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Invitrogen
Chordin Polyclonal Antibody
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Chordin Antibody (PA5-109536) in WB
Western blot analysis of Chordin in extracts of various cell lines. Samples were incubated with Chordin Polyclonal antibody (Product # PA5-109536) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-109536
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 686-955 of human CHRD (NP_003732.2).
Conjugate
Form
Liquid
Concentration
1.32 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2854947
Product Specific Information
Immunogen sequence: PALAPAKPGG PGRPRDPNTC FFEGQQRPHG ARWAPNYDPL CSLCTCQRRT VICDPVVCPP PSCPHPVQAP DQCCPVCPEK QDVRDLPGLP RSRDPGEGCY FDGDRSWRAA GTRWHPVVPP FGLIKCAVCT CKGGTGEVHC EKVQCPRLAC AQPVRVNPTD CCKQCPVGSG AHPQLGDPMQ ADGPRGCRFA GQWFPESQSW HPSVPPFGEM SCITCRCGAG VPHCERDDCS LPLSCGSGKE SRCCSRCTAH RRPAPETRTD PELEKEAEGS
Target Information
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chordin
Gene Aliases: Chd; Chrd
UniProt ID: (Mouse) Q9Z0E2
Entrez Gene ID: (Rat) 117275, (Mouse) 12667
skeletal system development
osteoblast differentiation
gastrulation with mouth forming second
mesoderm formation
positive regulation of mesenchymal cell proliferation
pattern specification process
central nervous system development
dorsal/ventral pattern formation
BMP signaling pathway involved in spinal cord dorsal/ventral patterning
negative regulation of cell migration
negative regulation of BMP signaling pathway
forebrain development
negative regulation of osteoblast differentiation
positive regulation of cell adhesion
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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