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Invitrogen
Chordin Recombinant Rabbit Monoclonal Antibody (065)
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Product Details
MA5-43081
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
065
Immunogen
A synthetic peptide corresponding to the center region of the Human chordin
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912221
Product Specific Information
Specificity: Human chordin
Target Information
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chordin
Gene Aliases: CHRD; UNQ217/PRO243
UniProt ID: (Human) Q9H2X0
Entrez Gene ID: (Human) 8646
skeletal system development
osteoblast differentiation
gastrulation with mouth forming second
mesoderm formation
positive regulation of mesenchymal cell proliferation
BMP signaling pathway involved in spinal cord dorsal/ventral patterning
negative regulation of cell migration
negative regulation of BMP signaling pathway
forebrain development
floor plate development
negative regulation of osteoblast differentiation
positive regulation of cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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