Product References
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue.
Frontiers in cell and developmental biology
Yildiz B,Schiedt L,Mulaw M,Bockmann J,Jesse S,Lutz AK,Boeckers TM
MA3-913 was used in Western Blot and Immunohistochemistry to find significant differences in gene expression of ion channels crucial for muscle contraction and for molecules involved in calcium ion regulation.
Tue Sep 26 00:00:00 UTC 2023
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue.
Frontiers in cell and developmental biology
Yildiz B,Schiedt L,Mulaw M,Bockmann J,Jesse S,Lutz AK,Boeckers TM
MA3-913 was used in Western Blot and Immunohistochemistry to find significant differences in gene expression of ion channels crucial for muscle contraction and for molecules involved in calcium ion regulation.
Tue Sep 26 00:00:00 UTC 2023
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue.
Frontiers in cell and developmental biology
Yildiz B,Schiedt L,Mulaw M,Bockmann J,Jesse S,Lutz AK,Boeckers TM
MA3-913 was used in Western Blot and Immunohistochemistry to find significant differences in gene expression of ion channels crucial for muscle contraction and for molecules involved in calcium ion regulation.
Tue Sep 26 00:00:00 UTC 2023
Skeletal muscle overexpression of sAnk1.5 in transgenic mice does not predispose to type 2 diabetes.
Scientific reports
Pierantozzi E,Raucci L,Buonocore S,Rubino EM,Ding Q,Laurino A,Fiore F,Soldaini M,Chen J,Rossi D,Vangheluwe P,Chen H,Sorrentino V
MA3-913 was used in Western Blotting to indicate that sAnk1.5 overexpression in skeletal muscle does not predispose mice to T2D susceptibility.
Sat May 20 00:00:00 UTC 2023
Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice.
Physiological reports
Yamamoto H,Eshima H,Kakehi S,Kawamori R,Watada H,Tamura Y
MA3-913 was used in Western Blotting to suggest that fatigue resistance in slow-twitch dominant muscle is impaired in mice with T2DM.
Thu Sep 01 00:00:00 UTC 2022
Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice.
Physiological reports
Yamamoto H,Eshima H,Kakehi S,Kawamori R,Watada H,Tamura Y
MA3-913 was used in Western Blotting to suggest that fatigue resistance in slow-twitch dominant muscle is impaired in mice with T2DM.
Thu Sep 01 00:00:00 UTC 2022
Quantification of the calcium signaling deficit in muscles devoid of triadin.
PloS one
Manno C,Tammineni E,Figueroa L,Marty I,Ríos E
MA3-913 was used in Western Blotting to find higher resting cytosolic and lower SR-luminal [Ca2+], 40% lower calsequestrin expression, and more CaV1.1, RyR1 and SERCA1.
Wed Mar 09 00:00:00 UTC 2022
Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation.
American journal of human genetics
Wyckelsma VL,Venckunas T,Houweling PJ,Schlittler M,Lauschke VM,Tiong CF,Wood HD,Ivarsson N,Paulauskas H,Eimantas N,Andersson DC,North KN,Brazaitis M,Westerblad H
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Thu Mar 04 00:00:00 UTC 2021
Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans.
The Journal of physiology
Monti E,Reggiani C,Franchi MV,Toniolo L,Sandri M,Armani A,Zampieri S,Giacomello E,Sarto F,Sirago G,Murgia M,Nogara L,Marcucci L,Ciciliot S,Šimunic B,Pišot R,Narici MV
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Tue Jun 01 00:00:00 UTC 2021
Dietary nitrate supplementation increases diaphragm peak power in old mice.
The Journal of physiology
Kumar RA,Kelley RC,Hahn D,Ferreira LF
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Thu Oct 01 00:00:00 UTC 2020
Tissue-specific small heat shock protein 20 activation is not associated with traditional autophagy markers in Ossabaw swine with cardiometabolic heart failure.
American journal of physiology. Heart and circulatory physiology
Silva KAS,Leary EV,Olver TD,Domeier TL,Padilla J,Rector RS,Emter CA
MA3-913 was used in Western Blotting to show that the activation of HSPB6 is tissue specific and associated with variable states of downstream markers of autophagy in a unique preclinical swine model of cardiometabolic HF with potential relevance to HFpEF.
