Product References
Na/K-ATPase signaling tonically inhibits sodium reabsorption in the renal proximal tubule.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mukherji ST,Brambilla L,Stuart KB,Mayes I,Kutz LC,Chen Y,Barbosa LA,Elmadbouh I,McDermott JP,Haller ST,Romero MF,Soleimani M,Liu J,Shapiro JI,Blanco GV,Xie Z,Pierre SV
51-6100 was used in Western Blot to study NKA signaling inhibition on Na+ reabsorption by regulating key apical and basolateral Na+ transporters.
Sat Apr 01 00:00:00 UTC 2023
EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier.
The Journal of cell biology
Higashi T,Saito AC,Fukazawa Y,Furuse M,Higashi AY,Ono M,Chiba H
51-6100 was used in Immunocytochemistry-immunofluorescence to reveal a novel mechanism of TJ maintenance through the localized proteolysis of EpCAM at TJ leaks, and provide a better understanding of the dynamic regulation of epithelial permeability.
Mon Jan 02 00:00:00 UTC 2023
Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing.
International journal of molecular sciences
Wittner L,Wagener L,Wiese JJ,Stolzer I,Krug SM,Naschberger E,Jackstadt R,Beyaert R,Atreya R,Kühl AA,Sturm G,Gonzalez-Acera M,Patankar JV,Becker C,Siegmund B,Trajanoski Z,Winner B,Neurath MF,Schumann M,Günther C
51-6100 was used in Immunocytochemistry to suggest that the protease function of MALT1 plays a critical role in the regulation of immune and inflammatory responses, as well as mucosal healing.
Mon Apr 17 00:00:00 UTC 2023
Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M).
Cells
Awad K,Barmeyer C,Bojarski C,Nagel O,Lee IM,Schweiger MR,Schulzke JD,Bücker R
51-6100 was used in Western Blotting to investigate the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type IBS.
Thu Jan 05 00:00:00 UTC 2023
Digested Cinnamon (Cinnamomum verum J. Presl) Bark Extract Modulates Claudin-2 Gene Expression and Protein Levels under TNFα/IL-1β Inflammatory Stimulus.
International journal of molecular sciences
Lonati E,Sala G,Corbetta P,Pagliari S,Cazzaniga E,Botto L,Rovellini P,Bruni I,Palestini P,Bulbarelli A
51-6100 was used in Western Blotting to show that pre-treatment with cinnamon extract prevents TEER loss by claudin-2 protein level regulation, influencing both gene transcription and autophagy-mediated degradation.
Wed May 24 00:00:00 UTC 2023
Mucin-degrading gut commensals isolated from healthy faecal donor suppress intestinal epithelial inflammation and regulate tight junction barrier function.
Frontiers in immunology
Pan M,Barua N,Ip M
51-6100 was used in Immunocytochemistry-immunofluorescence to indicate that mucin-degrading gut commensals were widely distributed in the gut microbiota and showed anti-inflammatory effect against pathogen infection and potential in modulating the epithelial barrier function.
Tue Nov 01 00:00:00 UTC 2022
Mucin-degrading gut commensals isolated from healthy faecal donor suppress intestinal epithelial inflammation and regulate tight junction barrier function.
Frontiers in immunology
Pan M,Barua N,Ip M
51-6100 was used in Immunocytochemistry-immunofluorescence to indicate that mucin-degrading gut commensals were widely distributed in the gut microbiota and showed anti-inflammatory effect against pathogen infection and potential in modulating the epithelial barrier function.
Tue Nov 01 00:00:00 UTC 2022
miR-195-5p Regulates Tight Junctions Expression via Claudin-2 Downregulation in Ulcerative Colitis.
Biomedicines
Scalavino V,Piccinno E,Lacalamita A,Tafaro A,Armentano R,Giannelli G,Serino G
51-6100 was used in Immunocytochemistry-immunofluorescence to report that negative correlation of miR-195-5p and CLDN2 is involved in regulation of intestinal tight junctions, presnting a potential pharmacological target for new therapeutic approaches in IBD.
Sat Apr 16 00:00:00 UTC 2022
miR-195-5p Regulates Tight Junctions Expression via Claudin-2 Downregulation in Ulcerative Colitis.
Biomedicines
Scalavino V,Piccinno E,Lacalamita A,Tafaro A,Armentano R,Giannelli G,Serino G
51-6100 was used in Immunocytochemistry-immunofluorescence to report that negative correlation of miR-195-5p and CLDN2 is involved in regulation of intestinal tight junctions, presnting a potential pharmacological target for new therapeutic approaches in IBD.
Sat Apr 16 00:00:00 UTC 2022
Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression.
American journal of physiology. Cell physiology
Koumangoye R,Penny P,Delpire E
51-6100 was used in Immunocytochemistry to investigate whether the loss of Na+-K+-2Cl- cotransporter function affects paracellular ion transport and epithelial barrier function.
Sat Oct 01 00:00:00 UTC 2022
The Increase of miR-195-5p Reduces Intestinal Permeability in Ulcerative Colitis, Modulating Tight Junctions' Expression.
International journal of molecular sciences
Scalavino V,Piccinno E,Bianco G,Schena N,Armentano R,Giannelli G,Serino G
51-6100 was used in ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot to investigate the modulation of miR-195-5p on the expression of CLDN2 and other TJs under inflammatory conditions induced by TNF-α.
Mon May 23 00:00:00 UTC 2022
MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier.
Cells
Weiß F,Czichos C,Knobe L,Voges L,Bojarski C,Michel G,Fromm M,Krug SM
51-6100 was used in Western Blotting to conclude that the protective effects are hardly targeting the intestinal barrier directly but are based on regulatory processes supporting stabilization of the intestinal barrier.
Wed May 04 00:00:00 UTC 2022
Nanoscale segregation of channel and barrier claudins enables paracellular ion flux.
Nature communications
Gonschior H,Schmied C,Van der Veen RE,Eichhorst J,Himmerkus N,Piontek J,Günzel D,Bleich M,Furuse M,Haucke V,Lehmann M
51-6100 was used in Immunohistochemistry to suggest that nanoscale segregation of distinct channel-forming claudins enables barrier function combined with specific paracellular ion flux across tight junctions.
Thu Aug 25 00:00:00 UTC 2022
Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis.
Proceedings of the National Academy of Sciences of the United States of America
Beggs MR,Young K,Pan W,O'Neill DD,Saurette M,Plain A,Rievaj J,Doschak MR,Cordat E,Dimke H,Alexander RT
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunohistochemistry
Tue Nov 30 00:00:00 UTC 2021
Claudin-2 and claudin-12 form independent, complementary pores required to maintain calcium homeostasis.
Proceedings of the National Academy of Sciences of the United States of America
Beggs MR,Young K,Pan W,O'Neill DD,Saurette M,Plain A,Rievaj J,Doschak MR,Cordat E,Dimke H,Alexander RT
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunohistochemistry
Tue Nov 30 00:00:00 UTC 2021
Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.
