Proteintech

Calnexin Polyclonal Antibody

Calnexin Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 17

Calnexin Antibody (10427-2-AP) in ICC/IF

Immunofluorescent analysis of (10% Formaldehyde) fixed HepG2 cells using Calnexin antibody (Product # 10427-2-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). The cytoskeleton was stained with CL594-Phalloidin (red).

Calnexin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Calnexin Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

10427-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:20,000

View 223 publications 223 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 41 publications 41 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

ELISA (ELISA)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Hamster, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Calnexin Fusion Protein Ag0697 (1-273 aa encoded by BC003552)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.39 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEGKWLLCM LLVLGTAIVE AHDGHDDDVI DIEDDLDDVI EEVEDSKPDT TAPPSSPKVT YKAPVPTGEV YFADSFDRGT LSGWILSKAK KDDTDDEIAK YDGKWEVEEM KESKLPGDKG LVLMSRAKHH AISAKLNKPF LFDTKPLIVQ YEVNFQNGIE CGGAYVKLLS KTPELNLDQF HDKTPYTIMF GPDKCGEDYK LHFIFRHKNP KTGIYEEKHA KRPDADLKTY FTDKKTHLYT LILNPDNSFE ILVDQSVVNS GNLLNDMTPP VNPS (1-273 aa encoded by BC003552)

Target Information

Calnexin, also referred to as IP90, p88 and p90, is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP78 and GRP94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Clinical and translational medicine

Zhang Y,Yu X,Sun R,Min J,Tang X,Lin Z,Xie S,Li X,Lu S,Tian Z,Gu C,Teng L,Yang Y

Tue Feb 01 00:00:00 UTC 2022

Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.

Biomedicines

Jiang Y,Chai X,Chen S,Chen Z,Tian H,Liu M,Wu X

Fri Dec 02 00:00:00 UTC 2022

Plasma Extracellular Vesicle Long RNA in Diagnosis and Prediction in Small Cell Lung Cancer.

Cancers

Liu C,Chen J,Liao J,Li Y,Yu H,Zhao X,Sun S,Hu Z,Zhang Y,Zhu Z,Fan M,Huang S,Wang J

Wed Nov 09 00:00:00 UTC 2022

The endoplasmic reticulum adopts two distinct tubule forms.

Proceedings of the National Academy of Sciences of the United States of America

Wang B,Zhao Z,Xiong M,Yan R,Xu K

Tue May 03 00:00:00 UTC 2022

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.

Journal of medicinal chemistry

Bian M,Fan R,Yang Z,Chen Y,Xu Z,Lu Y,Liu W

Thu Feb 10 00:00:00 UTC 2022

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.

Journal of medicinal chemistry

Bian M,Fan R,Yang Z,Chen Y,Xu Z,Lu Y,Liu W

Thu Feb 10 00:00:00 UTC 2022

miR-29a-3p in Exosomes from Heme Oxygenase-1 Modified Bone Marrow Mesenchymal Stem Cells Alleviates Steatotic Liver Ischemia-Reperfusion Injury in Rats by Suppressing Ferroptosis via Iron Responsive Element Binding Protein 2.

Oxidative medicine and cellular longevity

Li X,Wu L,Tian X,Zheng W,Yuan M,Tian X,Zuo H,Song H,Shen Z

Tue Jun 21 00:00:00 UTC 2022

Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.

Frontiers in cardiovascular medicine

Wang S,Shi M,Zhou J,Wang W,Zhang Y,Li Y

Tue May 10 00:00:00 UTC 2022

Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.

Signal transduction and targeted therapy

Li GN,Zhao XJ,Wang Z,Luo MS,Shi SN,Yan DM,Li HY,Liu JH,Yang Y,Tan JH,Zhang ZY,Chen RQ,Lai HL,Huang XY,Zhou JF,Ma D,Fang Y,Gao QL

Mon Sep 12 00:00:00 UTC 2022

SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.

Signal transduction and targeted therapy

Zheng Y,Deng J,Han L,Zhuang MW,Xu Y,Zhang J,Nan ML,Xiao Y,Zhan P,Liu X,Gao C,Wang PH

Mon Jan 24 00:00:00 UTC 2022

Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.

Cell death & disease

Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G

Thu Oct 06 00:00:00 UTC 2022

Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.

Breast cancer research and treatment

Li C,Li R,Hu X,Zhou G,Jiang G

Fri Apr 01 00:00:00 UTC 2022

TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia.

Brain : a journal of neurology

Tábara LC,Al-Salmi F,Maroofian R,Al-Futaisi AM,Al-Murshedi F,Kennedy J,Day JO,Courtin T,Al-Khayat A,Galedari H,Mazaheri N,Protasoni M,Johnson M,Leslie JS,Salter CG,Rawlins LE,Fasham J,Al-Maawali A,Voutsina N,Charles P,Harrold L,Keren B,Kunji ERS,Vona B,Jelodar G,Sedaghat A,Shariati G,Houlden H,Crosby AH,Prudent J,Baple EL

Wed Sep 14 00:00:00 UTC 2022

Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.

eLife

Fu J,Zhou M,Gritsenko MA,Nakayasu ES,Song L,Luo ZQ

Thu Jan 27 00:00:00 UTC 2022

Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.

Frontiers in oncology

Liang S,Zhu C,Suo C,Wei H,Yu Y,Gu X,Chen L,Yuan M,Shen S,Li S,Sun L,Gao P

Fri Sep 27 00:00:00 UTC 2024

ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

Nature cancer

Zhang T,Sun L,Hao Y,Suo C,Shen S,Wei H,Ma W,Zhang P,Wang T,Gu X,Li ST,Chen Z,Yan R,Zhang Y,Cai Y,Zhou R,Jia W,Huang F,Gao P,Zhang H

Sat Jan 01 00:00:00 UTC 2022

Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.

Redox biology

Ge X,He Z,Cao C,Xue T,Jing J,Ma R,Zhao W,Liu L,Jueraitetibaike K,Ma J,Feng Y,Qian Z,Zou Z,Chen L,Fu C,Song N,Yao B

Mon Aug 01 00:00:00 UTC 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 UTC 2022

Characterization and subcellular localization of Alongshan virus proteins.

Frontiers in microbiology

Zhao Y,Wu P,Liu L,Ma B,Pan M,Huang Y,Du N,Yu H,Sui L,Wang ZD,Hou Z,Liu Q

Sat Oct 15 00:00:00 UTC 2022

Hypoxic Cell-Derived Extracellular Vesicles Aggravate Rectal Injury Following Radiotherapy via MiR-122-5p.

Frontiers in cell and developmental biology

Xu Y,Ge Y,Chen X,Zhang Y,Chen H,Liu D,Lu Y,Liu Y,Tu W

Sat Jul 16 00:00:00 UTC 2022

UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.

Cell communication and signaling : CCS

Cen X,Chen Q,Wang B,Xu H,Wang X,Ling Y,Zhang X,Qin D

Mon Nov 28 00:00:00 UTC 2022

Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation.

