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CYP4Z1/CYP4Z2P Antibody (PA5-67705) in IHC (P)
Immunohistochemical analysis of CYP4Z1/CYP4Z2P in paraffin-embedded human tonsil. 1) CYP4Z1/CYP4Z2P Polyclonal Antibody (Product # PA5-67705) was diluted at 1:200(4° overnight). 2) Tris-EDTA,pH9.0 was used for antigen retrieval. 3) Secondary antibody was diluted at 1:200 (room temperature, 30 min).
Product Details
PA5-67705
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human CYP4Z1/CYP4Z2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691468
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CYP4Z1/2; CYPIVZ1; Cytochrome P450 4Z1; cytochrome P450, family 4, subfamily Z, polypeptide 1; Laurate 7-monooxygenase; P450 4Z1/2
Gene Aliases: CYP4A20; CYP4Z1; UNQ3060/PRO9882
UniProt ID: (Human) Q86W10
Entrez Gene ID: (Human) 199974, (Human) 163720
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