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Invitrogen
Chromogranin C Polyclonal Antibody
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Chromogranin C Antibody (PA5-30718) in IHC (P)
Chromogranin C Polyclonal Antibody detects Chromogranin C protein at membrane on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. Chromogranin C Polyclonal Antibody (Product # PA5-30718) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-30718
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human Chromogranin C. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548192
Product Specific Information
Recommended positive controls: IMR32, U87-MG, mouse brain, rat brain.
Predicted reactivity: Mouse (89%), Rat (88%), Pig (88%), Rhesus Monkey (96%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chromogranin-C; Secretogranin II; Secretogranin-2; secretoneurin; SgII
Gene Aliases: CHGC; EM66; Scg-2; SCG2; SgII; SN
UniProt ID: (Human) P13521, (Mouse) Q03517
Entrez Gene ID: (Human) 7857, (Mouse) 20254
MAPK cascade
angiogenesis
positive regulation of endothelial cell proliferation
intracellular signal transduction
eosinophil chemotaxis
positive chemotaxis
induction of positive chemotaxis
negative regulation of endothelial cell apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of endothelial cell proliferation
inflammatory response
protein secretion
endothelial cell migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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