International journal of pharmaceutics

Chen P,Tang S,Gao H,Zhang H,Chen C,Fang Z,Peng G,Weng H,Chen A,Zhang C,Qiu Z,Li S,Chen J,Chen L,Chen X

Mon Jul 25 00:00:00 UTC 2022

Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance.

Cell death & disease

Guo WH,Guo Q,Liu YL,Yan DD,Jin L,Zhang R,Yan J,Luo XH,Yang M

Thu Oct 27 00:00:00 UTC 2022

FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia.

Cell reports

Mei F,Hu J,Wu Z,Zhang G,Liu A,Li X,Zhu M,Gan Y,Liang L,Zhao X,Yuan Y,Meng X,Li Y,Jin Y,Jia J,Yin Y

Tue Jul 19 00:00:00 UTC 2022

Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE.

Redox biology

Li W,Luo LX,Zhou QQ,Gong HB,Fu YY,Yan CY,Li E,Sun J,Luo Z,Ding ZJ,Zhang QY,Mu HL,Cao YF,Ouyang SH,Kurihara H,Li YF,Sun WY,Li M,He RR

Thu Sep 01 00:00:00 UTC 2022

The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.

BMC biology

Nozawa K,Fujihara Y,Devlin DJ,Deras RE,Kent K,Larina IV,Umezu K,Yu Z,Sutton CM,Ye Q,Dean LK,Emori C,Ikawa M,Garcia TX,Matzuk MM

Wed Jul 13 00:00:00 UTC 2022

Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency.

Autophagy

Wang F,Yang Y,Boudagh G,Eskelinen EL,Klionsky DJ,Malek SN

Mon Aug 01 00:00:00 UTC 2022

Extracellular vesicle-derived long non-coding RNA as circulating biomarkers for endometriosis.

Reproductive biomedicine online

Shan S,Yang Y,Jiang J,Yang B,Yang Y,Sun F,Zhang J,Lin Y,Xu H

Sun May 01 00:00:00 UTC 2022

Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.

Respiratory research

Khodayari N,Oshins R,Mehrad B,Lascano JE,Qiang X,West JR,Holliday LS,Lee J,Wiesemann G,Eydgahi S,Brantly M

Tue Sep 06 00:00:00 UTC 2022

N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion.

Cellular and molecular life sciences : CMLS

Hobohm L,Koudelka T,Bahr FH,Truberg J,Kapell S,Schacht SS,Meisinger D,Mengel M,Jochimsen A,Hofmann A,Heintz L,Tholey A,Voss M

Sun Mar 13 00:00:00 UTC 2022

VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.

iScience

Dong X,Jiang D,Wang L,Zhao J,Yu L,Huang Y,Wu X,Zhu Y,Zhao Y,Zhao Q,Zhang G,Li X

Fri Apr 15 00:00:00 UTC 2022

Differential proteomic analysis of plasma-derived exosomes as diagnostic biomarkers for chronic HBV-related liver disease.

Scientific reports

Ye B,Shen Y,Chen H,Lin S,Mao W,Dong Y,Li X

Wed Aug 24 00:00:00 UTC 2022

miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia-reperfusion injury in steatotic grafts.

Journal of nanobiotechnology

Wu L,Tian X,Zuo H,Zheng W,Li X,Yuan M,Tian X,Song H

Fri Apr 22 00:00:00 UTC 2022

Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.

Bioengineered

Liu W,Feng Y,Wang X,Ding J,Li H,Guan H,Chen Z

Fri Apr 01 00:00:00 UTC 2022

SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.

Autophagy

Zhang X,Yang Z,Pan T,Long X,Sun Q,Wang PH,Li X,Kuang E

Tue Nov 01 00:00:00 UTC 2022

Aberrant Cholesterol Metabolism and Wnt/β-Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zheng S,Lin J,Pang Z,Zhang H,Wang Y,Ma L,Zhang H,Zhang X,Chen M,Zhang X,Zhao C,Qi J,Cao L,Wang M,He X,Sheng R

Sat Oct 01 00:00:00 UTC 2022

Proteomic and miRNA Profiles of Exosomes Derived from Myometrial Tissue in Laboring Women.

International journal of molecular sciences

Deng W,Wang X,Chen L,Wen B,Chen Y,Ji K,Liu H

Sat Oct 15 00:00:00 UTC 2022

Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.

Cell death discovery

Zhao Q,Chen H,Li X,Zeng B,Sun Z,Liu D,Chen Y,Zhang Y,Rosie Xing H,Wang J

Sat Apr 09 00:00:00 UTC 2022

Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.

Endocrine

Chen W,Li G,Li Z,Zhu J,Wei T,Lei J

Tue Mar 01 00:00:00 UTC 2022

A cryostat-based frozen section method to increase the yield of extracellular vesicles extracted from different tissues.

BioTechniques

Yang S,Qin W,Li X,Guo Q,Wang Y,Chen J,Li H,Zhang S,Min L

Mon Aug 01 00:00:00 UTC 2022

Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.

Current protocols

Bryant JD,Lei Y,VanPortfliet JJ,Winters AD,West AP

Tue Feb 01 00:00:00 UTC 2022

The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.

Frontiers in immunology

Li X,Wang W,Chen J,Xie B,Luo S,Chen D,Cai C,Li C,Li W

Tue Aug 30 00:00:00 UTC 2022

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

Life science alliance

Strohm L,Hu Z,Suk Y,Rühmkorf A,Sternburg E,Gattringer V,Riemenschneider H,Berutti R,Graf E,Weishaupt JH,Brill MS,Harbauer AB,Dormann D,Dengjel J,Edbauer D,Behrends C

Tue Nov 01 00:00:00 UTC 2022

Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy.

Endocrinology

Ma Q,Beal JR,Song X,Bhurke A,Bagchi IC,Bagchi MK

Sun Oct 23 00:00:00 UTC 2022

Preparation of Recombinant Human Collagen III Protein Hydrogels with Sustained Release of Extracellular Vesicles for Skin Wound Healing.

International journal of molecular sciences

Xu L,Liu Y,Tang L,Xiao H,Yang Z,Wang S

Fri Jun 03 00:00:00 UTC 2022

Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.

Frontiers in pharmacology

Kutchy NA,Ma R,Liu Y,Buch S,Hu G

Sat Jul 16 00:00:00 UTC 2022

Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma.

Journal of personalized medicine

Li G,Chen W,Gong Y,Wei T,Gong R,Zhu J,Li Z,Lei J

Wed Dec 07 00:00:00 UTC 2022

TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.

Molecular cell

Wang L,Li J,Wang Q,Ge MX,Ji J,Liu D,Wang Z,Cao Y,Zhang Y,Zhang ZR

Thu Sep 15 00:00:00 UTC 2022

Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.

Andrology

Zhuang J,Gao P,Chen H,Fang Z,Zheng J,Zhu D,Hou J

Tue Nov 01 00:00:00 UTC 2022

De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.