Current biology : CB
Hachimi M,Grabowski C,Campanario S,Herranz G,Baonza G,Serrador JM,Gomez-Lopez S,Barea MD,Bosch-Fortea M,Gilmour D,Bagnat M,Rodriguez-Fraticelli AE,Martin-Belmonte F
51-6100 was used in Immunocytochemistry to demonstrate the role of Smoothelin-like 2 in apical cortex maturation during epithelial morphogenesis.
Mon Feb 22 00:00:00 UTC 2021
Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis.
Current biology : CB
Hachimi M,Grabowski C,Campanario S,Herranz G,Baonza G,Serrador JM,Gomez-Lopez S,Barea MD,Bosch-Fortea M,Gilmour D,Bagnat M,Rodriguez-Fraticelli AE,Martin-Belmonte F
51-6100 was used in Immunocytochemistry to demonstrate the role of Smoothelin-like 2 in apical cortex maturation during epithelial morphogenesis.
Mon Feb 22 00:00:00 UTC 2021
Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.
Acta physiologica (Oxford, England)
Muntjewerff EM,Tang K,Lutter L,Christoffersson G,Nicolasen MJT,Gao H,Katkar GD,Das S,Ter Beest M,Ying W,Ghosh P,El Aidy S,Oldenburg B,van den Bogaart G,Mahata SK
51-6100 was used in Western Blotting to show how pro-hormone Chromogranin A, produced by the enteroendocrine cells, and Catestatin, the most abundant CgA-derived proteolytic peptide, affect the gut barrier.
Tue Jun 01 00:00:00 UTC 2021
Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides.
Acta physiologica (Oxford, England)
Muntjewerff EM,Tang K,Lutter L,Christoffersson G,Nicolasen MJT,Gao H,Katkar GD,Das S,Ter Beest M,Ying W,Ghosh P,El Aidy S,Oldenburg B,van den Bogaart G,Mahata SK
51-6100 was used in Western Blotting to show how pro-hormone Chromogranin A, produced by the enteroendocrine cells, and Catestatin, the most abundant CgA-derived proteolytic peptide, affect the gut barrier.
Tue Jun 01 00:00:00 UTC 2021
Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.
Cells
Reyes Nicolás V,Allaire JM,Alfonso AB,Pupo Gómez D,Pomerleau V,Giroux V,Boudreau F,Perreault N
51-6100 was used in Immunohistochemistry to investigate how the loss of BMP signalling in TCFoxL1+ influences the severity of inflammation and fosters epithelial recovery after inflammatory stress.
Fri Oct 29 00:00:00 UTC 2021
Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling.
Cells
Reyes Nicolás V,Allaire JM,Alfonso AB,Pupo Gómez D,Pomerleau V,Giroux V,Boudreau F,Perreault N
51-6100 was used in Immunohistochemistry to investigate how the loss of BMP signalling in TCFoxL1+ influences the severity of inflammation and fosters epithelial recovery after inflammatory stress.
Fri Oct 29 00:00:00 UTC 2021
Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells.
International journal of molecular sciences
Eguchi H,Matsunaga H,Onuma S,Yoshino Y,Matsunaga T,Ikari A
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Wed Jan 06 00:00:00 UTC 2021
Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells.
International journal of molecular sciences
Eguchi H,Matsunaga H,Onuma S,Yoshino Y,Matsunaga T,Ikari A
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Wed Jan 06 00:00:00 UTC 2021
Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal.
International journal of molecular sciences
Ito A,Nasako H,Akizuki R,Takashina Y,Eguchi H,Matsunaga T,Yoshino Y,Endo S,Ikari A
51-6100 was used in Immunocytochemistry to clarify the mechanism by which claudin-2 (CLDN2), a tight junctional protein, is involved in the chemoresistance in a three-dimensional spheroid culture model of human lung adenocarcinoma A549 cells.
Sat Jun 19 00:00:00 UTC 2021
Elevation of Chemosensitivity of Lung Adenocarcinoma A549 Spheroid Cells by Claudin-2 Knockdown through Activation of Glucose Transport and Inhibition of Nrf2 Signal.
International journal of molecular sciences
Ito A,Nasako H,Akizuki R,Takashina Y,Eguchi H,Matsunaga T,Yoshino Y,Endo S,Ikari A
51-6100 was used in Immunocytochemistry to clarify the mechanism by which claudin-2 (CLDN2), a tight junctional protein, is involved in the chemoresistance in a three-dimensional spheroid culture model of human lung adenocarcinoma A549 cells.
Sat Jun 19 00:00:00 UTC 2021
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice.
The Journal of clinical investigation
Raju P,Shashikanth N,Tsai PY,Pongkorpsakol P,Chanez-Paredes S,Steinhagen PR,Kuo WT,Singh G,Tsukita S,Turner JR
51-6100 was used in an ELISA assay to define the impact of claudin-2 channels on disease using mice models.
Thu Oct 01 00:00:00 UTC 2020
E7 oncoprotein from human papillomavirus 16 alters claudins expression and the sealing of epithelial tight junctions.
International journal of oncology
Uc PY,Miranda J,Raya-Sandino A,Alarcón L,Roldán ML,Ocadiz-Delgado R,Cortés-Malagón EM,Chávez-Munguía B,Ramírez G,Asomoza R,Shoshani L,Gariglio P,González-Mariscal L
51-6100 was used in Western Blotting to investigate the role of human papillomavirus (HPV) 16 E7 oncoprotein on the sealing of TJs, and also the expression level of claudins in mouse cervix and in epithelial Madin‚Darby Canine Kidney (MDCK) cells.
Thu Oct 01 00:00:00 UTC 2020
Expression of Tight Junction Proteins According to Functional Dyspepsia Subtype and Sex.
Journal of neurogastroenterology and motility
Lee JY,Kim N,Choi YJ,Park JH,Ashktorab H,Smoot DT,Lee DH
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Thu Apr 30 00:00:00 UTC 2020
Expression of Tight Junction Proteins According to Functional Dyspepsia Subtype and Sex.
Journal of neurogastroenterology and motility
Lee JY,Kim N,Choi YJ,Park JH,Ashktorab H,Smoot DT,Lee DH
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Thu Apr 30 00:00:00 UTC 2020
A Low Cost Antibody Signal Enhancer Improves Immunolabeling in Cell Culture, Primate Brain and Human Cancer Biopsy.
Neuroscience
Flores-Maldonado C,Albino-Sánchez ME,Rodríguez-Callejas JD,Estrada-Mondragon A,León-Galicia I,Maqueda-Alfaro R,Perez-Cruz C,Fuchs E,García-Carrancá A,Contreras RG,Missirlis F,Rosas-Arellano A
51-6100 was used in Immunocytochemistry to describe three new settings in which ASE improves the detection of a variety of antibodies applied on long-time stored non-human primate brain sections, cell culture monolayers and on squamous carcinomas retrieved from cervical cancer patients.
