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Product Details
BS-4094R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Cdc25B, amino acids 501-580.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Gene Aliases: AI604853; CDC25B; CDC25HU2; Cdc25m2
UniProt ID: (Human) P30305, (Mouse) P30306, (Rat) P48966
Entrez Gene ID: (Human) 994, (Mouse) 12531, (Rat) 171103
G2/M transition of mitotic cell cycle
mitotic cell cycle
oocyte maturation
protein phosphorylation
mitotic nuclear division
female meiosis I
positive regulation of cell proliferation
positive regulation of cytokinesis
peptidyl-tyrosine dephosphorylation
positive regulation of protein kinase activity
positive regulation of mitotic cell cycle
cell division
mitotic M phase
protein dephosphorylation
cell cycle
Performance Guarantee
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