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Invitrogen
CaMKK alpha Polyclonal Antibody
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Product Details
PA5-78908
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK (10-31aa QDPRAELVDRVAAINVAHLEEA).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746024
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Rat Brain Tissue, Mouse Brain Tissue, Mouse Brain Tissue, rat brain tissue, mouse brain tissue, human U-87MG whole cell. IHC: Rat Brain Tissue.
Target Information
CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha CaMKK; calcium calmodulin dependent protein kinase kinase alpha; Calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; Calcium/calmodulin-dependent protein kinase kinase alpha; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; CaM-KK 1; CaM-KK alpha; caMKK 1; caMKK alpha; CAMKK alpha protein
Gene Aliases: AI846603; Camkk; CAMKK1; CAMKKA; CaMKKalpha
UniProt ID: (Human) Q8N5S9, (Mouse) Q8VBY2, (Rat) P97756
Entrez Gene ID: (Human) 84254, (Mouse) 55984, (Rat) 60341
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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