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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Calcium Sensing Receptor Antibodies

          Invitrogen

          Calcium Sensing Receptor Monoclonal Antibody (5C10, ADD)

          Advanced Verification
          53 Published Figures
          69 References
          View all (23) Calcium Sensing Receptor antibodies

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          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite Calcium Sensing Receptor Monoclonal Antibody (5C10, ADD)

          • Antibody Testing Data (5)
          • Published Figures (53)
          • Advanced Verification (1)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Calcium Sensing Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 59

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          Calcium Sensing Receptor Antibody (MA1-934) in IHC (P)

          Immunohistochemistry was performed on normal biopsies of deparaffinized Human kidney tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:100 with a mouse monoclonal ant... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Calcium Sensing Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Calcium Sensing Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Calcium Sensing Receptor Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Immunocytochemistry (ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Calcium Sensing Receptor Antibody in Western Blot, Immunohistochemistry (Paraffin) (WB, IHC (P))
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Immunohistochemistry (IHC)
          Calcium Sensing Receptor Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot, Immunoprecipitation (WB, IP)
          Calcium Sensing Receptor Antibody in Western Blot (WB)
          Calcium Sensing Receptor Antibody in Western Blot, Immunoprecipitation (WB, IP)
          Calcium Sensing Receptor Antibody in Flow Cytometry (Flow)
          Calcium Sensing Receptor Antibody in Flow Cytometry (Flow)
          Calcium Sensing Receptor Antibody

          Product Details

          MA1-934

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          2 µg/mL
          View 32 publications 32 publications

          Immunohistochemistry (IHC)

          -
          View 17 publications 17 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100
          View 5 publications 5 publications

          Immunohistochemistry (Frozen) (IHC (F))

          2 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          -
          View 12 publications 12 publications

          Flow Cytometry (Flow)

          -
          View 2 publications 2 publications

          ELISA (ELISA)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Bovine, Human, Mouse, Rat

          Published species

          Human, Mouse, Pig, Rat

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          5C10, ADD

          Immunogen

          Synthetic peptide corresponding to residues (214) A D D D Y G R P G I E K F RE E A E E R D I (235) of human calcium sensing receptor.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS with 1mg/mL BSA

          Contains

          0.05% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_325374

          Product Specific Information

          MA1-934 detects human, bovine, mouse, and rat calcium sensing receptor.

          MA1-934 has been successfully used in Western blot, immunohistochemistry, and ELISA procedures. By Western blot, this antibody detects an ~ 150 and 130 kDa proteins from human HEK-293 cells.This antibody has also been used in immunohistochemical on frozen bovine parathyroid gland and rat thyroid gland.

          The MA1-934 immunogen is a synthetic peptide corresponding to residues (214) A D D D Y G R P G I E K F RE E A E E R D I (235) of human calcium sensing receptor.

          Target Information

          Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: BoPCaR1; Ca sensing receptor; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1

          View more View less

          Gene Aliases: BOS_823; CAR; CASR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1

          View more View less

          UniProt ID: (Bovine) P35384, (Human) P41180, (Rat) P48442, (Mouse) Q9QY96

          View more View less

          Entrez Gene ID: (Bovine) 281038, (Human) 846, (Rat) 24247, (Mouse) 12374

          View more View less

          Function(s)
          G-protein coupled receptor activity phosphatidylinositol phospholipase C activity protein binding magnesium ion binding integrin binding calcium ion binding drug binding polyamine binding protein kinase binding ion channel binding signal transducer activity
          Process(es)
          ossification calcium ion transport cellular calcium ion homeostasis JNK cascade positive regulation of cell proliferation vasodilation detection of calcium ion G-protein coupled receptor signaling pathway chemosensory behavior anatomical structure morphogenesis calcium ion import response to ischemia apoptotic process adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway response to metal ion positive regulation of gene expression response to organic cyclic compound positive regulation of insulin secretion positive regulation of ATPase activity cellular response to hepatocyte growth factor stimulus positive regulation of vasoconstriction branching morphogenesis of an epithelial tube positive regulation of positive chemotaxis response to calcium ion regulation of calcium ion transport fat pad development cellular response to vitamin D cellular response to glucose stimulus cellular response to low-density lipoprotein particle stimulus cellular response to hypoxia response to fibroblast growth factor positive regulation of calcium ion import cellular response to peptide signal transduction
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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