into cytosol chemokine-mediated signaling pathway
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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