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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CDC42EP4 Antibodies

          Invitrogen

          Cdc42EP4 Polyclonal Antibody

          View all (11) CDC42EP4 antibodies

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          Datasheet
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          Cite Cdc42EP4 Polyclonal Antibody

          • Antibody Testing Data (5)
          Cdc42EP4 Antibody in Immunocytochemistry (ICC/IF)
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          Cdc42EP4 Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 5

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          Cdc42EP4 Antibody (PA5-54769) in ICC/IF

          Immunofluorecent analysis of Cdc42EP4 in human cell line U-2 OS using Cdc42EP4 Polyclonal Antibody (Product # PA5-54769). Staining shows localization to actin filaments and microtubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Cdc42EP4 Antibody in Immunocytochemistry (ICC/IF)
          Cdc42EP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cdc42EP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cdc42EP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cdc42EP4 Antibody in Immunohistochemistry (IHC)

          Product Details

          PA5-54769

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human Cdc42EP4. Recombinant protein control fragment (Product #RP-93478).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.4 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2639566

          Product Specific Information

          Immunogen sequence: RHTMHVGRAG DAFGDTSFLN SKAGEPDGES LDEQPSSSSS KRSLLSRKFR GSKRSQSVTR GEREQRDMLG SLRDSALFVK NAMSLPQLNE KEAAEKGTSK

          Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

          Target Information

          The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; MGC17125; MGC3740

          View more View less

          Gene Aliases: BORG4; CDC42EP4; CEP4; KAIA1777

          View more View less

          UniProt ID: (Human) Q9H3Q1

          View more View less

          Entrez Gene ID: (Human) 23580

          View more View less

          Function(s)
          GTPase activator activity protein binding GTP-Rho binding poly(A) RNA binding
          Process(es)
          Rho protein signal transduction regulation of cell shape positive regulation of actin filament polymerization positive regulation of pseudopodium assembly positive regulation of GTPase activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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