Cell reports

Spears ME,Lee N,Hwang S,Park SJ,Carlisle AE,Li R,Doshi MB,Armando AM,Gao J,Simin K,Zhu LJ,Greer PL,Quehenberger O,Torres EM,Kim D

Tue Sep 27 00:00:00 UTC 2022

De novo sphingolipid biosynthesis necessitates detoxification in cancer cells.

Cell reports

Spears ME,Lee N,Hwang S,Park SJ,Carlisle AE,Li R,Doshi MB,Armando AM,Gao J,Simin K,Zhu LJ,Greer PL,Quehenberger O,Torres EM,Kim D

Tue Sep 27 00:00:00 UTC 2022

The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.

Journal of virology

Shi J,Li Z,Xu R,Zhang J,Zhou Q,Gao R,Lu H,Lan Y,Zhao K,He H,Gao F,He W

Wed Jan 12 00:00:00 UTC 2022

The activity of disease-causative STING variants can be suppressed by wild-type STING through heterocomplex formation.

Frontiers in cell and developmental biology

Shindo R,Kuchitsu Y,Mukai K,Taguchi T

Tue Nov 29 00:00:00 UTC 2022

SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.

Journal of medical virology

Han L,Zheng Y,Deng J,Nan ML,Xiao Y,Zhuang MW,Zhang J,Wang W,Gao C,Wang PH

Tue Nov 01 00:00:00 UTC 2022

Extracellular vesicles derived from endometrial epithelial cells deliver exogenous miR-92b-3p to affect the function of embryonic trophoblast cells via targeting TSC1 and DKK3.

Reproductive biology and endocrinology : RB&E

Hua R,Liu Q,Lian W,Kang TT,Gao D,Huang C,Wang Y,Lei M

Tue Oct 25 00:00:00 UTC 2022

Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis.

Brain sciences

Wang Y,Xu X,Chen H,Zhu M,Guo X,Gao F

Sun Jun 26 00:00:00 UTC 2022

Atrophic skeletal muscle fibre-derived small extracellular vesicle miR-690 inhibits satellite cell differentiation during ageing.

Journal of cachexia, sarcopenia and muscle

Shao X,Gong W,Wang Q,Wang P,Shi T,Mahmut A,Qin J,Yao Y,Yan W,Chen D,Chen X,Jiang Q,Guo B

Thu Dec 01 00:00:00 UTC 2022

The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE^-/- mice.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Shen Y,Gu HM,Zhai L,Wang B,Qin S,Zhang DW

Sat Oct 01 00:00:00 UTC 2022

Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.

Stem cell research & therapy

Zhou H,Shen X,Yan C,Xiong W,Ma Z,Tan Z,Wang J,Li Y,Liu J,Duan A,Liu F

Sat Jul 16 00:00:00 UTC 2022

TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication.

Journal of virology

Yan F,Yang W,Wang X,Gao G

Wed Sep 14 00:00:00 UTC 2022

The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.

Signal transduction and targeted therapy

Zhang J,Huang F,Xia B,Yuan Y,Yu F,Wang G,Chen Q,Wang Q,Li Y,Li R,Song Z,Pan T,Chen J,Lu G,Zhang H

Wed May 12 00:00:00 UTC 2021

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.

Proceedings of the National Academy of Sciences of the United States of America

Zhang Y,Chen Y,Li Y,Huang F,Luo B,Yuan Y,Xia B,Ma X,Yang T,Yu F,Liu J,Liu B,Song Z,Chen J,Yan S,Wu L,Pan T,Zhang X,Li R,Huang W,He X,Xiao F,Zhang J,Zhang H

Tue Jun 08 00:00:00 UTC 2021

Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.

Journal of immunology (Baltimore, Md. : 1950)

Torres-Odio S,Lei Y,Gispert S,Maletzko A,Key J,Menissy SS,Wittig I,Auburger G,West AP

Thu Apr 15 00:00:00 UTC 2021

Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.

Animals : an open access journal from MDPI

Ding Q,Jin M,Kalds P,Meng C,Wang H,Zhong J,Wang X,Chen Y

Mon Nov 08 00:00:00 UTC 2021

Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.

Oncology letters

Cao B,Wang P,Gu L,Liu J

Thu Apr 01 00:00:00 UTC 2021

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.

Nature cell biology

Shi M,Huang XY,Ren XY,Wei XY,Ma Y,Lin ZZ,Liu DT,Song L,Zhao TJ,Li G,Yao L,Zhu M,Zhang C,Xie C,Wu Y,Wu HM,Fan LP,Ou J,Zhan YH,Lin SY,Lin SC

Mon Mar 01 00:00:00 UTC 2021

SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.

Toxicology and applied pharmacology

Huang R,Hao C,Wang D,Zhao Q,Li C,Wang C,Yao W

Thu Jul 01 00:00:00 UTC 2021

Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.

Frontiers in cell and developmental biology

Li S,Liao Z,Luo R,Song Y,Wang K,Feng X,Ou Y,Wu X,Zhang Y,Gao Y,Yin H,Yang C

Sat Jul 10 00:00:00 UTC 2021

SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.

Acta pharmaceutica Sinica. B

Long F,Yang D,Wang J,Wang Q,Ni T,Wei G,Zhu Y,Liu X

Sat May 01 00:00:00 UTC 2021

Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.

Aging

Wang Y,Xu Z,Wang X,Zheng J,Peng L,Zhou Y,Song Y,Lu Z

Mon Apr 19 00:00:00 UTC 2021

Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.

Bioactive materials

Huang J,Yu M,Yin W,Liang B,Li A,Li J,Li X,Zhao S,Liu F

Wed Sep 01 00:00:00 UTC 2021

Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.

Veterinary microbiology

Xu Q,Huang L,Xing J,Zhang J,Li H,Liu L,Hu C,Liao M,Yue J,Qi W

Thu Apr 01 00:00:00 UTC 2021

Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.

Small (Weinheim an der Bergstrasse, Germany)

Zhang J,Fu B,Li M,Mi S

Fri Jan 01 00:00:00 UTC 2021

LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.

Frontiers in oncology

Xiong J,Wu L,Huang L,Wu C,Liu Z,Deng W,Ma S,Zhou Z,Yu H,Cao K

Sat Nov 13 00:00:00 UTC 2021

hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.

International journal of molecular sciences

Li C,Qin F,Wang W,Ni Y,Gao M,Guo M,Sun G

Sun Nov 28 00:00:00 UTC 2021

FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.

The Journal of cell biology

Chen F,Yan B,Ren J,Lyu R,Wu Y,Guo Y,Li D,Zhang H,Hu J

Mon May 03 00:00:00 UTC 2021

VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.

Molecular biology of the cell

Du Y,Wang J,Xiong J,Fang N,Ji WK

Sun Aug 01 00:00:00 UTC 2021

Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabolism in mice or hamster.

Biochimica et biophysica acta. Molecular and cell biology of lipids

He B,Kang S,Chen Z,Liu X,Wang J,Li X,Liu X,Zheng L,Luo M,Wang Y

Mon Nov 01 00:00:00 UTC 2021

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.

