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Product Details
OSC00074W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from human Calcipressin 1 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: RCAN1.
Target Information
The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adapt78; calcineurin inhibitor; Calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region homolog 1; Down syndrome critical region protein 1; Down syndrome critical region protein 1 homolog; MCIP1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Regulator of calcineurin 1
Gene Aliases: ADAPT78; CALP1L; CSP1; DSC1; DSCR1; MCIP1; RCAN1; RCN1
UniProt ID: (Human) P53805, (Mouse) Q9JHG6, (Rat) Q6IN33
Entrez Gene ID: (Human) 1827, (Mouse) 54720, (Rat) 266766
response to ischemia
response to stress
response to oxidative stress
short-term memory
calcium-mediated signaling
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
regulation of phosphoprotein phosphatase activity
skeletal muscle fiber development
regulation of catalytic activity
regulation of calcineurin-NFAT signaling cascade
regulation of transcription, DNA-templated
signal transduction
central nervous system development
blood circulation
skeletal muscle tissue development
response to mechanical stimulus
response to estrogen
negative regulation of smooth muscle cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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