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Invitrogen
Calbindin D28K Monoclonal Antibody (4H7)
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Calbindin D28K Antibody (MA5-47438) in IHC (PFA)
Immunohistochemistry analysis of Calbindin D28K in rat brain cerebellum section. Samples were stained with Calbindin D28K monoclonal antibody (Product # MA5-47438) using a dilution of 1:1,000 (green). Costained with rabbit pAb to calretinin dilution 1:5,000 in red. The blue is DAPI staining of nuclear DNA Following transcardial perfusion with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45... View More
Product Details
MA5-47438
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4H7
Immunogen
Full-length recombinant human calbindin protein expressed in and purified from E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2942420
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; Calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; Spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: BOS_14108; Brain-2; CAB27; CaBP28K; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Bovine) P04467, (Human) P05937, (Rat) P07171, (Mouse) P12658
Entrez Gene ID: (Bovine) 539930, (Pig) 100153645, (Human) 793, (Rat) 83839, (Mouse) 12307
learning or memory
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
vitamin D metabolic process
regulation of synaptic plasticity
regulation of cytosolic calcium ion concentration
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
calcium ion homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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