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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Claudin-11 is an oligodendrocyte-specific protein that is expressed in the tight junctions of Sertoli cells and myelin sheaths in mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Claudin-11; Oligodendrocyte transmembrane protein; Oligodendrocyte-specific protein
Gene Aliases: Claudin-11; Claudin11; CLDN11; OSP; OTM
UniProt ID: (Human) O75508, (Mouse) Q60771
Entrez Gene ID: (Human) 5010, (Mouse) 18417, (Rat) 84588
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