Sun Nov 01 00:00:00 UTC 2020
A chronic high-fat diet exacerbates contractile dysfunction with impaired intracellular Ca2+ release capacity in the skeletal muscle of aged mice.
Journal of applied physiology (Bethesda, Md. : 1985)
Eshima H,Tamura Y,Kakehi S,Kakigi R,Hashimoto R,Funai K,Kawamori R,Watada H
MA3-913 was used in Western Blotting to investigate skeletal muscle contractile function ex vivo and intracellular Ca2+ release in male C57BL/6J mice fed a low-fat diet (LFD) or a high-fat diet (HFD) for 4 or 20 mo.
Fri May 01 00:00:00 UTC 2020
Vitamin C and E Treatment Blunts Sprint Interval Training-Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans.
Antioxidants (Basel, Switzerland)
Wyckelsma VL,Venckunas T,Brazaitis M,Gastaldello S,Snieckus A,Eimantas N,Baranauskiene N,Subocius A,Skurvydas A,Pääsuke M,Gapeyeva H,Kaasik P,Pääsuke R,Jürimäe J,Graf BA,Kayser B,Place N,Andersson DC,Kamandulis S,Westerblad H
MA3-913 was used in Western Blotting to suggest that treatment with the antioxidants vitamin C and E blunts sprint interval training-induced cellular signalling in skeletal muscle of elderly individuals.
Thu Sep 17 00:00:00 UTC 2020
Vitamin C and E Treatment Blunts Sprint Interval Training-Induced Changes in Inflammatory Mediator-, Calcium-, and Mitochondria-Related Signaling in Recreationally Active Elderly Humans.
Antioxidants (Basel, Switzerland)
Wyckelsma VL,Venckunas T,Brazaitis M,Gastaldello S,Snieckus A,Eimantas N,Baranauskiene N,Subocius A,Skurvydas A,Pääsuke M,Gapeyeva H,Kaasik P,Pääsuke R,Jürimäe J,Graf BA,Kayser B,Place N,Andersson DC,Kamandulis S,Westerblad H
MA3-913 was used in Western Blotting to suggest that treatment with the antioxidants vitamin C and E blunts sprint interval training-induced cellular signalling in skeletal muscle of elderly individuals.
Thu Sep 17 00:00:00 UTC 2020
Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes.
eLife
Tammineni ER,Kraeva N,Figueroa L,Manno C,Ibarra CA,Klip A,Riazi S,Rios E
MA3-913 was used in Immunohistochemistry to reveal that Malignant Hyperthermia Susceptibility entails a wide-ranging, pathogenic change in glucose metabolism.
Mon May 04 00:00:00 UTC 2020
Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes.
eLife
Tammineni ER,Kraeva N,Figueroa L,Manno C,Ibarra CA,Klip A,Riazi S,Rios E
MA3-913 was used in Immunohistochemistry to reveal that Malignant Hyperthermia Susceptibility entails a wide-ranging, pathogenic change in glucose metabolism.
Mon May 04 00:00:00 UTC 2020
Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes.
eLife
Tammineni ER,Kraeva N,Figueroa L,Manno C,Ibarra CA,Klip A,Riazi S,Rios E
MA3-913 was used in Immunohistochemistry to reveal that Malignant Hyperthermia Susceptibility entails a wide-ranging, pathogenic change in glucose metabolism.
Mon May 04 00:00:00 UTC 2020
Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes.
eLife
Tammineni ER,Kraeva N,Figueroa L,Manno C,Ibarra CA,Klip A,Riazi S,Rios E
MA3-913 was used in Immunohistochemistry to reveal that Malignant Hyperthermia Susceptibility entails a wide-ranging, pathogenic change in glucose metabolism.
Mon May 04 00:00:00 UTC 2020
Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice.
Human molecular genetics
Tinklenberg JA,Siebers EM,Beatka MJ,Meng H,Yang L,Zhang Z,Ross JA,Ochala J,Morris C,Owens JM,Laing NG,Nowak KJ,Lawlor MW
MA3-913 was used in Western Blotting to evaluate the effects of mRK35 treatment in the TgACTA1D286G mouse model of nemaline myopathy.
Thu Feb 15 00:00:00 UTC 2018
Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle.