Wed Jul 15 00:00:00 UTC 2020
Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton.
Experimental and therapeutic medicine
Wang H,Jiang Y,Li H,Wang J,Li C,Zhang D
51-6100 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that carbachol may protect the intestinal barrier in the severe acute pancreatitis rat model without aggravating pancreatic injury via regulation of Cdc42/F-actin expression.
Tue Sep 01 00:00:00 UTC 2020
Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton.
Experimental and therapeutic medicine
Wang H,Jiang Y,Li H,Wang J,Li C,Zhang D
51-6100 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that carbachol may protect the intestinal barrier in the severe acute pancreatitis rat model without aggravating pancreatic injury via regulation of Cdc42/F-actin expression.
Tue Sep 01 00:00:00 UTC 2020
Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton.
Experimental and therapeutic medicine
Wang H,Jiang Y,Li H,Wang J,Li C,Zhang D
51-6100 was used in Western Blot, Immunohistochemistry (Paraffin) to demonstrate that carbachol may protect the intestinal barrier in the severe acute pancreatitis rat model without aggravating pancreatic injury via regulation of Cdc42/F-actin expression.
Tue Sep 01 00:00:00 UTC 2020
Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers.
Scientific reports
Cray P,Sheahan BJ,Cortes JE,Dekaney CM
51-6100 was used in Immunohistochemistry-immunofluorescence to conclude that doxorubicin increases paracellular transit of macromolecules through intestinal epithelium.
Tue Dec 08 00:00:00 UTC 2020
Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers.
Scientific reports
Cray P,Sheahan BJ,Cortes JE,Dekaney CM
51-6100 was used in Immunohistochemistry-immunofluorescence to conclude that doxorubicin increases paracellular transit of macromolecules through intestinal epithelium.
Tue Dec 08 00:00:00 UTC 2020
Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
International journal of molecular sciences
Kjærgaard S,Damm MMB,Chang J,Riis LB,Rasmussen HB,Hytting-Andreasen R,Krug SM,Schulzke JD,Bindslev N,Hansen MB
51-6100 was used in Western Blot to study mucosal healing on a molecular and functional level in quiescent ulcerative colitis (UC).
Tue Mar 10 00:00:00 UTC 2020
Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
International journal of molecular sciences
Kjærgaard S,Damm MMB,Chang J,Riis LB,Rasmussen HB,Hytting-Andreasen R,Krug SM,Schulzke JD,Bindslev N,Hansen MB
51-6100 was used in Western Blot to study mucosal healing on a molecular and functional level in quiescent ulcerative colitis (UC).
Tue Mar 10 00:00:00 UTC 2020
Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
International journal of molecular sciences
Kjærgaard S,Damm MMB,Chang J,Riis LB,Rasmussen HB,Hytting-Andreasen R,Krug SM,Schulzke JD,Bindslev N,Hansen MB
51-6100 was used in Western Blot to study mucosal healing on a molecular and functional level in quiescent ulcerative colitis (UC).
Tue Mar 10 00:00:00 UTC 2020
Glycocholic acid and butyrate synergistically increase vitamin D-induced calcium uptake in Caco-2 intestinal epithelial cell monolayers.
Bone reports
Casselbrant A,Fändriks L,Wallenius V
51-6100 was used in Western Blotting to identify mechanisms in vitro that may be responsible for the decreased calcium absorption after Roux-en-Y gastric bypass.
Tue Dec 01 00:00:00 UTC 2020
Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection.
Veterinary research
Luo Y,Xu J,Zhang C,Jiang C,Ma Y,He H,Wu Y,Devriendt B,Cox E,Zhang H
51-6100 was used in Western Blotting to study the role of IL-17A during an enterotoxigenic escheria coli infection.
Thu Jun 20 00:00:00 UTC 2019
Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells.
International journal of molecular sciences
Gamero-Estevez E,Andonian S,Jean-Claude B,Gupta I,Ryan AK
51-6100 was used in Western Blotting to investigate the effect of quercetin on claudin expression and localisation in MDCK II cells, a cation-selective cell line, derived from the proximal tubule.
Wed Oct 02 00:00:00 UTC 2019
Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells.
International journal of molecular sciences
Gamero-Estevez E,Andonian S,Jean-Claude B,Gupta I,Ryan AK
51-6100 was used in Western Blotting to investigate the effect of quercetin on claudin expression and localisation in MDCK II cells, a cation-selective cell line, derived from the proximal tubule.
Wed Oct 02 00:00:00 UTC 2019
TLR3 deficiency exacerbates the loss of epithelial barrier function during genital tract Chlamydia muridarum infection.
PloS one
Kumar R,Gong H,Liu L,Ramos-Solis N,Seye CI,Derbigny WA
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Wed Sep 18 00:00:00 UTC 2019
Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability.
Cells
Miranda J,Martín-Tapia D,Valdespino-Vázquez Y,Alarcón L,Espejel-Nuñez A,Guzmán-Huerta M,Muñoz-Medina JE,Shibayama M,Chávez-Munguía B,Estrada-Gutiérrez G,Lievano S,Ludert JE,González-Mariscal L
51-6100 was used in Western Blotting to determine whether ZIKV can open the paracellular pathway of STB cells which have been seen to be resistant to ZIKV infections.
Sun Sep 29 00:00:00 UTC 2019
Apical Membrane Alterations in Non-intestinal Organs in Microvillus Inclusion Disease.
Digestive diseases and sciences
Schlegel C,Weis VG,Knowles BC,Lapierre LA,Martin MG,Dickman P,Goldenring JR,Shub MD
51-6100 was used in Immunohistochemistry-immunofluorescence to show that the effects of the P660L mutation in the MYO5B gene in Navajo Microvillus Inclusion Disease patients are not limited to the small intestine - certain tissues can compensate functionally for alterations in apical trafficking.
Thu Feb 01 00:00:00 UTC 2018
The role of human fibronectin- or placenta basement membrane extract-based gels in favouring the formation of polarized salivary acinar-like structures.
Journal of tissue engineering and regenerative medicine
Maria OM,Liu Y,El-Hakim M,Zeitouni A,Tran SD
51-6100 was used in immunocytochemistry and western blot to study the favored formation of polarized salivary acinar-like structures by the role of human fibronectin- or placenta basement membrane extract-based gels
Fri Sep 01 00:00:00 UTC 2017
Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin.
Experimental cell research
Nighot PK,Leung L,Ma TY
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunocytochemistry
Wed Mar 01 00:00:00 UTC 2017
Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin.
Experimental cell research
Nighot PK,Leung L,Ma TY
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunocytochemistry
Wed Mar 01 00:00:00 UTC 2017
Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells.
Experimental cell research
Torres-Martínez AC,Gallardo-Vera JF,Lara-Holguin AN,Montaño LF,Rendón-Huerta EP
51-6100 was used in flow cytometry to ascertain how claudin-6 is associated with MMP-2 activation and cell invasiveness
Sun Jan 01 00:00:00 UTC 2017
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.
