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Antibody detects endogenous levels of total BORG4.
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: binder of Rho GTPase 4; Binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; MGC17125; MGC3740
Gene Aliases: 1500041M20Rik; BORG4; CDC42EP4; CEP4; KAIA1777
UniProt ID: (Human) Q9H3Q1, (Mouse) Q9JM96
Entrez Gene ID: (Human) 23580, (Mouse) 56699, (Rat) 303653
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