Cell reports
Maurya SK,Herrera JL,Sahoo SK,Reis FCG,Vega RB,Kelly DP,Periasamy M
MA3-913 was used in Western Blotting to study the molecular basis of how sarcolipin uncoupling of SERCA regulates muscle oxidative metabolism.
Tue Sep 11 00:00:00 UTC 2018
Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice.
Human molecular genetics
Ravel-Chapuis A,Bélanger G,Côté J,Michel RN,Jasmin BJ
MA3-913 was used in Western Blotting to show that calcium-CnA signaling is hyperactivated in DM1 muscle and that such hyperactivation represents a beneficial compensatory adaptation to the disease.
Thu Jun 15 00:00:00 UTC 2017
Identification and characterization of three novel mutations in the CASQ1 gene in four patients with tubular aggregate myopathy.
Human mutation
Barone V,Del Re V,Gamberucci A,Polverino V,Galli L,Rossi D,Costanzi E,Toniolo L,Berti G,Malandrini A,Ricci G,Siciliano G,Vattemi G,Tomelleri G,Pierantozzi E,Spinozzi S,Volpi N,Fulceri R,Battistutta R,Reggiani C,Sorrentino V
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Immunocytochemistry
Fri Dec 01 00:00:00 UTC 2017
Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle.
Physiological reports
Eshima H,Tamura Y,Kakehi S,Kurebayashi N,Murayama T,Nakamura K,Kakigi R,Okada T,Sakurai T,Kawamori R,Watada H
MA3913 was used in western blot to report the effects of short- and long-term high-fat diets on fast-twitch skeletal muscles
Sat Apr 01 00:00:00 UTC 2017
Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle.
Physiological reports
Eshima H,Tamura Y,Kakehi S,Kurebayashi N,Murayama T,Nakamura K,Kakigi R,Okada T,Sakurai T,Kawamori R,Watada H
MA3913 was used in western blot to report the effects of short- and long-term high-fat diets on fast-twitch skeletal muscles
Sat Apr 01 00:00:00 UTC 2017
Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice.
The Journal of biological chemistry
Bal NC,Singh S,Reis FCG,Maurya SK,Pani S,Rowland LA,Periasamy M
MA3-913 was used in Immunohistochemistry to investigate the interplay between skeletal muscle- and brown adipose tissue-based thermogenesis under mild versus severe cold adaptation in mice.
Fri Oct 06 00:00:00 UTC 2017
Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice.
The Journal of biological chemistry
Bal NC,Singh S,Reis FCG,Maurya SK,Pani S,Rowland LA,Periasamy M
MA3-913 was used in Immunohistochemistry to investigate the interplay between skeletal muscle- and brown adipose tissue-based thermogenesis under mild versus severe cold adaptation in mice.
Fri Oct 06 00:00:00 UTC 2017
Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice.
The Journal of biological chemistry
Bal NC,Singh S,Reis FCG,Maurya SK,Pani S,Rowland LA,Periasamy M
MA3-913 was used in Immunohistochemistry to investigate the interplay between skeletal muscle- and brown adipose tissue-based thermogenesis under mild versus severe cold adaptation in mice.
Fri Oct 06 00:00:00 UTC 2017
Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.
PloS one
Fajardo VA,Gamu D,Mitchell A,Bloemberg D,Bombardier E,Chambers PJ,Bellissimo C,Quadrilatero J,Tupling AR
MA3913 was used in western blot to report the physiological role of sarcolipin upregulation in muscle myopathy
Wed Sep 06 00:00:00 UTC 2017
Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function.
The Journal of biological chemistry
Bal NC,Maurya SK,Singh S,Wehrens XH,Periasamy M
MA3-913 was used in western blot to study affects of acute minimization of brown adipose tissue function by increased reliance on muscle based thermogenesis
Fri Aug 12 00:00:00 UTC 2016
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding.
Frontiers in physiology
De Andrade PB,Neff LA,Strosova MK,Arsenijevic D,Patthey-Vuadens O,Scapozza L,Montani JP,Ruegg UT,Dulloo AG,Dorchies OM
MA3-913 was used in western blot to study the effects of caloric restriction skeletal muscle contraction, thyroid hormone metabolism, and fiber composition upon refeeding
Wed Oct 07 00:00:00 UTC 2015
The stress protein/chaperone Grp94 counteracts muscle disuse atrophy by stabilizing subsarcolemmal neuronal nitric oxide synthase.
