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Invitrogen
Carbonic Anhydrase XI Polyclonal Antibody
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FIGURE: 1 / 3
Carbonic Anhydrase XI Antibody (PA5-103704) in ICC/IF
Immunocytochemistry analysis of Carbonic Anhydrase XI in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Carbonic Anhydrase XI polyclonal antibody (Product # PA5-103704) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFl... View More
Product Details
PA5-103704
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CA11(Accession O75493), corresponding to amino acid residues Q274-V324.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853037
Product Specific Information
Antibody detects endogenous levels of total CA11.
Target Information
Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic Anhydrase XI participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Further, Carbonic Anhydrase XI show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-RP II; CA-RP XI; CA-XI; carbonic anhydrase XI; Carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI; carbonic anhydrase-related XI protein; CARP XI; CARP-2
Gene Aliases: CA11; CAR-XI; Car11; CARP2; CARPX1; UNQ211/PRO237
UniProt ID: (Human) O75493, (Mouse) O70354
Entrez Gene ID: (Human) 770, (Rat) 308588, (Mouse) 12348
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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