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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CYSLTR2 Antibodies

          Invitrogen

          CYSLTR2 Polyclonal Antibody

          View all (6) CYSLTR2 antibodies
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          Cite CYSLTR2 Polyclonal Antibody

          • Antibody Testing Data (1)
          CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 1

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          CYSLTR2 Antibody (PA5-32716) in IHC (P)

          Immunohistochemistry analysis of CYSLTR2 in human heart. Samples were incubated with CYSLTR2 polyclonal antibody (Product # PA5-32716). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          PA5-32716

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          10 µg/mL
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human CYSLTR2 / CYSLT2.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.1% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2550179

          Product Specific Information

          Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Marmoset (80%).

          For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

          Target Information

          Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CysLT(2); CysLT-2; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; hGPCR21; HPN321

          View more View less

          Gene Aliases: CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146

          View more View less

          UniProt ID: (Human) Q9NS75

          View more View less

          Entrez Gene ID: (Human) 57105

          View more View less

          Function(s)
          cysteinyl leukotriene receptor activity leukotriene receptor activity protein binding G-protein coupled peptide receptor activity
          Process(es)
          immune response phospholipase C-activating G-protein coupled receptor signaling pathway neuropeptide signaling pathway positive regulation of cell death positive regulation of angiogenesis leukotriene signaling pathway positive regulation of ERK1 and ERK2 cascade
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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