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The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands.
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Protein Aliases: Claudin-12
Gene Aliases: CLDN12
UniProt ID: (Human) P56749
Entrez Gene ID: (Human) 9069
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