Antioxidants & redox signaling
Vitadello M,Gherardini J,Gorza L
MA3-913 was used in western blot to study the role of sarcolemmal nNOS in the mechanism by which Gpr94 protects against atrophy in a rat model of muscle disuse
Sun Jun 01 00:00:00 UTC 2014
A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates.
Human mutation
Rossi D,Vezzani B,Galli L,Paolini C,Toniolo L,Pierantozzi E,Spinozzi S,Barone V,Pegoraro E,Bello L,Cenacchi G,Vattemi G,Tomelleri G,Ricci G,Siciliano G,Protasi F,Reggiani C,Sorrentino V
MA3-913 was used in immunohistochemistry to study a missense mutation in the calsequestrin-1 gene discovered in a group of patients with a myopathy
Wed Oct 01 00:00:00 UTC 2014
A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates.
Human mutation
Rossi D,Vezzani B,Galli L,Paolini C,Toniolo L,Pierantozzi E,Spinozzi S,Barone V,Pegoraro E,Bello L,Cenacchi G,Vattemi G,Tomelleri G,Ricci G,Siciliano G,Protasi F,Reggiani C,Sorrentino V
MA3-913 was used in immunohistochemistry to study a missense mutation in the calsequestrin-1 gene discovered in a group of patients with a myopathy
Wed Oct 01 00:00:00 UTC 2014
Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging.
Journal of the Royal Society, Interface
Jayasinghe ID,Munro M,Baddeley D,Launikonis BS,Soeller C
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Immunofluorescence
Mon Oct 06 00:00:00 UTC 2014
Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum.
The Biochemical journal
Rossi D,Bencini C,Maritati M,Benini F,Lorenzini S,Pierantozzi E,Scarcella AM,Paolini C,Protasi F,Sorrentino V
MA3-913 was used in western blot to study three regions of triadin that are involved in its targeting to the sarcoplasmic reticulum junctional domain
Sat Mar 01 00:00:00 UTC 2014
Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor.
The Biochemical journal
Chen Y,Xue S,Zou J,Lopez JR,Yang JJ,Perez CF
MA3-913 was used in Western Blotting to suggest that the CLR region provides channels with unique functional properties that modulate the rate of passive SR Ca2+ leak and confer on RyR1 and RyR3 distinctive [Ca2+]rest regulatory properties.
Sun Jun 01 00:00:00 UTC 2014
Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia.
The Journal of physiology
Manno C,Figueroa L,Royer L,Pouvreau S,Lee CS,Volpe P,Nori A,Zhou J,Meissner G,Hamilton SL,Ríos E
MA3-913 was used in western blot to study myofibre Ca(2+) metabolism in a murine model of malignant hyperthermia
Sun Sep 15 00:00:00 UTC 2013
The anticancer drug tamoxifen counteracts the pathology in a mouse model of duchenne muscular dystrophy.
The American journal of pathology
Dorchies OM,Reutenauer-Patte J,Dahmane E,Ismail HM,Petermann O,Patthey- Vuadens O,Comyn SA,Gayi E,Piacenza T,Handa RJ,Décosterd LA,Ruegg UT
MA3-913 was used in western blot to study the beneficial effects of tamoxifen on muscle force and structure in a murine model of Duchenne muscular dystrophy
Fri Feb 01 00:00:00 UTC 2013
Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo.
Journal of cell science
Amoasii L,Hnia K,Chicanne G,Brech A,Cowling BS,Müller MM,Schwab Y,Koebel P,Ferry A,Payrastre B,Laporte J
MA3-913 was used in western blot to study the role of the phosphoinositide phosphatase myotublarin in the remodeling of skeletal muscle sarcoplasmic reticulum
Mon Apr 15 00:00:00 UTC 2013
Application of fluorescence two-dimensional difference in-gel electrophoresis as a proteomic biomarker discovery tool in muscular dystrophy research.
Biology
Carberry S,Zweyer M,Swandulla D,Ohlendieck K
MA3-913 was used in western blot to perform a comparative proteomic analysis of normal and dystrophic muscle using fluoresent difference in-gel electrophoresis
Mon Dec 02 00:00:00 UTC 2013
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.
