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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Claudin 4 Antibodies

          Invitrogen

          Claudin 4 Polyclonal Antibody (ZMD.306)

          Advanced Verification
          55 Published Figures
          104 References
          View all (15) Claudin 4 antibodies

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          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite Claudin 4 Polyclonal Antibody (ZMD.306)

          • Antibody Testing Data (1)
          • Published Figures (55)
          • Advanced Verification (2)
          Claudin 4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          Claudin 4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 58

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          Claudin 4 Antibody (36-4800) in WB

          Western blot analysis of (left) mouse and (right rat kidney homogenates using Rabbit anti-Claudin-4 Polyclonal Antibody (Product # 36-4800). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)
          Claudin 4 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry (ICC/IF)
          Claudin 4 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)
          Claudin 4 Antibody in Immunohistochemistry, Immunohistochemistry (Paraffin) (IHC, IHC (P))
          Claudin 4 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Claudin 4 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Claudin 4 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Claudin 4 Antibody in Western Blot, Immunohistochemistry (WB, IHC)
          Claudin 4 Antibody in Immunohistochemistry (IHC)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Western Blot (WB)
          Claudin 4 Antibody in Mass Spectrometry (MS)
          Claudin 4 Antibody
          Claudin 4 Antibody

          Product Details

          36-4800

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-3 µg/mL
          View 36 publications 36 publications

          Immunohistochemistry (IHC)

          -
          View 31 publications 31 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          -
          View 4 publications 4 publications

          Immunohistochemistry (Frozen) (IHC (F))

          -
          View 5 publications 5 publications

          Immunocytochemistry (ICC/IF)

          Assay-dependent
          View 20 publications 20 publications

          Flow Cytometry (Flow)

          -
          View 2 publications 2 publications

          ELISA (ELISA)

          0.1-1 µg/mL
          -

          Immunoprecipitation (IP)

          1-3 µg/mL
          -

          Miscellaneous PubMed (MISC)

          -
          View 5 publications 5 publications

          Mass Spectrometry (MS)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Published species

          Dog, Hamster, Human, Mouse, Non-human primate, Pig, Plant, Rat, Sheep

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Clone

          ZMD.306

          Immunogen

          Synthetic peptide derived from the C-terminal region of mouse Claudin-4
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4

          Contains

          0.1% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2533262

          Product Specific Information

          Reactivity has been confirmed with mouse and rat kidney homogenates. On western blots a 22 kDa band is observed and a 44 kDa band representing dimerized protein may be observed.

          Target Information

          Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux. Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl- permeability. In ovarian carcinoma cells, Claudin-3 and Claudin-4 exhibit upregulation at both mRNA and protein levels. Claudin-4 is also overexpressed in pancreatic cancer tissues and cell lines, and in other epithelial cancers. The Claudin-4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Claudin-4; CLAUDIN4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; h CPE-receptor

          View more View less

          Gene Aliases: Cep-r; Cldn4; Cper; Cpetr; Cpetr1

          View more View less

          UniProt ID: (Mouse) O35054

          View more View less

          Entrez Gene ID: (Rat) 304407, (Mouse) 12740

          View more View less

          Function(s)
          molecular_function structural molecule activity protein binding
          Process(es)
          female pregnancy circadian rhythm response to progesterone establishment of skin barrier
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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