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Product Details
13675-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Calpain 11 Fusion Protein Ag4668 (352-702 aa encoded by BC033733)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: YWHTTFYEG SWRRGSSAGG CRNHPGTFWT NPQFKISLPE GDDPEDDAEG NVVACTCLVA LMQKNWRHAR QQGAQLQTIG FVLYAVPKEF QNIQDVHLKK EFFTKYQDHG FSEIFTNSRE VSSQLRLPPG EYIIIPSTFE PHRDADFLLR VFTEKHSESW ELDEVNYAEQ LQEEKVSEDD MDQDFLHLFK IVAGEGKEIG VYELQRLLNR MAIKFKSFKT KGFGLDACRC MINLMDKDGS GKLGLLEFKI LWKKLKKWMD IFRECDQDHS GTLNSYEMRL VIEKAGIKLN NKVMQVLVAR YADDDLIIDF DSFISCFLRL KTMFTFFLTM DPKNTGHICL SLEQWLQMTM WG (352-702 aa encoded by BC033733)
Target Information
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium-activated neutral proteinase 11; calcium-activated neutral proteinase 11 {ECO:0000250|UniProtKB:Q9UMQ6}; calcium-dependent thiol protease; Calpain 11; calpain 11 {ECO:0000312|EMBL:AAH97256.1}; Calpain-11; CANP 11; CANP 11 {ECO:0000250|UniProtKB:Q9UMQ6}; capn11; capn11 {ECO:0000312|RGD:1302946}; HIP2; LIG
Gene Aliases: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6, (Rat) Q4V8Q1, (Mouse) Q6J756
Entrez Gene ID: (Human) 11131, (Rat) 408218, (Mouse) 268958
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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