Nature medicine
Bal NC,Maurya SK,Sopariwala DH,Sahoo SK,Gupta SC,Shaikh SA,Pant M,Rowland LA,Bombardier E,Goonasekera SA,Tupling AR,Molkentin JD,Periasamy M
MA3-913 was used in Western Blotting to suggest that Sarcolipin is an important mediator of muscle thermogenesis and whole-body energy metabolism.
Mon Oct 01 00:00:00 UTC 2012
Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?
Journal of cardiac failure
Middlekauff HR,Vigna C,Verity MA,Fonarow GC,Horwich TB,Hamilton MA,Shieh P,Tupling AR
MA3-913 was used in western blot to investigate the abnormalities of calcium handling proteins in skeletal and heart muscle during heart failure
Sat Sep 01 00:00:00 UTC 2012
Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis.
PloS one
Boncompagni S,Thomas M,Lopez JR,Allen PD,Yuan Q,Kranias EG,Franzini-Armstrong C,Perez CF
MA3-913 was used in western blot to study the roles of triadin and junctin in anchoring calsequestrin to the junctional sarcoplasmic reticulum and in Ca(2+) homeostasis using triadin/junctin (-/-) knockout mice
Tue Nov 13 00:00:00 UTC 2012
Functional expression of transgenic 1sDHPR channels in adult mammalian skeletal muscle fibres.
The Journal of physiology
DiFranco M,Tran P,Quiñonez M,Vergara JL
MA3-913 was used in western blot to investigate the effect of alpha1sDHPR overexpression on calcium signaling in muscle fibers
Tue Mar 15 00:00:00 UTC 2011
DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue.
Journal of proteomics
Donoghue P,Staunton L,Mullen E,Manning G,Ohlendieck K
MA3-913 was used in Western Blotting to investigate the fate of the aging rat muscle proteome.
Wed Jun 16 00:00:00 UTC 2010
Proteomic profiling of naturally protected extraocular muscles from the dystrophin-deficient mdx mouse.
Biochemical and biophysical research communications
Lewis C,Ohlendieck K
MA3-913 was used in western blot to conduct proteomic profiling of extraocular muscles in Duchenne muscular dystrophy mouse model
Fri Jun 11 00:00:00 UTC 2010
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology
Pertille A,de Carvalho CL,Matsumura CY,Neto HS,Marques MJ
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Mon Feb 01 00:00:00 UTC 2010
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology
Pertille A,de Carvalho CL,Matsumura CY,Neto HS,Marques MJ
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Mon Feb 01 00:00:00 UTC 2010
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology
Pertille A,de Carvalho CL,Matsumura CY,Neto HS,Marques MJ
Published figure using Calsequestrin monoclonal antibody (Product # MA3-913) in Western Blot
Mon Feb 01 00:00:00 UTC 2010
Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.
The Journal of biological chemistry
Eltit JM,Feng W,Lopez JR,Padilla IT,Pessah IN,Molinski TF,Fruen BR,Allen PD,Perez CF
MA3-913 was used in western blot to investigate the importance of triadins in the regulation of resting cytoplasmic calcium
Fri Dec 03 00:00:00 UTC 2010
Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.
The Journal of biological chemistry
Eltit JM,Feng W,Lopez JR,Padilla IT,Pessah IN,Molinski TF,Fruen BR,Allen PD,Perez CF
MA3-913 was used in western blot to investigate the importance of triadins in the regulation of resting cytoplasmic calcium
Fri Dec 03 00:00:00 UTC 2010
T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase.
Proceedings of the National Academy of Sciences of the United States of America
Al-Qusairi L,Weiss N,Toussaint A,Berbey C,Messaddeq N,Kretz C,Sanoudou D,Beggs AH,Allard B,Mandel JL,Laporte J,Jacquemond V,Buj-Bello A
MA3-913 was used in Western Blotting to study how a myotubularin deficiency affects the function of the excitation-contraction coupling machinery of muscle fibers in mice.
Tue Nov 03 00:00:00 UTC 2009
Altered contractility of skeletal muscle in mice deficient in titin's M-band region.
Journal of molecular biology
Ottenheijm CA,Hidalgo C,Rost K,Gotthardt M,Granzier H
MA3-913 was used in western blot to investigate the role of M-band region of titin in muscle contraction
Fri Oct 16 00:00:00 UTC 2009
Diltiazem and verapamil protect dystrophin-deficient muscle fibers of MDX mice from degeneration: a potential role in calcium buffering and sarcolemmal stability.