Cell calcium

Chen Y,Hu M,Deng F,Wang P,Lin J,Zheng Z,Liu Y,Dong L,Lu X,Chen Z,Zhou J,Zuo D

Wed Dec 01 00:00:00 UTC 2021

USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.

The Journal of cell biology

Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J

Mon Jul 05 00:00:00 UTC 2021

Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.

Journal of agricultural and food chemistry

Liu H,Liang J,Zhong Y,Xiao G,Efferth T,Georgiev MI,Vargas-De-La-Cruz C,Bajpai VK,Caprioli G,Liu J,Lin J,Wu H,Peng L,Li Y,Ma L,Xiao J,Wang Q

Wed Nov 17 00:00:00 UTC 2021

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.

Acta neuropathologica communications

Rimal S,Li Y,Vartak R,Geng J,Tantray I,Li S,Huh S,Vogel H,Glabe C,Grinberg LT,Spina S,Seeley WW,Guo S,Lu B

Mon Oct 18 00:00:00 UTC 2021

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.

Acta neuropathologica communications

Rimal S,Li Y,Vartak R,Geng J,Tantray I,Li S,Huh S,Vogel H,Glabe C,Grinberg LT,Spina S,Seeley WW,Guo S,Lu B

Mon Oct 18 00:00:00 UTC 2021

Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis.

Frontiers in immunology

Tian Y,Huang B,Li J,Tian X,Zeng X

Thu Feb 24 00:00:00 UTC 2022

Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.

Molecular neurobiology

Liu H,Chen B,Guo B,Deng X,Wang B,Dou X

Wed Sep 01 00:00:00 UTC 2021

MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.

Pharmacological research

Xin D,Li T,Chu X,Ke H,Liu D,Wang Z

Mon Feb 01 00:00:00 UTC 2021

Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.

Cell death & disease

Yang J,Cao LL,Wang XP,Guo W,Guo RB,Sun YQ,Xue TF,Cai ZY,Ji J,Cheng H,Sun XL

Wed Jan 06 00:00:00 UTC 2021

Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.

Cell metabolism

Wang X,Wang H,Xu B,Huang D,Nie C,Pu L,Zajac GJM,Yan H,Zhao J,Shi F,Emmer BT,Lu J,Wang R,Dong X,Dai J,Zhou W,Wang C,Gao G,Wang Y,Willer C,Lu X,Zhu Y,Chen XW

Tue Feb 02 00:00:00 UTC 2021

Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.

Regenerative medicine

Fu G,Lu L,Pan Z,Fan A,Yin F

Thu Apr 01 00:00:00 UTC 2021

GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.

Theranostics

Guo S,Gu J,Ma J,Xu R,Wu Q,Meng L,Liu H,Li L,Xu Y

Fri Jan 28 00:00:00 UTC 2022

Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.

Annals of medicine

Deng Y,Tong J,Shi W,Tian Z,Yu B,Tang J

Wed Dec 01 00:00:00 UTC 2021

Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.

Glycobiology

Jia W,Zou X,Xu Z,Bai L,Shan A,Li Y,Shi J,Yang F,Ding C,Narimatsu H,Zhang Y

Thu Sep 09 00:00:00 UTC 2021

SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.

Journal of medical virology

Han L,Zhuang MW,Deng J,Zheng Y,Zhang J,Nan ML,Zhang XJ,Gao C,Wang PH

Wed Sep 01 00:00:00 UTC 2021

MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.

Frontiers in cardiovascular medicine

Yang W,Tu H,Tang K,Huang H,Ou S,Wu J

Wed Sep 08 00:00:00 UTC 2021

GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.

International journal of molecular sciences

Cerri S,Ghezzi C,Ongari G,Croce S,Avenali M,Zangaglia R,Di Monte DA,Valente EM,Blandini F

Tue Feb 23 00:00:00 UTC 2021

A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.

Scientific reports

Takahashi K,Niki T,Ogawa E,Fumika K,Nishioka Y,Sawa M,Arai H,Mukai K,Taguchi T

Mon Jun 07 00:00:00 UTC 2021

Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.

Journal of nanobiotechnology

Zheng H,Liang X,Han Q,Shao Z,Zhang Y,Shi L,Hong Y,Li W,Mai C,Mo Q,Fu Q,Ma X,Lin F,Li M,Hu B,Li X,Zhang Y

Thu Oct 21 00:00:00 UTC 2021

Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.

Neuromolecular medicine

Chiang CS,Fu SJ,Hsu CL,Jeng CJ,Tang CY,Huang YS,Tang SC

Wed Sep 01 00:00:00 UTC 2021

STING regulates BCR signaling in normal and malignant B cells.

Cellular & molecular immunology

Tang CA,Lee AC,Chang S,Xu Q,Shao A,Lo Y,Spalek WT,Pinilla-Ibarz JA,Del Valle JR,Hu CA

Thu Apr 01 00:00:00 UTC 2021

AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.

Nature communications

Mak HY,Ouyang Q,Tumanov S,Xu J,Rong P,Dong F,Lam SM,Wang X,Lukmantara I,Du X,Gao M,Brown AJ,Gong X,Shui G,Stocker R,Huang X,Chen S,Yang H

Thu Nov 25 00:00:00 UTC 2021

2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.

Metabolites

Zhao Y,He L,Wang T,Zhu L,Yan N

Mon Aug 23 00:00:00 UTC 2021

Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.

Journal of cellular and molecular medicine

Gao L,Nie X,Gou R,Hu Y,Dong H,Li X,Lin B

Wed Dec 01 00:00:00 UTC 2021

Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.

Ecotoxicology and environmental safety

Wang Y,Zhong Y,Sun K,Fan Y,Liao J,Wang G

Tue Jun 01 00:00:00 UTC 2021

Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.

Cells

Xie Y,Liu G,Zang X,Hu Q,Zhou C,Li Y,Liu D,Hong L

Fri Sep 03 00:00:00 UTC 2021

Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.

Human cell

Cheng L,Yu P,Li F,Jiang X,Jiao X,Shen Y,Lai X

Mon Nov 01 00:00:00 UTC 2021

Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.

Gene

Hua R,Wang Y,Lian W,Li W,Xi Y,Xue S,Kang T,Lei M

Fri Jan 15 00:00:00 UTC 2021

Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.

Rejuvenation research

Liu SJ,Meng MY,Han S,Gao H,Zhao YY,Yang Y,Lin ZY,Yang LR,Zhu K,Han R,Huang WW,Wang RQ,Yang LL,Wang WJ,Li L,Wang XD,Hou ZL,Liao LW,Yang L

Sun Aug 01 00:00:00 UTC 2021

Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.

Cell reports

Zhang X,Qu YY,Liu L,Qiao YN,Geng HR,Lin Y,Xu W,Cao J,Zhao JY

Tue Oct 12 00:00:00 UTC 2021

HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.

Cancer letters

Tong F,Mao X,Zhang S,Xie H,Yan B,Wang B,Sun J,Wei L

Thu May 28 00:00:00 UTC 2020

Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.

