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Product Details
16702-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYP20A1 Fusion Protein Ag10099 (112-462 aa encoded by BC020616)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SGGGSVSEN HMREKLYENG VTDSLKSNFA LLLKLSEELL DKWLSYPETQ HVPLSQHMLG FAMKSVTQMV MGSTFEDDQE VIRFQKNHGT VWSEIGKGFL DGSLDKNMTR KKQYEDALMQ LESVLRNIIK ERKGRNFSQH IFIDSLVQGN LNDQQILEDS MIFSLASCII TAKLCTWAIC FLTTSEEVQK KLYEEINQVF GNGPVTPEKI EQLRYCQHVL CETVRTAKLT PVSAQFQDIE GKIDRFIIPR ETLVLYALGV VLQDPNTWPS PHKFDPDRFD DELVMKTFSS LGFSGTQECP ELRFAYMVTT VLLSVLVKRL HLLSVEGQVI ETKYELVTSS REEAWITVSK RY (112-462 aa encoded by BC020616)
Target Information
CYP20A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D, E)T, suggesting that its substrate may carry its own oxygen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytochrome P450 20A1; cytochrome P450 monooxygenase; cytochrome P450, 20a1; cytochrome P450, family 20, subfamily A, polypeptide 1
Gene Aliases: A930011N14Rik; CYP-M; CYP20A1; Cypm; UNQ667/PRO1301
UniProt ID: (Human) Q6UW02, (Mouse) Q8BKE6, (Rat) Q6P7D4
Entrez Gene ID: (Human) 57404, (Mouse) 77951, (Rat) 316435
monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
heme binding
oxidoreductase activity
fluorene oxygenase activity
mono-butyltin dioxygenase activity
tri-n-butyltin dioxygenase activity
di-n-butyltin dioxygenase activity
methylsilanetriol hydroxylase activity
methyl tertiary butyl ether 3-monooxygenase activity
4-nitrocatechol 4-monooxygenase activity
4-chlorophenoxyacetate monooxygenase activity
tert-butanol 2-monooxygenase activity
alpha-pinene monooxygenase activity
dimethylsilanediol hydroxylase activity
ammonia monooxygenase activity
hydroxymethylsilanetriol oxidase activity
2-hydroxyisobutyrate 3-monooxygenase activity
alpha-pinene dehydrogenase activity
bisphenol A hydroxylase B activity
2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
9-fluorenone-3,4-dioxygenase activity
anthracene 9,10-dioxygenase activity
2-(methylthio)benzothiazole monooxygenase activity
2-hydroxybenzothiazole monooxygenase activity
benzothiazole monooxygenase activity
2,6-dihydroxybenzothiazole monooxygenase activity
pinacolone 5-monooxygenase activity
thioacetamide S-oxygenase activity
thioacetamide S-oxide S-oxygenase activity
endosulfan monooxygenase I activity
N-nitrodimethylamine hydroxylase activity
4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity
endosulfan ether monooxygenase activity
pyrene 4,5-monooxygenase activity
pyrene 1,2-monooxygenase activity
1-hydroxypyrene 6,7-monooxygenase activity
1-hydroxypyrene 7,8-monooxygenase activity
phenylboronic acid monooxygenase activity
spheroidene monooxygenase activity
metal ion binding
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