Muscle & nerve
Matsumura CY,Pertille A,Albuquerque TC,Santo Neto H,Marques MJ
MA3-913 was used in western blot to study the novel role of diltiazem and verapamil in calcium homeostasis and sarcolemmal stability
Sun Feb 01 00:00:00 UTC 2009
Triadin deletion induces impaired skeletal muscle function.
The Journal of biological chemistry
Oddoux S,Brocard J,Schweitzer A,Szentesi P,Giannesini B,Brocard J,Fauré J,Pernet-Gallay K,Bendahan D,Lunardi J,Csernoch L,Marty I
MA3-913 was used in western blot to study the role of triadin in skeletal muscle function
Fri Dec 11 00:00:00 UTC 2009
Reduced expression of sarcalumenin and related Ca2+ -regulatory proteins in aged rat skeletal muscle.
Experimental gerontology
O'Connell K,Gannon J,Doran P,Ohlendieck K
MA3-913 was used in western blot to investigate the expression of sarcalumenin and related calcium-regulatory proteins in rodent skeletal muscle during aging
Wed Oct 01 00:00:00 UTC 2008
Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.
The Journal of biological chemistry
Shen X,Franzini-Armstrong C,Lopez JR,Jones LR,Kobayashi YM,Wang Y,Kerrick WG,Caswell AH,Potter JD,Miller T,Allen PD,Perez CF
MA3-913 was used in western blot to investigate the role of triadins in intracellular calcium homeostasis and excitation-contraction coupling in skeletal muscle.
Fri Dec 28 00:00:00 UTC 2007
Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.
The Journal of biological chemistry
Shen X,Franzini-Armstrong C,Lopez JR,Jones LR,Kobayashi YM,Wang Y,Kerrick WG,Caswell AH,Potter JD,Miller T,Allen PD,Perez CF
MA3-913 was used in western blot to investigate the role of triadins in intracellular calcium homeostasis and excitation-contraction coupling in skeletal muscle.
Fri Dec 28 00:00:00 UTC 2007
Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.
The Journal of biological chemistry
Shen X,Franzini-Armstrong C,Lopez JR,Jones LR,Kobayashi YM,Wang Y,Kerrick WG,Caswell AH,Potter JD,Miller T,Allen PD,Perez CF
MA3-913 was used in western blot to investigate the role of triadins in intracellular calcium homeostasis and excitation-contraction coupling in skeletal muscle.
Fri Dec 28 00:00:00 UTC 2007
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
The Journal of biological chemistry
Phimister AJ,Lango J,Lee EH,Ernst-Russell MA,Takeshima H,Ma J,Allen PD,Pessah IN
MA3-913 was used in immunoprecipitation to investigate the physical interaction between junctophilin 1 and ryanodine receptor type 1.
Fri Mar 23 00:00:00 UTC 2007
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
The Journal of biological chemistry
Phimister AJ,Lango J,Lee EH,Ernst-Russell MA,Takeshima H,Ma J,Allen PD,Pessah IN
MA3-913 was used in immunoprecipitation to investigate the physical interaction between junctophilin 1 and ryanodine receptor type 1.
Fri Mar 23 00:00:00 UTC 2007
Reduced expression of regucalcin in young and aged mdx diaphragm indicates abnormal cytosolic calcium handling in dystrophin-deficient muscle.
Biochimica et biophysica acta
Doran P,Dowling P,Donoghue P,Buffini M,Ohlendieck K
MA3-913 was used in western blot to study the reduced regucalcin expression observed in diaphragm muscle in muscular dystrophy and the significance for calcium handling
Sat Apr 01 00:00:00 UTC 2006
Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function.
The Journal of biological chemistry
Rodriguez P,Mitton B,Waggoner JR,Kranias EG
MA3-913 was used in western blot to study the mechanism for cardiac contractility regulation
Fri Dec 15 00:00:00 UTC 2006
Microarray profiling of skeletal muscle sarcoplasmic reticulum proteins.
Biochimica et biophysica acta
Schulz JS,Palmer N,Steckelberg J,Jones SJ,Zeece MG
MA3-913 was used in western blot to investigate the skeletal muscle sarcoplasmic reticulum proteins through microarray analyses
Fri Sep 01 00:00:00 UTC 2006
Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto-Kakizaki rat.
