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Invitrogen
Carbonic Anhydrase XI Polyclonal Antibody
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Product Details
PA5-22339
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CA11. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.81 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152680
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Pig (96%), Sheep (97%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic Anhydrase XI participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Further, Carbonic Anhydrase XI show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA-RP II; CA-RP XI; CA-XI; carbonic anhydrase XI; Carbonic anhydrase-related protein 11; Carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI; CARP XI; CARP-2
Gene Aliases: CA11; CARP2; CARPX1; UNQ211/PRO237
UniProt ID: (Human) O75493
Entrez Gene ID: (Human) 770
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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