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Calpain S1 Antibody (PA5-31110) in ICC/IF
Calpain S1 Polyclonal Antibody detects CAPNS1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: CAPNS1 protein stained by Calpain S1 Polyclonal Antibody (Product # PA5-31110) diluted at 1:500. Blue: Hoechst 33343 staining.
Product Details
PA5-31110
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Calpain S1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548584
Product Specific Information
Recommended positive controls: 293T.
Predicted reactivity: Mouse (89%), Pig (97%), Rabbit (96%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CANP small subunit; CDPS; CSS1; small pol
Gene Aliases: CALPAIN4; CANP; CANPS; CAPN4; CAPNS; CAPNS1; CDPS; CSS1
UniProt ID: (Human) P04632
Entrez Gene ID: (Human) 826
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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