European journal of cell biology
Mulvey C,Harno E,Keenan A,Ohlendieck K
MA3-913 was used in western blot to study the reduced expression of the dystrophin-dystroglycan complex and the syntrophin-NOS complex in skeletal muscle of type 2 diabetic rats and the significance for insulin resistance
Tue Nov 01 00:00:00 UTC 2005
Restricted distribution of mRNAs encoding a sarcoplasmic reticulum or transverse tubule protein in skeletal myofibers.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Nissinen M,Kaisto T,Salmela P,Peltonen J,Metsikkö K
MA3-913 was used in immunohistochemistry to investigate the distribution of CSQ and DHPR proteins and corresponding mRNAs during myogenic development
Tue Feb 01 00:00:00 UTC 2005
Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation.
Biochimica et biophysica acta
Donoghue P,Doran P,Dowling P,Ohlendieck K
MA3-913 was used in western blot to study the effects of chronic low frequency stimulation on the proteome of fast muscle fibres
Sun Sep 25 00:00:00 UTC 2005
Triadins are not triad-specific proteins: two new skeletal muscle triadins possibly involved in the architecture of sarcoplasmic reticulum.
The Journal of biological chemistry
Vassilopoulos S,Thevenon D,Rezgui SS,Brocard J,Chapel A,Lacampagne A,Lunardi J,Dewaard M,Marty I
MA3-913 was used in western blot to demonstrate the role of two new skeletal muscle triadins in sarcoplasmic reticulum structure.
Fri Aug 05 00:00:00 UTC 2005
Transcriptional changes following restoration of SERCA2a levels in failing rat hearts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Del Monte F,Dalal R,Tabchy A,Couget J,Bloch KD,Peterson R,Hajjar RJ
MA3-913 was used in western blot to characterize the effect of SERCA2a on transcriptional activity in failing rat hearts
Wed Sep 01 00:00:00 UTC 2004
Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals.
American journal of physiology. Heart and circulatory physiology
Yatani A,Kim SJ,Kudej RK,Wang Q,Depre C,Irie K,Kranias EG,Vatner SF,Vatner DE
MA3-913 was used in western blot to study mammalian hibernators' inborn cardioprotective functions during hibernation
Tue Jun 01 00:00:00 UTC 2004
Increased sensitivity of the ryanodine receptor to halothane-induced oligomerization in malignant hyperthermia-susceptible human skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985)
Glover L,Heffron JJ,Ohlendieck K
MA3-913 was used in western blot to investigate the importance of RyR2 complex formation in the development of a metabolic crisis in malignant hyperthermia
Thu Jan 01 00:00:00 UTC 2004
Drastic reduction of sarcalumenin in Dp427 (dystrophin of 427 kDa)-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy.
The Biochemical journal
Dowling P,Doran P,Ohlendieck K
MA3-913 was used in western blot to study the markedly reduced levels of sarcalumenin in Dp427-deficient muscle fibres and the pathological significance of the resulting abnormal Ca(2+) metabolism
Thu Apr 15 00:00:00 UTC 2004
Subproteomics analysis of Ca+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle.
European journal of biochemistry
Doran P,Dowling P,Lohan J,McDonnell K,Poetsch S,Ohlendieck K
MA3-913 was used in western blot to study the reduced expression of calsequestrin in dystrophic mouse skeletal muscle
Fri Oct 01 00:00:00 UTC 2004
Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan.
European journal of cell biology
Dowling P,Lohan J,Ohlendieck K
MA3-913 was used in western blot to study the relative preservation of beta-dystoglycan in extraocular and toe muscles as the reason of the mild dystrophic phenotype of these tissues in Dp427-defficient muscular dystrophy
Thu May 01 00:00:00 UTC 2003
Increased expression of the nicotinic acetylcholine receptor in stimulated muscle.
Biochemical and biophysical research communications
O'Reilly C,Pette D,Ohlendieck K
MA3-913 was used in western blot to study the effect of chronic low frequency stimulation on nicotinic acetylcholine receptor expression in skeletal muscle
Fri Jan 10 00:00:00 UTC 2003
Supramolecular calsequestrin complex.
European journal of biochemistry
Glover L,Quinn S,Ryan M,Pette D,Ohlendieck K
MA3-913 was used in western blot to investigate the formation of supramolecular calsequestrin complex
Sun Sep 01 00:00:00 UTC 2002
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure.
