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Proteintech
Calcipressin 1 Polyclonal Antibody
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Product Details
14869-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Calcipressin 1 Fusion Protein Ag6457 (1-197 aa encoded by BC002864)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEEVDLQDL PSATIACHLD PRVFVDGLCR AKFESLFRTY DKDITFQYFK SFKRVRINFS NPFSAADARL QLHKTEFLGK EMKLYFAQTL HIGSSHLAPP NPDKQFLISP PASPPVGWKQ VEDATPVINY DLLYAISKLG PGEKYELHAA TDTTPSVVVH VCESDQEKEE EEEMERMRRP KPKIIQTRRP EYTPIHLS (1-197 aa encoded by BC002864)
Target Information
The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adapt78; calcineurin inhibitor; Calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; Down syndrome critical region protein 1 homolog; MCIP1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Regulator of calcineurin 1
Gene Aliases: ADAPT78; CALP1L; CSP1; DSC1; DSCR1; MCIP1; RCAN1; RCN1
UniProt ID: (Human) P53805, (Mouse) Q9JHG6
Entrez Gene ID: (Human) 1827, (Mouse) 54720
response to ischemia
response to stress
response to oxidative stress
short-term memory
calcium-mediated signaling
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
regulation of phosphoprotein phosphatase activity
skeletal muscle fiber development
regulation of catalytic activity
regulation of calcineurin-NFAT signaling cascade
regulation of transcription, DNA-templated
signal transduction
central nervous system development
blood circulation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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