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Invitrogen
Cdc5L Recombinant Rabbit Monoclonal Antibody (1E3)
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FIGURE: 1 / 5
Cdc5L Antibody (MA5-49787) in ICC/IF
Immunocytochemistry analysis of A549 cells with Cdc5L monoclonal antibody (Product # MA5-49787) at 1:42, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Product Details
MA5-49787
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1E3
Immunogen
A synthesized peptide derived from human CDC5L
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3092614
Target Information
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; dJ319D22.1 (CDC5-like protein); hCDC5; Pombe cdc5-related protein
Gene Aliases: CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP
UniProt ID: (Human) Q99459
Entrez Gene ID: (Human) 988
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor recruiting
transcription corepressor binding
DNA binding
protein binding
protein phosphatase 1 binding
protein kinase binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
WD40-repeat domain binding
mitotic cell cycle
mRNA splicing, via spliceosome
DNA repair
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
cellular response to fibroblast growth factor stimulus
cellular response to interleukin-2
signal transduction involved in DNA damage checkpoint
cellular response to wortmannin
cellular response to nerve growth factor stimulus
cellular response to prolactin
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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