The Journal of biological chemistry
Buzza MS,Johnson TA,Conway GD,Martin EW,Mukhopadhyay S,Shea-Donohue T,Antalis TM
51-6100 was used in Western Blotting to show that mRNA and protein expression of both matriptase and prostasin are rapidly down-regulated in the initiating inflammatory phases of dextran sulfate sodium (DSS)-induced experimental colitis in mice, and, significantly, the loss of these proteases precedes the appearance of clinical symptoms.
Fri Jun 30 00:00:00 UTC 2017
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.
The Journal of biological chemistry
Buzza MS,Johnson TA,Conway GD,Martin EW,Mukhopadhyay S,Shea-Donohue T,Antalis TM
51-6100 was used in Western Blotting to show that mRNA and protein expression of both matriptase and prostasin are rapidly down-regulated in the initiating inflammatory phases of dextran sulfate sodium (DSS)-induced experimental colitis in mice, and, significantly, the loss of these proteases precedes the appearance of clinical symptoms.
Fri Jun 30 00:00:00 UTC 2017
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.
Molecular vision
Samuel W,Jaworski C,Postnikova OA,Kutty RK,Duncan T,Tan LX,Poliakov E,Lakkaraju A,Redmond TM
516100 was used in immunocytochemistry to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells
Fri Feb 09 00:00:00 UTC 2018
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.
Molecular vision
Samuel W,Jaworski C,Postnikova OA,Kutty RK,Duncan T,Tan LX,Poliakov E,Lakkaraju A,Redmond TM
516100 was used in immunocytochemistry to identify conditions in which low-passage ARPE-19 cells express genes specific to native human RPE cells
Fri Feb 09 00:00:00 UTC 2018
Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers.
International journal of molecular sciences
Zhang C,Yan J,Xiao Y,Shen Y,Wang J,Ge W,Chen Y
51-6100 was used in immunocytochemistry and western blot to assess the effect of TNF-alpha on claudin-2 expression and tight junction function
Tue Jan 17 00:00:00 UTC 2017
Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers.
International journal of molecular sciences
Zhang C,Yan J,Xiao Y,Shen Y,Wang J,Ge W,Chen Y
51-6100 was used in immunocytochemistry and western blot to assess the effect of TNF-alpha on claudin-2 expression and tight junction function
Tue Jan 17 00:00:00 UTC 2017
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
The Journal of biological chemistry
Hichino A,Okamoto M,Taga S,Akizuki R,Endo S,Matsunaga T,Ikari A
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Western Blot
Fri Feb 10 00:00:00 UTC 2017
The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction.
American journal of physiology. Gastrointestinal and liver physiology
Ronaghan NJ,Shang J,Iablokov V,Zaheer R,Colarusso P,Dion S,Désilets A,Leduc R,Turner JR,MacNaughton WK
516100 was used in western blot to investigate how serine proteases increase transepithelial electrical resistance
Thu Sep 01 00:00:00 UTC 2016
Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues.
Journal of veterinary science
Lee B,Kang HY,Lee DO,Ahn C,Jeung EB
51-6100 was used in immunohistochemistry - paraffin section and western blot to compare expression levels and distribution of Claudin-1, 2, 4, and 5 in equine tissues
Fri Dec 30 00:00:00 UTC 2016
Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues.
Journal of veterinary science
Lee B,Kang HY,Lee DO,Ahn C,Jeung EB
51-6100 was used in immunohistochemistry - paraffin section and western blot to compare expression levels and distribution of Claudin-1, 2, 4, and 5 in equine tissues
Fri Dec 30 00:00:00 UTC 2016
Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
Scientific reports
Lepage D,Bélanger É,Jones C,Tremblay S,Allaire JM,Bruneau J,Asselin C,Perreault N,Menendez A,Gendron FP,Boudreau F
516100 was used in western blot to show that Gata4 regulates barrier integrity in the mouse proximal intestinal epithelium
Wed Nov 09 00:00:00 UTC 2016
Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
Scientific reports
Lepage D,Bélanger É,Jones C,Tremblay S,Allaire JM,Bruneau J,Asselin C,Perreault N,Menendez A,Gendron FP,Boudreau F
516100 was used in western blot to show that Gata4 regulates barrier integrity in the mouse proximal intestinal epithelium
Wed Nov 09 00:00:00 UTC 2016
Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.
mBio
Phillips SL,Soderblom EJ,Bradrick SS,Garcia-Blanco MA
51-6100 was used in western blot to describe a method to identify host RNA-binding proteins during Dengue virus infection
Tue Jan 05 00:00:00 UTC 2016
Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.
mBio
Phillips SL,Soderblom EJ,Bradrick SS,Garcia-Blanco MA
51-6100 was used in western blot to describe a method to identify host RNA-binding proteins during Dengue virus infection
Tue Jan 05 00:00:00 UTC 2016
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.
The Journal of biological chemistry
Fujii N,Matsuo Y,Matsunaga T,Endo S,Sakai H,Yamaguchi M,Yamazaki Y,Sugatani J,Ikari A
516100 was used in immunocytochemistry and western blot to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells
Fri Nov 18 00:00:00 UTC 2016
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.
The Journal of biological chemistry
Fujii N,Matsuo Y,Matsunaga T,Endo S,Sakai H,Yamaguchi M,Yamazaki Y,Sugatani J,Ikari A
516100 was used in immunocytochemistry and western blot to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells
Fri Nov 18 00:00:00 UTC 2016
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.
The Journal of biological chemistry
Fujii N,Matsuo Y,Matsunaga T,Endo S,Sakai H,Yamaguchi M,Yamazaki Y,Sugatani J,Ikari A
516100 was used in immunocytochemistry and western blot to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells
Fri Nov 18 00:00:00 UTC 2016
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.
The Journal of biological chemistry
Fujii N,Matsuo Y,Matsunaga T,Endo S,Sakai H,Yamaguchi M,Yamazaki Y,Sugatani J,Ikari A
516100 was used in immunocytochemistry and western blot to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells
Fri Nov 18 00:00:00 UTC 2016
Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.
The Journal of biological chemistry
Fujii N,Matsuo Y,Matsunaga T,Endo S,Sakai H,Yamaguchi M,Yamazaki Y,Sugatani J,Ikari A
516100 was used in immunocytochemistry and western blot to elucidate the mechanism by which hypotonic stress reduces claudin-1 and -2 expression in renal tubular epithelial and canine kidney cells
Fri Nov 18 00:00:00 UTC 2016
Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.
PloS one
Randall K,Henderson N,Reens J,Eckersley S,Nyström AC,South MC,Balendran CA,Böttcher G,Hughes G,Price SA
51-6100 was used in Immunocytochemistry to demonstrate that increased claudin-2 expression correlates with the severity of ulcerative colitis, where crypt destruction is not seen.
Wed Aug 02 00:00:00 UTC 2017
Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier.
