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Proteintech
CYSLTR1 Polyclonal Antibody
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Product Details
27372-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYSLTR1 Fusion Protein Ag24961 (252-337 aa encoded by BC035750)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QRTIHLHFL HNETKPCDSV LTMQKSVVIT LSLAASNCCF DPLLYFFSGG NFRKRLSTFR KHSLSSVTYV PRKKASLPEK GEEICKV (252-337 aa encoded by BC035750 )
Target Information
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cys-LT1 receptor; CysLT 1; CysLT(1); CysLT1 receptor; CysLTR1; cysteinyl leukotriene 1 receptor short isoform; Cysteinyl leukotriene D4 receptor; Cysteinyl leukotriene receptor 1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 receptor; LTD4R; MGC46139
Gene Aliases: BB147369; CYSLT1; CYSLT1R; CYSLTR; CYSLTR1; HMTMF81
UniProt ID: (Human) Q9Y271, (Mouse) Q99JA4, (Rat) Q924T8
Entrez Gene ID: (Human) 10800, (Mouse) 58861, (Rat) 114099
calcium ion transport
chemotaxis
inflammatory response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of angiogenesis
positive regulation of vasoconstriction
circulatory system process
defense response
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
respiratory gaseous exchange
leukotriene signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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