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Invitrogen
CYP4A11/CYP4A22 Polyclonal Antibody
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FIGURE: 1 / 2
CYP4A11/CYP4A22 Antibody (PA5-102018) in ICC/IF
Immunofluorescent analysis of CYP4A11/CYP4A22 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CYP4A11/CYP4A22 polyclonal antibody (Product # PA5-102018) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Ale... View More
Product Details
PA5-102018
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CYP4A11(Accession Q02928), corresponding to amino acid residues F150-C200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815894
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 4A11/22.
Target Information
Cytochrome P450 4A22 (CYP4A22) is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; CYP4AII; CYPIVA11; CYPIVA22; Cytochrome P-450HK-omega; Cytochrome P450 4A11; Cytochrome P450 4A22; cytochrome P450 4A22K; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, family 4, subfamily A, polypeptide 22; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; P450HL-omega
Gene Aliases: CP4Y; CYP4A11; CYP4A2; CYP4A22; CYP4AII
UniProt ID: (Human) Q02928, (Human) Q5TCH4
Entrez Gene ID: (Human) 1579, (Human) 284541
long-chain fatty acid metabolic process
renal water homeostasis
pressure natriuresis
fatty acid metabolic process
leukotriene metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
positive regulation of icosanoid secretion
leukotriene B4 catabolic process
sodium ion homeostasis
oxidation-reduction process
omega-hydroxylase P450 pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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