Fluids and barriers of the CNS
Lazarevic I,Engelhardt B
51-6100 was used in immunocytochemistry to study a model of immune functions of the mouse blood-cerebrospinal fluid barrier in vitro using primary epithelial cells better suited to study immune cell migration across the brain barrier
Fri Jan 29 00:00:00 UTC 2016
T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium.
PloS one
Strazielle N,Creidy R,Malcus C,Boucraut J,Ghersi-Egea JF
51-6100 was used in immunocytochemistry to study a reconstituted choroid plexus epithelium to show T-lymphocytes traffic into the brain across the blood-CSF barrier
Mon Jul 25 00:00:00 UTC 2016
Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers.
Biomaterials
Staat C,Coisne C,Dabrowski S,Stamatovic SM,Andjelkovic AV,Wolburg H,Engelhardt B,Blasig IE
51-6100 was used in immunocytochemistry to investigate the role of claudin-1/claudin-5 in epithelial/endothelial barriers
Mon Jun 01 00:00:00 UTC 2015
EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells.
Journal of cellular physiology
García-Hernández V,Flores-Maldonado C,Rincon-Heredia R,Verdejo-Torres O,Bonilla-Delgado J,Meneses-Morales I,Gariglio P,Contreras RG
51-6100 was used in immunocytochemistry and western blot to investigate the effect of EGF on claudin-2 and -4 expression in MDCK cells.
Thu Jan 01 00:00:00 UTC 2015
Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions.
American journal of physiology. Cell physiology
Amoozadeh Y,Dan Q,Xiao J,Waheed F,Szászi K
51-6100 was used in immunocytochemistry and western blot to study the effects of TNF exposure on tight junction proteins using LLC-PK1 tubular cells.
Wed Jul 01 00:00:00 UTC 2015
Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions.
American journal of physiology. Cell physiology
Amoozadeh Y,Dan Q,Xiao J,Waheed F,Szászi K
51-6100 was used in immunocytochemistry and western blot to study the effects of TNF exposure on tight junction proteins using LLC-PK1 tubular cells.
Wed Jul 01 00:00:00 UTC 2015
Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions.
American journal of physiology. Cell physiology
Amoozadeh Y,Dan Q,Xiao J,Waheed F,Szászi K
51-6100 was used in immunocytochemistry and western blot to study the effects of TNF exposure on tight junction proteins using LLC-PK1 tubular cells.
Wed Jul 01 00:00:00 UTC 2015
Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Casselbrant A,Elias E,Fändriks L,Wallenius V
51-6100 was used in western blot to study tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery
Fri Jan 15 00:00:00 UTC 2016
Alterations of intercellular junctions in peritoneal mesothelial cells from patients undergoing dialysis: effect of retinoic Acid.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Retana C,Sanchez E,Perez-Lopez A,Cruz A,Lagunas J,Cruz C,Vital S,Reyes JL
51-6100 was used in immunocytochemistry and western blot to determine the quantity, distribution and function of tight junction proteins in patients undergoing dialysis treatments
Tue Apr 05 00:00:00 UTC 2016
Alterations of intercellular junctions in peritoneal mesothelial cells from patients undergoing dialysis: effect of retinoic Acid.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Retana C,Sanchez E,Perez-Lopez A,Cruz A,Lagunas J,Cruz C,Vital S,Reyes JL
51-6100 was used in immunocytochemistry and western blot to determine the quantity, distribution and function of tight junction proteins in patients undergoing dialysis treatments
Tue Apr 05 00:00:00 UTC 2016
Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells.
PloS one
Maggiorani D,Dissard R,Belloy M,Saulnier-Blache JS,Casemayou A,Ducasse L,Grès S,Bellière J,Caubet C,Bascands JL,Schanstra JP,Buffin-Meyer B
51-6100 was used in immunocytochemistry to test if urinary fluid shear stress alters the epithelial characteristics of the renal tubule.
Wed Apr 06 00:00:00 UTC 2016
Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells.
PloS one
Maggiorani D,Dissard R,Belloy M,Saulnier-Blache JS,Casemayou A,Ducasse L,Grès S,Bellière J,Caubet C,Bascands JL,Schanstra JP,Buffin-Meyer B
51-6100 was used in immunocytochemistry to test if urinary fluid shear stress alters the epithelial characteristics of the renal tubule.
Wed Apr 06 00:00:00 UTC 2016
A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment.
Molecular cancer
Lu Z,Kim DH,Fan J,Lu Q,Verbanac K,Ding L,Renegar R,Chen YH
51-6100 was used in Western Blot to investigate the functional significance of non-tight junction localisation of claudin-7 in human lung cancer cells.
Wed Jun 17 00:00:00 UTC 2015
Ouabain induces endocytosis and degradation of tight junction proteins through ERK1/2-dependent pathways.
Experimental cell research
Rincon-Heredia R,Flores-Benitez D,Flores-Maldonado C,Bonilla-Delgado J,García-Hernández V,Verdejo-Torres O,Castillo AM,Larré I,Poot-Hernández AC,Franco M,Gariglio P,Reyes JL,Contreras RG
51-6100 was used in immunocytochemistry and western blot to investigate the effect of ouabain on endocytosis and degradation of tight junction proteins
Wed Jan 01 00:00:00 UTC 2014
Diets high in fermentable protein and fibre alter tight junction protein composition with minor effects on barrier function in piglet colon.
The British journal of nutrition
Richter JF,Pieper R,Zakrzewski SS,Günzel D,Schulzke JD,Van Kessel AG
51-6100 was used in western blot to study the effects on piglet colon tight junction composition of a diet high in fibre and fermentable proteins.
Fri Mar 28 00:00:00 UTC 2014
Impaired intestinal mucosal barrier upon ischemia-reperfusion: "patching holes in the shield with a simple surgical method".
BioMed research international
Rosero O,Ónody P,Kovács T,Molnár D,Lotz G,Tóth S,Turóczi Z,Fülöp A,Garbaisz D,Harsányi L,Szijártó A
51-6100 was used in immunohistochemistry - paraffin section to study the effect of ischemia-reperfusion on intestinal mucosal barrier
Thu Feb 12 00:00:00 UTC 2015
Impaired intestinal mucosal barrier upon ischemia-reperfusion: "patching holes in the shield with a simple surgical method".
BioMed research international
Rosero O,Ónody P,Kovács T,Molnár D,Lotz G,Tóth S,Turóczi Z,Fülöp A,Garbaisz D,Harsányi L,Szijártó A
51-6100 was used in immunohistochemistry - paraffin section to study the effect of ischemia-reperfusion on intestinal mucosal barrier
Thu Feb 12 00:00:00 UTC 2015
Loss of EP2 receptor subtype in colonic cells compromise epithelial barrier integrity by altering claudin-4.
PloS one
Lejeune M,Moreau F,Chadee K
51-6100 was used in western blot to investigate the role of EP2 receptor subtype in colonic epithelial barrier.
