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Invitrogen
Caspase 6 (Cleaved Asp162) Polyclonal Antibody
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Caspase 6 (Cleaved Asp162) Antibody (PA5-119529) in IHC (P)
Immunohistochemistry of Caspase 6 (Cleaved Asp162) in paraffin-embedded rat esophagus. Sample was treated for antigen retrieval with Citrate buffer (pH 6.0, 15 min) and incubated with polyclonal Caspase 6 (Cleaved Asp162) antibody (Product # PA5-119529) at a dilution of 1:1000.
Product Details
PA5-119529
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Caspase 6 (cleaved Asp162). The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913103
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target Information
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptotic protease Mch-2; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; Caspase-6; MCH2
Gene Aliases: CASP-6; CASP6; MCH2
UniProt ID: (Human) P55212, (Mouse) O08738
Entrez Gene ID: (Human) 839, (Mouse) 12368, (Rat) 83584
lens development in camera-type eye
acute inflammatory response to non-antigenic stimulus
proteolysis
apoptotic process
response to heat
response to glucose
response to organic substance
response to metal ion
response to iron ion
response to organonitrogen compound
response to gamma radiation
epithelial cell differentiation
response to estradiol
response to testosterone
response to cytokine
response to hydrogen peroxide
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of retinal cell programmed cell death
cellular component disassembly involved in execution phase of apoptosis
regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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