Circulation
del Monte F,Williams E,Lebeche D,Schmidt U,Rosenzweig A,Gwathmey JK,Lewandowski ED,Hajjar RJ
MA3-913 was used in western blot to study the effect of SERCA2a gene transfer into failing rodent hearts.
Tue Sep 18 00:00:00 UTC 2001
Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle.
American journal of physiology. Cell physiology
Thompson CB,Dorup I,Ahn J,Leong PK,McDonough AA
MA3-913 was used in western blot to investigate the role of glucocorticoids on sodium pump alpha (2)- and beta (1)-subunit abundance in muscle
Thu Mar 01 00:00:00 UTC 2001
Expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy.
American journal of physiology. Cell physiology
Hunter RB,Mitchell-Felton H,Essig DA,Kandarian SC
MA3-913 was used in western blot to study the expression of endoplasmic reticulum stress proteins during skeletal muscle disuse atrophy
Mon Oct 01 00:00:00 UTC 2001
Low-frequency stimulation of fast muscle affects the abundance of Ca(2+)-ATPase but not its oligomeric status.
Journal of applied physiology (Bethesda, Md. : 1985)
Harmon S,Froemming GR,Leisner E,Pette D,Ohlendieck K
MA3-913 was used in western blot to investigate the possible effects of stimulation-induced changes in the abundance of calcium pump on protein-protein interactions
Mon Jan 01 00:00:00 UTC 2001
Dynamic localization and clustering of dendritic Kv2.1 voltage-dependent potassium channels in developing hippocampal neurons.
Neuroscience
Antonucci DE,Lim ST,Vassanelli S,Trimmer JS
MA3-913 was used in immunocytochemistry to study the distribution of Kv2.1 channels in developing rat hippocampal neurons
Wed Feb 20 00:00:00 UTC 2002
Calsequestrin binds to monomeric and complexed forms of key calcium-handling proteins in native sarcoplasmic reticulum membranes from rabbit skeletal muscle.
Biochimica et biophysica acta
Glover L,Culligan K,Cala S,Mulvey C,Ohlendieck K
MA3-913 was used in western blot to study the binding of calcium handling proteins to calsequestrin in rabbit skeletal muscle sarcoplasmic reticulum membranes
Sat Dec 01 00:00:00 UTC 2001
Exogenous Ca2+-ATPase isoform effects on Ca2+ transients of embryonic chicken and neonatal rat cardiac myocytes.
The Journal of physiology
Cavagna M,O'Donnell JM,Sumbilla C,Inesi G,Klein MG
MA3-913 was used in western blot to investigate the role of calsequestrin during the regulation of calcium by sarco-endoplasmic reticulum calcium-ATPase in skeletal and cardiac muscle.
Sun Oct 01 00:00:00 UTC 2000
Exogenous Ca2+-ATPase isoform effects on Ca2+ transients of embryonic chicken and neonatal rat cardiac myocytes.
The Journal of physiology
Cavagna M,O'Donnell JM,Sumbilla C,Inesi G,Klein MG
MA3-913 was used in western blot to investigate the role of calsequestrin during the regulation of calcium by sarco-endoplasmic reticulum calcium-ATPase in skeletal and cardiac muscle.
Sun Oct 01 00:00:00 UTC 2000
A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function.
The Journal of cell biology
Moore RA,Nguyen H,Galceran J,Pessah IN,Allen PD
MA3-913 was used in western blot to characterize a transgenic myogenic cell line without functioning skeletal muscle ryanodine receptor.
Mon Feb 23 00:00:00 UTC 1998
Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans.
The American journal of physiology
Balagopal P,Rooyackers OE,Adey DB,Ades PA,Nair KS
MA3-913 was used in western blot to investigate the effects of age on the synthesis rate of myosin heavy chain and sarcoplasmic protein in humans
Wed Oct 01 00:00:00 UTC 1997
Analysis of excitation-contraction-coupling components in chronically stimulated canine skeletal muscle.
European journal of biochemistry
Ohlendieck K,Briggs FN,Lee KF,Wechsler AW,Campbell KP
MA3-913 was used in western blot to investigate the protein components of skeletal muscle membranes in canine muscle
Wed Dec 18 00:00:00 UTC 1991