Frontiers in oncology

Wang X,Cheng K,Zhang G,Jia Z,Yu Y,Guo J,Hua Y,Guo F,Li X,Zou W,Sun H,Dong J,Yang Z

Fri Mar 29 00:00:00 UTC 2024

Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.

mBio

Sun Y,Zhang W,Dong C,Xiong S

Tue Dec 01 00:00:00 UTC 2020

Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.

mBio

Sun Y,Zhang W,Dong C,Xiong S

Tue Dec 01 00:00:00 UTC 2020

Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.

Environmental pollution (Barking, Essex : 1987)

Gao M,Dong Z,Sun J,Liu W,Xu M,Li C,Zhu P,Yang X,Shang X,Wu Y,Liu S

Sun Mar 01 00:00:00 UTC 2020

GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.

Scientific reports

Li X,Zhang Y,Zhang M,Wang Y

Wed Sep 30 00:00:00 UTC 2020

Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Xun C,Ge L,Tang F,Wang L,Zhuo Y,Long L,Qi J,Hu L,Duan D,Chen P,Lu M

Sun Nov 01 00:00:00 UTC 2020

Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.

Cancer letters

Li J,Liu X,Zang S,Zhou J,Zhang F,Sun B,Qi D,Li X,Kong J,Jin D,Yang X,Luo Y,Lu Y,Lin B,Niu W,Liu T

Sun Nov 01 00:00:00 UTC 2020

Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.

Journal of extracellular vesicles

Xu L,Faruqu FN,Liam-Or R,Abu Abed O,Li D,Venner K,Errington RJ,Summers H,Wang JT,Al-Jamal KT

Fri Jun 19 00:00:00 UTC 2020

Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.

Polymers

Ferrero-Andrés A,Closa D,Roselló-Catafau J,Folch-Puy E

Fri Dec 18 00:00:00 UTC 2020

Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.

Scientific reports

Zhao F,Cheng L,Shao Q,Chen Z,Lv X,Li J,He L,Sun Y,Ji Q,Lu P,Ji Y,Ji J

Fri Mar 06 00:00:00 UTC 2020

Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).

Cells

Duan TL,Jiao H,He GJ,Yan YB

Thu Jan 09 00:00:00 UTC 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.

Signal transduction and targeted therapy

Zheng Y,Zhuang MW,Han L,Zhang J,Nan ML,Zhan P,Kang D,Liu X,Gao C,Wang PH

Mon Dec 28 00:00:00 UTC 2020

Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.

Aging

Deng Q,Fang Q,Xie B,Sun H,Bao Y,Zhou S

Wed May 06 00:00:00 UTC 2020

USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.

Autophagy

Niu K,Fang H,Chen Z,Zhu Y,Tan Q,Wei D,Li Y,Balajee AS,Zhao Y

Wed Apr 01 00:00:00 UTC 2020

Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.

Frontiers in oncology

Ding XQ,Wang ZY,Xia D,Wang RX,Pan XR,Tong JH

Mon Sep 28 00:00:00 UTC 2020

SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.

Molecular biology of the cell

Amano G,Matsuzaki S,Mori Y,Miyoshi K,Han S,Shikada S,Takamura H,Yoshimura T,Katayama T

Sat Aug 15 00:00:00 UTC 2020

SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.

Journal of molecular medicine (Berlin, Germany)

Li N,Luo X,Yu Q,Yang P,Chen Z,Wang X,Jiang J,Xu J,Gong Q,Eizirik DL,Zhou Z,Zhao J,Xiong F,Zhang S,Wang CY

Tue Dec 01 00:00:00 UTC 2020

Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.

Aging

Yang D,Wang Q,Wei G,Wu J,Zhu YC,Zhu Q,Ni T,Liu X,Zhu YZ

Tue Nov 03 00:00:00 UTC 2020

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.

Nature communications

Song L,Liu Z,Hu HH,Yang Y,Li TY,Lin ZZ,Ye J,Chen J,Huang X,Liu DT,Zhou J,Shi Y,Zhao H,Xie C,Chen L,Song E,Lin SY,Lin SC

Tue Nov 17 00:00:00 UTC 2020

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.

Nature communications

Song L,Liu Z,Hu HH,Yang Y,Li TY,Lin ZZ,Ye J,Chen J,Huang X,Liu DT,Zhou J,Shi Y,Zhao H,Xie C,Chen L,Song E,Lin SY,Lin SC

Tue Nov 17 00:00:00 UTC 2020

Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.

OncoTargets and therapy

Yu Y,Luo Y,Fang Z,Teng W,Yu Y,Tian J,Guo P,Xu R,Wu J,Li Y

Sun Apr 17 00:00:00 UTC 2022

Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.

Medical science monitor : international medical journal of experimental and clinical research

Li M,Wang J,Fu L,Lu Y,Xu J,Zhou L,Zhu H,Fang L,Feng Z,Xie T,Zhou X

Sat Feb 15 00:00:00 UTC 2020

Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.

Acta biomaterialia

Xin D,Li T,Chu X,Ke H,Yu Z,Cao L,Bai X,Liu D,Wang Z

Tue Sep 01 00:00:00 UTC 2020

Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.

FASEB bioAdvances

Faruqu FN,Zhou S,Sami N,Gheidari F,Lu H,Al-Jamal KT

Wed Jul 01 00:00:00 UTC 2020

The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.

Taiwanese journal of obstetrics & gynecology

Zhang J,Yin H,Jiang H,Du X,Yang Z

Wed Jul 01 00:00:00 UTC 2020

Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8⁺ T cell response in tumor.

Science advances

Wang Y,Wang X,Cui X,Zhuo Y,Li H,Ha C,Xin L,Ren Y,Zhang W,Sun X,Ge L,Liu X,He J,Zhang T,Zhang K,Yao Z,Yang X,Yang J

Fri May 01 00:00:00 UTC 2020

Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8⁺ T cell response in tumor.

Science advances

Wang Y,Wang X,Cui X,Zhuo Y,Li H,Ha C,Xin L,Ren Y,Zhang W,Sun X,Ge L,Liu X,He J,Zhang T,Zhang K,Yao Z,Yang X,Yang J

Fri May 01 00:00:00 UTC 2020

Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.

Frontiers in cell and developmental biology

Tung SL,Fanelli G,Matthews RI,Bazoer J,Letizia M,Vizcay-Barrena G,Faruqu FN,Philippeos C,Hannen R,Al-Jamal KT,Lombardi G,Smyth LA

Wed Mar 17 00:00:00 UTC 2021

APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.

Cell reports

Uzureau S,Lecordier L,Uzureau P,Hennig D,Graversen JH,Homblé F,Mfutu PE,Oliveira Arcolino F,Ramos AR,La Rovere RM,Luyten T,Vermeersch M,Tebabi P,Dieu M,Cuypers B,Deborggraeve S,Rabant M,Legendre C,Moestrup SK,Levtchenko E,Bultynck G,Erneux C,Pérez-Morga D,Pays E

Tue Mar 17 00:00:00 UTC 2020

TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.

