Proteintech

Collagen Type IV Polyclonal Antibody

View all (47) Collagen IV antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (4)

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

Collagen Type IV Antibody (55131-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using (Product # 55131-1-AP) (Collagen Type IV antibody) at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using (Product # 55131-1-AP) (Collagen Type IV antibody) at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded Human kidney tissue slide using (Product # 55131-1-AP) Collagen Type IV antibody at dilution of 1:1,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney tissue slide using 55131-1-AP ( Collagen Type IV antibody at dilution of 1:50 (under 40x lens).

Collagen Type IV Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney tissue slide using 55131-1-AP ( Collagen Type IV antibody at dilution of 1:50 (under 10x lens).

Product Details

55131-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 42 publications 42 publications

Immunohistochemistry (IHC)

-

View 20 publications 20 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

-

View 13 publications 13 publications

Miscellaneous PubMed (MISC)

-

View 1 publication 1 publication

Not applicable (N/A)

-

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.39 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M sodium bicarbonate/0.1M glycine, pH 7.3, with 50% glycerol, 0.1M glycine

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific for collagen, type IV, alpha.

Target Information

Collagen IV is a type of collagen protein that is a major component of the basement membrane in various tissues, including the kidneys, lungs, and skin. It forms a network-like structure that provides support and stability to the surrounding tissue. Collagen IV is composed of three alpha chains, which are encoded by the COL4A1, COL4A2, and COL4A3 genes. Mutations in these genes can lead to various genetic disorders, such as Alport syndrome and Goodpasture syndrome, which affect the kidneys and lungs, respectively.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.

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LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.

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LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.

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Li A,Peng R,Sun Y,Liu H,Peng H,Zhang Z

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LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.

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Li A,Peng R,Sun Y,Liu H,Peng H,Zhang Z

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Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.

Molecular therapy. Nucleic acids

Li XY,Wang SS,Han Z,Han F,Chang YP,Yang Y,Xue M,Sun B,Chen LM

Fri Dec 15 00:00:00 UTC 2017

Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.

Molecular therapy. Nucleic acids

Li XY,Wang SS,Han Z,Han F,Chang YP,Yang Y,Xue M,Sun B,Chen LM

Fri Dec 15 00:00:00 UTC 2017

CAPE-pNO₂ ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.

Oncotarget

Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z

Fri Dec 29 00:00:00 UTC 2017

CAPE-pNO₂ ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.

Oncotarget

Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z

Fri Dec 29 00:00:00 UTC 2017

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy.

Cell death & disease

Yi H,Peng R,Zhang LY,Sun Y,Peng HM,Liu HD,Yu LJ,Li AL,Zhang YJ,Jiang WH,Zhang Z

Thu Feb 02 00:00:00 UTC 2017

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy.

Cell death & disease

Yi H,Peng R,Zhang LY,Sun Y,Peng HM,Liu HD,Yu LJ,Li AL,Zhang YJ,Jiang WH,Zhang Z

Thu Feb 02 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: arresten; COL4A1 NC1 domain; Collagen 4; Collagen alpha-1(IV) chain; Collagen alpha-2(IV) chain; Collagen alpha-3(IV) chain; Collagen alpha-4(IV) chain; Collagen alpha-5(IV) chain; Collagen alpha-6(IV) chain; collagen IV, alpha-1 polypeptide; collagen IV, alpha-3 polypeptide; Collagen IV, alpha-4 polypeptide; collagen IV, alpha-5 polypeptide; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-1 chain; collagen of basement membrane, alpha-4 chain; collagen of basement membrane, alpha-5 chain; collagen of basement membrane, alpha-6; collagen, type IV, alpha 1; collagen, type IV, alpha 3 (Goodpasture antigen); collagen, type IV, alpha 4; collagen, type IV, alpha 5; collagen, type IV, alpha 6; dA149D17.3; dA24A23.1; dJ889N15.4 (Collagen Alpha 6(IV)); Goodpasture antigen; tumstatin; Type IV Collagen

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Gene Aliases: ASLN; ATS; BSVD; CA44; CA54; COL4A1; COL4A2; COL4A3; COL4A4; COL4A5; COL4A6; CXDELq22.3; DELXq22.3; DFNX6; ICH; POREN2; RATOR

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UniProt ID: (Human) P02462, (Human) P08572, (Human) Q01955, (Human) P53420, (Human) P29400, (Human) Q14031

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Entrez Gene ID: (Human) 1282, (Human) 1284, (Human) 1285, (Human) 1286, (Human) 1287, (Human) 1288

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extracellular matrix structural constituent protein binding extracellular matrix constituent conferring elasticity platelet-derived growth factor binding integrin binding structural molecule activity metalloendopeptidase inhibitor activity

extracellular matrix organization collagen catabolic process glomerular basement membrane development activation of cysteine-type endopeptidase activity involved in apoptotic process cell adhesion cell surface receptor signaling pathway sensory perception of sound blood circulation cell proliferation negative regulation of cell proliferation negative regulation of endopeptidase activity negative regulation of angiogenesis endothelial cell apoptotic process patterning of blood vessels brain development neuromuscular junction development epithelial cell differentiation blood vessel morphogenesis retinal blood vessel morphogenesis renal tubule morphogenesis cellular response to amino acid stimulus basement membrane organization

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