Mon Dec 21 00:00:00 UTC 2015
Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease.
PloS one
Rossi G,Pengo G,Caldin M,Palumbo Piccionello A,Steiner JM,Cohen ND,Jergens AE,Suchodolski JS
51-6100 was used in immunohistochemistry to compare two treatment regiments for idiopathic inflammatory bowel disease
Fri Jun 05 00:00:00 UTC 2015
Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions.
Cell host & microbe
Guichard A,Cruz-Moreno B,Aguilar B,van Sorge NM,Kuang J,Kurkciyan AA,Wang Z,Hang S,Pineton de Chambrun GP,McCole DF,Watnick P,Nizet V,Bier E
51-6100 was used in immunocytochemistry to study how Rab inhibits the barrier-disrupting effects of CtxA.
Wed Sep 11 00:00:00 UTC 2013
H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.
Cellular immunology
Song X,Chen HX,Wang XY,Deng XY,Xi YX,He Q,Peng TL,Chen J,Chen W,Wong BC,Chen MH
51-6100 was used in western blot to show that H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.
Wed Feb 05 00:00:00 UTC 2014
Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.
BMC gastroenterology
Mann EA,Harmel-Laws E,Cohen MB,Steinbrecher KA
51-6100 was used in immunohistochemistry (frozen) to test if GC-C is required for host defense during Citrobacter rodentium infection.
Mon Sep 02 00:00:00 UTC 2013
Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.
BMC gastroenterology
Mann EA,Harmel-Laws E,Cohen MB,Steinbrecher KA
51-6100 was used in immunohistochemistry (frozen) to test if GC-C is required for host defense during Citrobacter rodentium infection.
Mon Sep 02 00:00:00 UTC 2013
Transmigration of neural stem cells across the blood brain barrier induced by glioma cells.
PloS one
Díaz-Coránguez M,Segovia J,López-Ornelas A,Puerta-Guardo H,Ludert J,Chávez B,Meraz-Cruz N,González-Mariscal L
51-6100 was used in western blot to evaluate an in vitro model of blood brain barrier
Tue Nov 26 00:00:00 UTC 2013
Transmigration of neural stem cells across the blood brain barrier induced by glioma cells.
PloS one
Díaz-Coránguez M,Segovia J,López-Ornelas A,Puerta-Guardo H,Ludert J,Chávez B,Meraz-Cruz N,González-Mariscal L
51-6100 was used in western blot to evaluate an in vitro model of blood brain barrier
Tue Nov 26 00:00:00 UTC 2013
Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes.
Molecular and cellular biology
Tabariès S,Dupuy F,Dong Z,Monast A,Annis MG,Spicer J,Ferri LE,Omeroglu A,Basik M,Amir E,Clemons M,Siegel PM
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunoprecipitation
Wed Aug 01 00:00:00 UTC 2012
Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes.
Molecular and cellular biology
Tabariès S,Dupuy F,Dong Z,Monast A,Annis MG,Spicer J,Ferri LE,Omeroglu A,Basik M,Amir E,Clemons M,Siegel PM
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunoprecipitation
Wed Aug 01 00:00:00 UTC 2012
Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes.
Molecular and cellular biology
Tabariès S,Dupuy F,Dong Z,Monast A,Annis MG,Spicer J,Ferri LE,Omeroglu A,Basik M,Amir E,Clemons M,Siegel PM
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunoprecipitation
Wed Aug 01 00:00:00 UTC 2012
Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes.
Molecular and cellular biology
Tabariès S,Dupuy F,Dong Z,Monast A,Annis MG,Spicer J,Ferri LE,Omeroglu A,Basik M,Amir E,Clemons M,Siegel PM
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunoprecipitation
Wed Aug 01 00:00:00 UTC 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 UTC 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 UTC 2012
Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells.
Molecular biology of the cell
Lapierre LA,Avant KM,Caldwell CM,Oztan A,Apodaca G,Knowles BC,Roland JT,Ducharme NA,Goldenring JR
Published figure using Claudin 2 polyclonal antibody (Product # 51-6100) in Immunofluorescence
Fri Jun 01 00:00:00 UTC 2012
Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon.
American journal of physiology. Regulatory, integrative and comparative physiology
Engelund MB,Yu AS,Li J,Madsen SS,Færgeman NJ,Tipsmark CK
Sun Jan 15 00:00:00 UTC 2012
Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon.
American journal of physiology. Regulatory, integrative and comparative physiology
Engelund MB,Yu AS,Li J,Madsen SS,Færgeman NJ,Tipsmark CK
Sun Jan 15 00:00:00 UTC 2012
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.
Histochemistry and cell biology
Kratzer I,Vasiljevic A,Rey C,Fevre-Montange M,Saunders N,Strazielle N,Ghersi-Egea JF
Sat Dec 01 00:00:00 UTC 2012
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.
Histochemistry and cell biology
Kratzer I,Vasiljevic A,Rey C,Fevre-Montange M,Saunders N,Strazielle N,Ghersi-Egea JF
Sat Dec 01 00:00:00 UTC 2012
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.
Histochemistry and cell biology
Kratzer I,Vasiljevic A,Rey C,Fevre-Montange M,Saunders N,Strazielle N,Ghersi-Egea JF
Sat Dec 01 00:00:00 UTC 2012
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.
Histochemistry and cell biology
Kratzer I,Vasiljevic A,Rey C,Fevre-Montange M,Saunders N,Strazielle N,Ghersi-Egea JF
Sat Dec 01 00:00:00 UTC 2012
A novel microfluidics-based method for probing weak protein-protein interactions.
Lab on a chip
Tan DC,Wijaya IP,Andreasson-Ochsner M,Vasina EN,Nallani M,Hunziker W,Sinner EK
51-6100 was used in western blot to develop a novel microfluidics-based method to detect weak protein-protein interactions between membrane proteins.
Tue Aug 07 00:00:00 UTC 2012
Role of tight junction proteins in gastroesophageal reflux disease.
BMC gastroenterology
Mönkemüller K,Wex T,Kuester D,Fry LC,Kandulski A,Kropf S,Roessner A,Malfertheiner P
51-6100 was used in immunohistochemistry to determine the expression pattern of selected components involved in the formation of tight junctions in relation to gastroesophageal reflux disease
Thu Sep 20 00:00:00 UTC 2012
Ouabain modulates ciliogenesis in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America
Larre I,Castillo A,Flores-Maldonado C,Contreras RG,Galvan I,Muñoz-Estrada J,Cereijido M
51-6100 was used in immunocytochemistry and western blot to investigate the effect of ouabain on cilia development in epithelial cells
Tue Dec 20 00:00:00 UTC 2011
Ouabain modulates ciliogenesis in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America
Larre I,Castillo A,Flores-Maldonado C,Contreras RG,Galvan I,Muñoz-Estrada J,Cereijido M
51-6100 was used in immunocytochemistry and western blot to investigate the effect of ouabain on cilia development in epithelial cells
Tue Dec 20 00:00:00 UTC 2011
Loss of Smad5 leads to the disassembly of the apical junctional complex and increased susceptibility to experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology
Allaire JM,Darsigny M,Marcoux SS,Roy SA,Schmouth JF,Umans L,Zwijsen A,Boudreau F,Perreault N
51-6100 was used in immunohistochemistry and western blot to characterize mice in which Smad5 is deleted exclusively in the intestinal epithelium.
