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Product Details
PA5-142257
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-PRRKPQTRGKTFH (aa 405-417).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2932910
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carabin; EBP50-PDZ interactor of 64 kD; TBC1 domain family member 10C; TBC1 domain family, member 10C
Gene Aliases: 1810062O14Rik; AI428527; CARABIN; EPI64C; TBC1D10C
UniProt ID: (Human) Q8IV04, (Mouse) Q8C9V1
Entrez Gene ID: (Human) 374403, (Mouse) 108995
retrograde transport, endosome to Golgi
negative regulation of B cell activation
negative regulation of NFAT protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
intracellular protein transport
regulation of vesicle fusion
activation of GTPase activity
regulation of cilium assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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