Molecular cell

An H,Ordureau A,Paulo JA,Shoemaker CJ,Denic V,Harper JW

Thu Jun 06 00:00:00 UTC 2019

Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.

Bioconjugate chemistry

Du Y,Hu H,Pei X,Du K,Wei T

Wed Mar 20 00:00:00 UTC 2019

Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.

Bioconjugate chemistry

Du Y,Hu H,Pei X,Du K,Wei T

Wed Mar 20 00:00:00 UTC 2019

Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.

Molecular reproduction and development

Lin Y,Liang A,He Y,Li Z,Li Z,Wang G,Sun F

Sun Sep 01 00:00:00 UTC 2019

Microglia as modulators of exosomal alpha-synuclein transmission.

Cell death & disease

Xia Y,Zhang G,Han C,Ma K,Guo X,Wan F,Kou L,Yin S,Liu L,Huang J,Xiong N,Wang T

Wed Feb 20 00:00:00 UTC 2019

Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.

The Journal of biological chemistry

Merriman C,Fu D

Fri Nov 08 00:00:00 UTC 2019

Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.

Stem cell research & therapy

Wang S,Su X,Xu M,Xiao X,Li X,Li H,Keating A,Zhao RC

Thu Apr 11 00:00:00 UTC 2019

Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.

International journal of molecular sciences

Wang J,Teng Y,Zhao G,Li F,Hou A,Sun B,Kong W,Gao F,Cai L,Jiang C

Wed Mar 27 00:00:00 UTC 2019

A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.

The Journal of biological chemistry

Shi J,Hu X,Guo Y,Wang L,Ji J,Li J,Zhang ZR

Fri Dec 27 00:00:00 UTC 2019

Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.

Research (Washington, D.C.)

Zheng D,Chen Y,Ai S,Zhang R,Gao Z,Liang C,Cao L,Chen Y,Hong Z,Shi Y,Wang L,Li X,Yang Z

Wed Sep 30 00:00:00 UTC 2020

Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.

International journal of biological sciences

Yan H,Gao Y,Ding Q,Liu J,Li Y,Jin M,Xu H,Ma S,Wang X,Zeng W,Chen Y

Tue Apr 07 00:00:00 UTC 2020

Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.

Journal of neuropathology and experimental neurology

McKay EC,Beck JS,Khoo SK,Dykema KJ,Cottingham SL,Winn ME,Paulson HL,Lieberman AP,Counts SE

Wed May 01 00:00:00 UTC 2019

Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.

Journal of cellular and molecular medicine

Hao L,Li S,Ma D,Chen S,Zhang B,Xiao D,Zhang J,Jiang N,Jiang S,Ma J

Sat Jun 01 00:00:00 UTC 2019

Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression.

Journal of virology

Bonenfant G,Williams N,Netzband R,Schwarz MC,Evans MJ,Pager CT

Sat Jun 15 00:00:00 UTC 2019

Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.

Methods in molecular biology (Clifton, N.J.)

Bersuker K,Olzmann JA

Wed Mar 11 00:00:00 UTC 2020

Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.

International journal of molecular medicine

Cui Y,Wang Y,Liu G

Wed May 01 00:00:00 UTC 2019

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.

Cell metabolism

Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC

Tue Apr 03 00:00:00 UTC 2018

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.

Cell metabolism

Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC

Tue Apr 03 00:00:00 UTC 2018

A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.

The Journal of allergy and clinical immunology

Tesi B,Rascon J,Chiang SCC,Burnyte B,Löfstedt A,Fasth A,Heizmann M,Juozapaite S,Kiudeliene R,Kvedaraite E,Miseviciene V,Muleviciene A,Müller ML,Nordenskjöld M,Matuzeviciene R,Samaitiene R,Speckmann C,Stankeviciene S,Zekas V,Voss M,Ehl S,Vaiciene-Magistris N,Henter JI,Meeths M,Bryceson YT

Sun Jul 01 00:00:00 UTC 2018

A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.

The Journal of allergy and clinical immunology

Sun Jul 01 00:00:00 UTC 2018

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.

Developmental cell

Bersuker K,Peterson CWH,To M,Sahl SJ,Savikhin V,Grossman EA,Nomura DK,Olzmann JA

Mon Jan 08 00:00:00 UTC 2018

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.

Developmental cell

Bersuker K,Peterson CWH,To M,Sahl SJ,Savikhin V,Grossman EA,Nomura DK,Olzmann JA

Mon Jan 08 00:00:00 UTC 2018

In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.

Analytical chemistry

Zhang P,Dong B,Zeng E,Wang F,Jiang Y,Li D,Liu D

Tue Oct 02 00:00:00 UTC 2018

In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.

Analytical chemistry

Zhang P,Dong B,Zeng E,Wang F,Jiang Y,Li D,Liu D

Tue Oct 02 00:00:00 UTC 2018

Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.

Journal of virology

Xin X,Wang H,Han L,Wang M,Fang H,Hao Y,Li J,Zhang H,Zheng C,Shen C

Tue May 01 00:00:00 UTC 2018

Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.

Journal of virology

Xin X,Wang H,Han L,Wang M,Fang H,Hao Y,Li J,Zhang H,Zheng C,Shen C

Tue May 01 00:00:00 UTC 2018

Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.

Journal of molecular and cellular cardiology

Zhao N,Mi L,Zhang X,Xu M,Yu H,Liu Z,Liu X,Guan G,Gao W,Wang J

Tue May 01 00:00:00 UTC 2018

Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.

Journal of molecular and cellular cardiology

Zhao N,Mi L,Zhang X,Xu M,Yu H,Liu Z,Liu X,Guan G,Gao W,Wang J

Tue May 01 00:00:00 UTC 2018

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Molecular and cellular biology

Ganji R,Mukkavalli S,Somanji F,Raman M

Sun Jul 01 00:00:00 UTC 2018

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Molecular and cellular biology

Ganji R,Mukkavalli S,Somanji F,Raman M

Sun Jul 01 00:00:00 UTC 2018

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Molecular and cellular biology

Ganji R,Mukkavalli S,Somanji F,Raman M

Sun Jul 01 00:00:00 UTC 2018

The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.

Molecular and cellular biology

Ganji R,Mukkavalli S,Somanji F,Raman M

Sun Jul 01 00:00:00 UTC 2018

A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.

Molecular biology of the cell

Huang EY,To M,Tran E,Dionisio LTA,Cho HJ,Baney KLM,Pataki CI,Olzmann JA

Tue May 01 00:00:00 UTC 2018

A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.

Molecular biology of the cell

Huang EY,To M,Tran E,Dionisio LTA,Cho HJ,Baney KLM,Pataki CI,Olzmann JA

Tue May 01 00:00:00 UTC 2018

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Nature communications

Li TY,Song L,Sun Y,Li J,Yi C,Lam SM,Xu D,Zhou L,Li X,Yang Y,Zhang CS,Xie C,Huang X,Shui G,Lin SY,Reue K,Lin SC

Tue May 15 00:00:00 UTC 2018

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Nature communications

Li TY,Song L,Sun Y,Li J,Yi C,Lam SM,Xu D,Zhou L,Li X,Yang Y,Zhang CS,Xie C,Huang X,Shui G,Lin SY,Reue K,Lin SC

Tue May 15 00:00:00 UTC 2018

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Nature communications

Li TY,Song L,Sun Y,Li J,Yi C,Lam SM,Xu D,Zhou L,Li X,Yang Y,Zhang CS,Xie C,Huang X,Shui G,Lin SY,Reue K,Lin SC

Tue May 15 00:00:00 UTC 2018

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.