Fri Apr 01 00:00:00 UTC 2011
Loss of Smad5 leads to the disassembly of the apical junctional complex and increased susceptibility to experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology
Allaire JM,Darsigny M,Marcoux SS,Roy SA,Schmouth JF,Umans L,Zwijsen A,Boudreau F,Perreault N
51-6100 was used in immunohistochemistry and western blot to characterize mice in which Smad5 is deleted exclusively in the intestinal epithelium.
Fri Apr 01 00:00:00 UTC 2011
Matrigel improves functional properties of primary human salivary gland cells.
Tissue engineering. Part A
Maria OM,Zeitouni A,Gologan O,Tran SD
51-6100 was used in immunohistochemistry to characterize a graft source from human salivary glands.
Sun May 01 00:00:00 UTC 2011
Identification of claudins by western blot and immunofluorescence in different cell lines and tissues.
Methods in molecular biology (Clifton, N.J.)
González-Mariscal L,Garay E,Quirós M
51-6100 was used in Western Blot to describe in detail protocols used for western blot and immunofluorescence detection of claudins in epithelial cell lines and in various tissue samples.
Fri Nov 04 00:00:00 UTC 2011
Dynamics of claudins expression in colitis and colitis-associated cancer in rat.
Methods in molecular biology (Clifton, N.J.)
Arimura Y,Nagaishi K,Hosokawa M
Fri Nov 04 00:00:00 UTC 2011
Dynamics of claudins expression in colitis and colitis-associated cancer in rat.
Methods in molecular biology (Clifton, N.J.)
Arimura Y,Nagaishi K,Hosokawa M
Fri Nov 04 00:00:00 UTC 2011
Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells.
Gastroenterology
Chang TL,Ito K,Ko TK,Liu Q,Salto-Tellez M,Yeoh KG,Fukamachi H,Ito Y
51-6100 was used in Western Blotting to identify RUNX3 target genes that promote cell-cell contact in gastric epithelial cells.
Fri Jan 01 00:00:00 UTC 2010
Ovarian hormones control the changing expression of claudins and occludin in rat uterine epithelial cells during early pregnancy.
Acta histochemica
Nicholson MD,Lindsay LA,Murphy CR
51-6100 was used in immunohistochemistry - frozen section and western blot to examine the cellular distributions of tight junction components during early pregnancy and under various hormonal regimens
Thu Mar 04 00:00:00 UTC 2010
Tight junction proteins in human Schwann cell autotypic junctions.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Alanne MH,Pummi K,Heape AM,Grènman R,Peltonen J,Peltonen S
51-6100 was used in immunohistochemistry - frozen section to study the expression of adherens junction and tight junction components in human peripheral nerve endoneurium
Mon Jun 01 00:00:00 UTC 2009
Distribution of tight junction proteins in adult human salivary glands.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Maria OM,Kim JW,Gerstenhaber JA,Baum BJ,Tran SD
Mon Dec 01 00:00:00 UTC 2008
Tight and adherens junctions in the ovine uterus: differential regulation by pregnancy and progesterone.
Endocrinology
Satterfield MC,Dunlap KA,Hayashi K,Burghardt RC,Spencer TE,Bazer FW
51-6100 was used in Immunohistochemistry to identify changes in junctional complexes in the ovine endometrium that regulate paracellular trafficking of water, ions, and other molecules, and the secretory capacity of the uterine epithelia.
Wed Aug 01 00:00:00 UTC 2007
Cadmium causes delayed effects on renal function in the offspring of cadmium-contaminated pregnant female rats.
American journal of physiology. Renal physiology
Jacquillet G,Barbier O,Rubera I,Tauc M,Borderie A,Namorado MC,Martin D,Sierra G,Reyes JL,Poujeol P,Cougnon M
51-6100 was used in immunohistochemistry - frozen section to test if intoxication of pregnant rats has any deleterious effects on the offspring's renal function
Thu Nov 01 00:00:00 UTC 2007
Differences in claudin synthesis in primary cultures of acinar cells from rat salivary gland are correlated with the specific three-dimensional organization of the cells.
Cell and tissue research
Qi B,Fujita-Yoshigaki J,Michikawa H,Satoh K,Katsumata O,Sugiya H
Sun Jul 01 00:00:00 UTC 2007
Zinc protects renal function during cadmium intoxication in the rat.
American journal of physiology. Renal physiology
Jacquillet G,Barbier O,Cougnon M,Tauc M,Namorado MC,Martin D,Reyes JL,Poujeol P
Sun Jan 01 00:00:00 UTC 2006
An optimized in vitro model of the respiratory tract wall to study particle cell interactions.
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine
Blank F,Rothen-Rutishauser BM,Schurch S,Gehr P
51-6100 was used in immunocytochemistry to develop an in vitro model of the respiratory tract wall
Tue Jan 16 00:00:00 UTC 2007
A three-dimensional cellular model of the human respiratory tract to study the interaction with particles.
American journal of respiratory cell and molecular biology
Rothen-Rutishauser BM,Kiama SG,Gehr P
51-6100 was used in immunocytochemistry to develop and characterize a triple co-culture model of the human airway barrier
Fri Apr 01 00:00:00 UTC 2005
Amphiregulin causes functional downregulation of adherens junctions in psoriasis.
The Journal of investigative dermatology
Chung E,Cook PW,Parkos CA,Park YK,Pittelkow MR,Coffey RJ
Wed Jun 01 00:00:00 UTC 2005
Amphiregulin causes functional downregulation of adherens junctions in psoriasis.
The Journal of investigative dermatology
Chung E,Cook PW,Parkos CA,Park YK,Pittelkow MR,Coffey RJ
Wed Jun 01 00:00:00 UTC 2005
Impairment of blood-cerebrospinal fluid barrier properties by retrovirus-activated T lymphocytes: reduction in cerebrospinal fluid-to-blood efflux of prostaglandin E2.
Journal of neurochemistry
Khuth ST,Strazielle N,Giraudon P,Belin MF,Ghersi-Egea JF
51-6100 was used in immunocytochemistry to study the blood-CSF barrier in neuroinfectious and inflammatory diseases using a differentiated cellular model of the choroidal epithelium.
Thu Sep 01 00:00:00 UTC 2005
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.
Laboratory investigation; a journal of technical methods and pathology
Prasad S,Mingrino R,Kaukinen K,Hayes KL,Powell RM,MacDonald TT,Collins JE
Thu Sep 01 00:00:00 UTC 2005
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.
