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Invitrogen
Carbonic Anhydrase IV Recombinant Rabbit Monoclonal Antibody (039)
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Carbonic Anhydrase IV Antibody (MA5-29073) in IHC (P)
Immunohistochemical staining of human Carbonic Anhydrase IV in human lung with Carbonic Anhydrase IV Recombinant Rabbit Monoclonal Antibody (39) (Product # MA5-29073, 1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to pulmonary capillaries.
Product Details
MA5-29073
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
039
Immunogen
Recombinant Human Carbonic Anhydrase IV/CA4 protein (Met1-Lys283)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785003
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Carbonic Anhydrase IV/CA4.
Target Information
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV; carbonic dehydratase IV
Gene Aliases: CA4; CAIV; Car4; RP17
UniProt ID: (Human) P22748
Entrez Gene ID: (Human) 762
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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