Nature communications

Li TY,Song L,Sun Y,Li J,Yi C,Lam SM,Xu D,Zhou L,Li X,Yang Y,Zhang CS,Xie C,Huang X,Shui G,Lin SY,Reue K,Lin SC

Tue May 15 00:00:00 UTC 2018

Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.

Journal of experimental & clinical cancer research : CR

Zhou X,Yan T,Huang C,Xu Z,Wang L,Jiang E,Wang H,Chen Y,Liu K,Shao Z,Shang Z

Wed Oct 03 00:00:00 UTC 2018

Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.

Journal of experimental & clinical cancer research : CR

Zhou X,Yan T,Huang C,Xu Z,Wang L,Jiang E,Wang H,Chen Y,Liu K,Shao Z,Shang Z

Wed Oct 03 00:00:00 UTC 2018

Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.

Biophysics reports

Li M,Du W,Zhou M,Zheng L,Song E,Hou J

Wed Mar 30 00:00:00 UTC 2022

Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Song M,Han L,Chen FF,Wang D,Wang F,Zhang L,Wang ZH,Zhong M,Tang MX,Zhang W

Fri Sep 14 00:00:00 UTC 2018

Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Song M,Han L,Chen FF,Wang D,Wang F,Zhang L,Wang ZH,Zhong M,Tang MX,Zhang W

Fri Sep 14 00:00:00 UTC 2018

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 UTC 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Nature immunology

Sasai M,Sakaguchi N,Ma JS,Nakamura S,Kawabata T,Bando H,Lee Y,Saitoh T,Akira S,Iwasaki A,Standley DM,Yoshimori T,Yamamoto M

Tue Aug 01 00:00:00 UTC 2017

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.

Nucleic acids research

Li P,Du J,Goodier JL,Hou J,Kang J,Kazazian HH,Zhao K,Yu XF

Fri May 05 00:00:00 UTC 2017

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.

Nucleic acids research

Li P,Du J,Goodier JL,Hou J,Kang J,Kazazian HH,Zhao K,Yu XF

Fri May 05 00:00:00 UTC 2017

Protein kinase D at the Golgi controls NLRP3 inflammasome activation.

The Journal of experimental medicine

Zhang Z,Meszaros G,He WT,Xu Y,de Fatima Magliarelli H,Mailly L,Mihlan M,Liu Y,Puig Gámez M,Goginashvili A,Pasquier A,Bielska O,Neven B,Quartier P,Aebersold R,Baumert TF,Georgel P,Han J,Ricci R

Mon Sep 04 00:00:00 UTC 2017

Protein kinase D at the Golgi controls NLRP3 inflammasome activation.

The Journal of experimental medicine

Zhang Z,Meszaros G,He WT,Xu Y,de Fatima Magliarelli H,Mailly L,Mihlan M,Liu Y,Puig Gámez M,Goginashvili A,Pasquier A,Bielska O,Neven B,Quartier P,Aebersold R,Baumert TF,Georgel P,Han J,Ricci R

Mon Sep 04 00:00:00 UTC 2017

Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.

Diabetes

De Franco E,Flanagan SE,Yagi T,Abreu D,Mahadevan J,Johnson MB,Jones G,Acosta F,Mulaudzi M,Lek N,Oh V,Petz O,Caswell R,Ellard S,Urano F,Hattersley AT

Sat Jul 01 00:00:00 UTC 2017

Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.

Diabetes

De Franco E,Flanagan SE,Yagi T,Abreu D,Mahadevan J,Johnson MB,Jones G,Acosta F,Mulaudzi M,Lek N,Oh V,Petz O,Caswell R,Ellard S,Urano F,Hattersley AT

Sat Jul 01 00:00:00 UTC 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 UTC 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 UTC 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 UTC 2017

Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.

Chemical research in toxicology

Liu Z,Wang Y,Wang Y,Dong W,Xia X,Song E,Song Y

Mon Oct 16 00:00:00 UTC 2017

Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.

Stem cell research & therapy

Komaki M,Numata Y,Morioka C,Honda I,Tooi M,Yokoyama N,Ayame H,Iwasaki K,Taki A,Oshima N,Morita I

Tue Oct 03 00:00:00 UTC 2017

Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.

Stem cell research & therapy

Komaki M,Numata Y,Morioka C,Honda I,Tooi M,Yokoyama N,Ayame H,Iwasaki K,Taki A,Oshima N,Morita I

Tue Oct 03 00:00:00 UTC 2017

REG3β modifies cell tumor function by impairing extracellular vesicle uptake.

Scientific reports

Bonjoch L,Gironella M,Iovanna JL,Closa D

Fri Jun 09 00:00:00 UTC 2017

REG3β modifies cell tumor function by impairing extracellular vesicle uptake.

Scientific reports

Bonjoch L,Gironella M,Iovanna JL,Closa D

Fri Jun 09 00:00:00 UTC 2017

DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.

Scientific reports

Ding J,Shao L,Yao Y,Tong X,Liu H,Yue S,Xie L,Cheng SY

Thu Jul 13 00:00:00 UTC 2017

DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.

Scientific reports

Ding J,Shao L,Yao Y,Tong X,Liu H,Yue S,Xie L,Cheng SY

Thu Jul 13 00:00:00 UTC 2017

Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.

The Journal of pathology

Bonjoch L,Casas V,Carrascal M,Closa D

Sat Oct 01 00:00:00 UTC 2016

Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.

The Journal of pathology

Bonjoch L,Casas V,Carrascal M,Closa D

Sat Oct 01 00:00:00 UTC 2016

Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.

Journal of proteomics

Zhou Y,Xiong L,Zhang Y,Yu R,Jiang X,Xu G

Tue Oct 04 00:00:00 UTC 2016

Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.

Journal of proteomics

Zhou Y,Xiong L,Zhang Y,Yu R,Jiang X,Xu G

Tue Oct 04 00:00:00 UTC 2016

Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.

Nature microbiology

Dong N,Niu M,Hu L,Yao Q,Zhou R,Shao F

Mon Dec 12 00:00:00 UTC 2016

Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.

Nature microbiology

Dong N,Niu M,Hu L,Yao Q,Zhou R,Shao F

Mon Dec 12 00:00:00 UTC 2016

Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.

Journal of experimental & clinical cancer research : CR

Wang X,Xu C,Hua Y,Sun L,Cheng K,Jia Z,Han Y,Dong J,Cui Y,Yang Z

Thu Dec 01 00:00:00 UTC 2016

Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.

