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Invitrogen
Carbonic Anhydrase IV Monoclonal Antibody (310413)
FIGURE: 1 / 1
Carbonic Anhydrase IV Antibody (MA5-24028) in WB
Western blot analysis of Carbonic Anhydrase IV in Jurkat human acute T cell leukemia cell line and human lung tissue. Samples were incubated in Carbonic Anhydrase IV monoclonal antibody (Product # MA5-24028) using a dilution of 2 µg/mL followed by a HRP-conjugated Anti-Mouse IgG secondary antibody. A specific band was detected for Carbonic Anhydrase IV/CA4 at approximately 35 kDa (as indicated). This experi... View More
Product Details
MA5-24028
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
310413
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Carbonic AnhydraseIV/CA4 Ala19-Lys283
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609169
Product Specific Information
In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human (rh) CA1, rhCA2, and recombinant mouse CA4 is observed. This antibody does not cross-react with rhCA3, 8, 9, 10, 12, 13, or 14.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV; carbonic dehydratase IV
Gene Aliases: CA4; CAIV; Car4; RP17
UniProt ID: (Human) P22748
Entrez Gene ID: (Human) 762
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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