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Product Details
PA5-31802
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Carabin. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549275
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Mouse (95%), Rat (96%), Rhesus Monkey (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carabin; TBC1 domain family member 10C; TBC1 domain family, member 10C
Gene Aliases: CARABIN; EPI64C; TBC1D10C
UniProt ID: (Human) Q8IV04
Entrez Gene ID: (Human) 374403
intracellular protein transport
regulation of vesicle fusion
retrograde transport, endosome to Golgi
negative regulation of B cell activation
negative regulation of NFAT protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
activation of GTPase activity
regulation of cilium assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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