Laboratory investigation; a journal of technical methods and pathology
Prasad S,Mingrino R,Kaukinen K,Hayes KL,Powell RM,MacDonald TT,Collins JE
Thu Sep 01 00:00:00 UTC 2005
Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins.
American journal of physiology. Cell physiology
Carrozzino F,Soulié P,Huber D,Mensi N,Orci L,Cano A,Féraille E,Montesano R
Sat Oct 01 00:00:00 UTC 2005
Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins.
American journal of physiology. Cell physiology
Carrozzino F,Soulié P,Huber D,Mensi N,Orci L,Cano A,Féraille E,Montesano R
Sat Oct 01 00:00:00 UTC 2005
Cultured monolayers of the dog jejunum with the structural and functional properties resembling the normal epithelium.
American journal of physiology. Gastrointestinal and liver physiology
Weng XH,Beyenbach KW,Quaroni A
Fri Apr 01 00:00:00 UTC 2005
Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology
Guo X,Rao JN,Liu L,Zou T,Keledjian KM,Boneva D,Marasa BS,Wang JY
Wed Jun 01 00:00:00 UTC 2005
Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells.
The Journal of biological chemistry
Lipschutz JH,Li S,Arisco A,Balkovetz DF
Fri Feb 04 00:00:00 UTC 2005
Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells.
The Journal of biological chemistry
Lipschutz JH,Li S,Arisco A,Balkovetz DF
Fri Feb 04 00:00:00 UTC 2005
Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.
Proceedings of the National Academy of Sciences of the United States of America
Kahle KT,Macgregor GG,Wilson FH,Van Hoek AN,Brown D,Ardito T,Kashgarian M,Giebisch G,Hebert SC,Boulpaep EL,Lifton RP
Tue Oct 12 00:00:00 UTC 2004
Ochratoxin A increases permeability through tight junctions by removal of specific claudin isoforms.
American journal of physiology. Cell physiology
McLaughlin J,Padfield PJ,Burt JP,O'Neill CA
Mon Nov 01 00:00:00 UTC 2004
Ochratoxin A increases permeability through tight junctions by removal of specific claudin isoforms.
American journal of physiology. Cell physiology
McLaughlin J,Padfield PJ,Burt JP,O'Neill CA
Mon Nov 01 00:00:00 UTC 2004
The specific fates of tight junction proteins in apoptotic epithelial cells.
Journal of cell science
Bojarski C,Weiske J,Schöneberg T,Schröder W,Mankertz J,Schulzke JD,Florian P,Fromm M,Tauber R,Huber O
Thu Apr 15 00:00:00 UTC 2004
Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cells.
Journal of cell science
Yeaman C,Grindstaff KK,Nelson WJ
Sun Feb 01 00:00:00 UTC 2004
Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cells.
Journal of cell science
Yeaman C,Grindstaff KK,Nelson WJ
Sun Feb 01 00:00:00 UTC 2004
Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation.
American journal of physiology. Gastrointestinal and liver physiology
Barmeyer C,Harren M,Schmitz H,Heinzel-Pleines U,Mankertz J,Seidler U,Horak I,Wiedenmann B,Fromm M,Schulzke JD
Sun Feb 01 00:00:00 UTC 2004
Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Pummi KP,Heape AM,Grénman RA,Peltonen JT,Peltonen SA
51-6100 was used in immunohistochemistry to report the expression of tight junction proteins in the perineurium of adult human peripheral nerve
Sun Aug 01 00:00:00 UTC 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 UTC 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 UTC 2004
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.
American journal of physiology. Renal physiology
Acharya P,Beckel J,Ruiz WG,Wang E,Rojas R,Birder L,Apodaca G
Sun Aug 01 00:00:00 UTC 2004
Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells.
The Journal of biological chemistry
Singh AB,Harris RC
Fri Jan 30 00:00:00 UTC 2004
Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells.
The Journal of biological chemistry
Singh AB,Harris RC
Fri Jan 30 00:00:00 UTC 2004
Bryostatin-1 enhances barrier function in T84 epithelia through PKC-dependent regulation of tight junction proteins.
American journal of physiology. Cell physiology
Yoo J,Nichols A,Mammen J,Calvo I,Song JC,Worrell RT,Matlin K,Matthews JB
Fri Aug 01 00:00:00 UTC 2003
Bryostatin-1 enhances barrier function in T84 epithelia through PKC-dependent regulation of tight junction proteins.
American journal of physiology. Cell physiology
Yoo J,Nichols A,Mammen J,Calvo I,Song JC,Worrell RT,Matlin K,Matthews JB
Fri Aug 01 00:00:00 UTC 2003
Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins.
American journal of physiology. Renal physiology
Van Itallie CM,Fanning AS,Anderson JM
Mon Dec 01 00:00:00 UTC 2003
Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins.
American journal of physiology. Renal physiology
Van Itallie CM,Fanning AS,Anderson JM
Mon Dec 01 00:00:00 UTC 2003
Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation.
The Journal of biological chemistry
Yu AS,Enck AH,Lencer WI,Schneeberger EE
Fri May 09 00:00:00 UTC 2003
Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation.
The Journal of biological chemistry
Yu AS,Enck AH,Lencer WI,Schneeberger EE
Fri May 09 00:00:00 UTC 2003
Mechanisms of diarrhea in collagenous colitis.
Gastroenterology
Bürgel N,Bojarski C,Mankertz J,Zeitz M,Fromm M,Schulzke JD
Thu Aug 01 00:00:00 UTC 2002
The renal segmental distribution of claudins changes with development.
Kidney international
Reyes JL,Lamas M,Martin D,del Carmen Namorado M,Islas S,Luna J,Tauc M,González-Mariscal L
51-6100 was used in immunohistochemistry - frozen section and western blot to examine the differential expression of occludin and several claudins in isolated renal tubules from newborn and adult rabbits.
Thu Aug 01 00:00:00 UTC 2002
Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.
The Journal of cell biology
Poliak S,Matlis S,Ullmer C,Scherer SS,Peles E
Mon Oct 28 00:00:00 UTC 2002
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells.
Journal of cell science
Amasheh S,Meiri N,Gitter AH,Schöneberg T,Mankertz J,Schulzke JD,Fromm M
Sun Dec 15 00:00:00 UTC 2002
E-Cadherin and tight junctions between epithelial cells of different animal species.
Pflugers Archiv : European journal of physiology
Contreras RG,Shoshani L,Flores-Maldonado C,Lázaro A,Monroy AO,Roldán ML,Fiorentino R,Cereijido M
51-6100 was used in immunocytochemistry to investigate tight junctions and E-cadherin in heterotypic borders.
Mon Jul 01 00:00:00 UTC 2002
Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctions.
The Journal of biological chemistry
Nishiyama R,Sakaguchi T,Kinugasa T,Gu X,MacDermott RP,Podolsky DK,Reinecker HC
Fri Sep 21 00:00:00 UTC 2001
