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Invitrogen
Cannabinoid Receptor 1 Polyclonal Antibody
FIGURE: 1 / 1
Cannabinoid Receptor 1 Antibody (PA5-142758) in WB
Western Blot analysis of Cannabinoid Receptor 1 in Rat Brain lysate (35 µg protein in RIPA buffer) using Cannabinoid Receptor 1 Polyclonal Antibody (Product # PA5-142758) at 0.3 µg/mL incubated for 1 hour. Detected by chemiluminescence.
Product Details
PA5-142758
Product Specifications
Species Reactivity
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-NITEFYNKSLSSFKE.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933404
Product Specific Information
Additional Information: This antibody is expected to recognize both reported isoforms (NP_057167.2; NP_149421.2).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-type cannabinoid receptor; Cannabinoid receptor 1; CB-R; CB1; CB1 receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1
Gene Aliases: Cnr1; Skr6; SKR6R
UniProt ID: (Rat) P20272
Entrez Gene ID: (Rat) 25248
positive regulation of acute inflammatory response to antigenic stimulus
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
spermatogenesis
axonal fasciculation
aging
response to nutrient
learning or memory
memory
positive regulation of neuron projection development
regulation of lipid metabolic process
sensory perception of pain
positive regulation of fever generation
negative regulation of fatty acid beta-oxidation
regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
negative regulation of mast cell activation
negative regulation of dopamine secretion
response to nicotine
cannabinoid signaling pathway
response to cocaine
glucose homeostasis
positive regulation of apoptotic process
negative regulation of ion transport
response to morphine
response to ethanol
negative regulation of action potential
negative regulation of blood pressure
positive regulation of blood pressure
regulation of insulin secretion
negative regulation of nitric-oxide synthase activity
regulation of synaptic transmission, glutamatergic
maternal process involved in female pregnancy
regulation of feeding behavior
regulation of penile erection
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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