Journal of experimental & clinical cancer research : CR

Wang X,Xu C,Hua Y,Sun L,Cheng K,Jia Z,Han Y,Dong J,Cui Y,Yang Z

Thu Dec 01 00:00:00 UTC 2016

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

International journal of molecular sciences

Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ

Thu Oct 27 00:00:00 UTC 2016

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

International journal of molecular sciences

Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ

Thu Oct 27 00:00:00 UTC 2016

Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.

Nature cell biology

Chen W,Wu J,Li L,Zhang Z,Ren J,Liang Y,Chen F,Yang C,Zhou Z,Su SS,Zheng X,Zhang Z,Zhong CQ,Wan H,Xiao M,Lin X,Feng XH,Han J

Wed Apr 01 00:00:00 UTC 2015

Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.

Nature cell biology

Chen W,Wu J,Li L,Zhang Z,Ren J,Liang Y,Chen F,Yang C,Zhou Z,Su SS,Zheng X,Zhang Z,Zhong CQ,Wan H,Xiao M,Lin X,Feng XH,Han J

Wed Apr 01 00:00:00 UTC 2015

Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.

Journal of chromatography. A

Yang XX,Xu F,Wang D,Yang ZW,Tan HR,Shang MY,Wang X,Cai SQ

Fri Sep 25 00:00:00 UTC 2015

Journal of chromatography. A

Yang XX,Xu F,Wang D,Yang ZW,Tan HR,Shang MY,Wang X,Cai SQ

Fri Sep 25 00:00:00 UTC 2015

Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.

Genetics

Jokinen R,Lahtinen T,Marttinen P,Myöhänen M,Ruotsalainen P,Yeung N,Shvetsova A,Kastaniotis AJ,Hiltunen JK,Öhman T,Nyman TA,Weiler H,Battersby BJ

Fri May 01 00:00:00 UTC 2015

Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.

Genetics

Jokinen R,Lahtinen T,Marttinen P,Myöhänen M,Ruotsalainen P,Yeung N,Shvetsova A,Kastaniotis AJ,Hiltunen JK,Öhman T,Nyman TA,Weiler H,Battersby BJ

Fri May 01 00:00:00 UTC 2015

IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.

Cellular microbiology

Zhu X,He Z,Yuan J,Wen W,Huang X,Hu Y,Lin C,Pan J,Li R,Deng H,Liao S,Zhou R,Wu J,Li J,Li M

Thu Jan 01 00:00:00 UTC 2015

IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.

Cellular microbiology

Zhu X,He Z,Yuan J,Wen W,Huang X,Hu Y,Lin C,Pan J,Li R,Deng H,Liao S,Zhou R,Wu J,Li J,Li M

Thu Jan 01 00:00:00 UTC 2015

Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.

Parasitology research

Mao Q,Xie Z,Wang X,Chen W,Ren M,Shang M,Lei H,Tian Y,Li S,Liang P,Chen T,Liang C,Xu J,Li X,Huang Y,Yu X

Sun Feb 01 00:00:00 UTC 2015

Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.

Parasitology research

Mao Q,Xie Z,Wang X,Chen W,Ren M,Shang M,Lei H,Tian Y,Li S,Liang P,Chen T,Liang C,Xu J,Li X,Huang Y,Yu X

Sun Feb 01 00:00:00 UTC 2015

Rab18 and a Rab18 GEF complex are required for normal ER structure.

The Journal of cell biology

Gerondopoulos A,Bastos RN,Yoshimura S,Anderson R,Carpanini S,Aligianis I,Handley MT,Barr FA

Mon Jun 09 00:00:00 UTC 2014

Rab18 and a Rab18 GEF complex are required for normal ER structure.

The Journal of cell biology

Gerondopoulos A,Bastos RN,Yoshimura S,Anderson R,Carpanini S,Aligianis I,Handley MT,Barr FA

Mon Jun 09 00:00:00 UTC 2014

Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.

Current oncology (Toronto, Ont.)

Haimiti A,Hailiman Y,Gulina A,Du J,Hao Z,Rong XL,Zainuer A,Qin W,Lalai S

Sat Feb 01 00:00:00 UTC 2014

Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.

Current oncology (Toronto, Ont.)

Haimiti A,Hailiman Y,Gulina A,Du J,Hao Z,Rong XL,Zainuer A,Qin W,Lalai S

Sat Feb 01 00:00:00 UTC 2014

Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.

Acta neuropathologica communications

Ota K,Obayashi M,Ozaki K,Ichinose S,Kakita A,Tada M,Takahashi H,Ando N,Eishi Y,Mizusawa H,Ishikawa K

Thu Sep 11 00:00:00 UTC 2014

Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.

Acta neuropathologica communications

Ota K,Obayashi M,Ozaki K,Ichinose S,Kakita A,Tada M,Takahashi H,Ando N,Eishi Y,Mizusawa H,Ishikawa K

Thu Sep 11 00:00:00 UTC 2014

ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.

Chemistry & biology

Tan YL,Genereux JC,Pankow S,Aerts JM,Yates JR,Kelly JW

Thu Aug 14 00:00:00 UTC 2014

ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.

Chemistry & biology

Tan YL,Genereux JC,Pankow S,Aerts JM,Yates JR,Kelly JW

Thu Aug 14 00:00:00 UTC 2014

PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.

PloS one

Luo Z,Dong X,Li Y,Zhang Q,Kim C,Song Y,Kang L,Liu Y,Wu K,Wu J

Mon Oct 06 00:00:00 UTC 2014

PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.

PloS one

Luo Z,Dong X,Li Y,Zhang Q,Kim C,Song Y,Kang L,Liu Y,Wu K,Wu J

Mon Oct 06 00:00:00 UTC 2014

Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.

Chinese medical journal

Shang Y,Wang F,Bai C,Huang Y,Zhao LJ,Yao XP,Li Q,Sun SH

Sat Jan 01 00:00:00 UTC 2011

Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.

Chinese medical journal

Shang Y,Wang F,Bai C,Huang Y,Zhao LJ,Yao XP,Li Q,Sun SH

Sat Jan 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: Calnexin; FLJ26570; IP90; Major histocompatibility complex class I antigen-binding protein p88; p88; p90

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Gene Aliases: 1110069N15Rik; AI988026; CANX; CNX; D11Ertd153e; IP90; P90

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UniProt ID: (Human) P27824, (Rat) P35565, (Mouse) P35564

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Entrez Gene ID: (Human) 821, (Rat) 29144, (Mouse) 12330

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Function(s)

glycoprotein binding calcium ion binding protein binding carbohydrate binding apolipoprotein binding ionotropic glutamate receptor binding poly(A) RNA binding unfolded protein binding metal ion binding

Process(es)

aging synaptic vesicle endocytosis chaperone-mediated protein folding clathrin-mediated endocytosis protein folding antigen processing and presentation of peptide antigen via MHC class I protein secretion antigen processing and presentation of exogenous peptide antigen via MHC class II protein folding in endoplasmic reticulum

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Calnexin Polyclonal Antibody

Calnexin Antibody (10427-2-AP) in ICC/IF

Product Details

10427-2-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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