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Chromogranin B Polyclonal Antibody

Chromogranin B Antibody in Immunocytochemistry (ICC/IF)

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Chromogranin B Antibody (14968-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed PC-12 cells using Chromogranin B antibody (Product # 14968-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Chromogranin B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Chromogranin B Antibody in Western Blot (WB)

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Product Details

14968-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Chromogranin B Fusion Protein Ag6833 (328-677 aa encoded by BC000375)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: HSTHYRASE EEPEYGEEIK GYPGVQAPED LEWERYRGRG SEEYRAPRPQ SEESWDEEDK RNYPSLELDK MAHGYGEESE EERGLEPGKG RHHRGRGGEP RAYFMSDTRE EKRFLGEGHH RVQENQMDKA RRHPQGAWKE LDRNYLNYGE EGAPGKWQQQ GDLQDTKENR EEARFQDKQY SSHHTAEKRK RLGELFNPYY DPLQWKSSHF ERRDNMNDNF LEGEEENELT LNEKNFFPEY NYDWWEKKPF SEDVNWGYEK RNLARVPKLD LKRQYDRVAQ LDQLLHYRKK SAEFPDFYDS EEPVSTHQEA ENEKDRADQT VLTEDEKKEL ENLAAMDLEL QKIAEKFSQR G (328-677 aa encoded by BC000375)

Target Information

Chromogranin B is a tyrosine sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Chromogranin functions as a neuroendocrine secretory granule protein which may be the precursor for other biologically active peptides.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Famsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796.

Cell research

Long A,Liu Y,Fang X,Jia L,Li Z,Hu J,Wu S,Chen C,Huang P,Wang Y

Sat Apr 01 00:00:00 UTC 2023

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo.

Diabetes

Davidson RK,Kanojia S,Wu W,Kono T,Xu J,Osmulski M,Bone RN,Casey N,Evans-Molina C,Sims EK,Spaeth JM

Thu Jun 01 00:00:00 UTC 2023

Citrobacter rodentium Infection Induces Persistent Molecular Changes and Interferon Gamma-Dependent Major Histocompatibility Complex Class II Expression in the Colonic Epithelium.

mBio

Mullineaux-Sanders C,Kozik Z,Sanchez-Garrido J,Hopkins EGD,Choudhary JS,Frankel G

Mon Feb 22 00:00:00 UTC 2021

Kaposi's Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells.

Journal of virology

Valiya Veettil M,Krishna G,Roy A,Ghosh A,Dutta D,Kumar B,Chakraborty S,Anju TR,Sharma-Walia N,Chandran B

Tue Mar 31 00:00:00 UTC 2020

Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells.

Journal of cell science

Bearrows SC,Bauchle CJ,Becker M,Haldeman JM,Swaminathan S,Stephens SB

Mon Jul 01 00:00:00 UTC 2019

Identification of proteins that bind to the neuroprotective agent neoechinulin A.

Bioscience, biotechnology, and biochemistry

Kamisuki S,Himeno N,Tsurukawa Y,Kusayanagi T,Takeno M,Kamakura T,Kuramochi K,Sugawara F

Thu Mar 01 00:00:00 UTC 2018

Identification of proteins that bind to the neuroprotective agent neoechinulin A.

Bioscience, biotechnology, and biochemistry

Kamisuki S,Himeno N,Tsurukawa Y,Kusayanagi T,Takeno M,Kamakura T,Kuramochi K,Sugawara F

Thu Mar 01 00:00:00 UTC 2018

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

Journal of proteome research

Collins MA,An J,Hood BL,Conrads TP,Bowser RP

Fri Nov 06 00:00:00 UTC 2015

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis.

Journal of proteome research

Collins MA,An J,Hood BL,Conrads TP,Bowser RP

Fri Nov 06 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: CgB; Chromogranin-B; secretogranin B; Secretogranin I; Secretogranin-1; SgI

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Gene Aliases: CHGB; Scg-1; SCG1

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UniProt ID: (Human) P05060, (Mouse) P16014

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Entrez Gene ID: (Human) 1114, (Mouse) 12653

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Function(s)

protein binding hormone activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Chromogranin B Polyclonal Antibody

Chromogranin B Antibody (14968-1-AP) in ICC/IF

Product Details

14968-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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