Proteintech

Collagen Type VI Polyclonal Antibody

Collagen Type VI Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Collagen Type VI Antibody (17023-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human colon tissue slide using (Product # 17023-1-AP) Collagen Type VI antibody at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Collagen Type VI Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Collagen Type VI Antibody in Western Blot (WB)

Collagen Type VI Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17023-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 14 publications 14 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 6 publications 6 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Collagen Type VI Fusion Protein Ag10288 (770-1028 aa encoded by BC052575)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NVISCQGLA PSQGRPGLSL VKENYAELLE DAFLKNVTAQ ICIDKKCPDY TCPITFSSPA DITILLDGSA SVGSHNFDTT KRFAKRLAER FLTAGRTDPA HDVRVAVVQY SGTGQQRPER ASLQFLQNYT ALASAVDAMD FINDATDVND ALGYVTRFYR EASSGAAKKR LLLFSDGNSQ GATPAAIEKA VQEAQRAGIE IFVVVVGRQV NEPHIRVLVT GKTAEYDVAY GESHLFRVPS YQALLRGVFH QTVSRKVALG (770-1028 aa encoded by BC052575)

Target Information

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (typesI, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Exon-Skipping for a Pathogenic COL6A1 Variant in Ullrich Congenital Muscular Dystrophy.

Methods in molecular biology (Clifton, N.J.)

Aguti S,Guirguis F,Bönnemann C,Muntoni F,Bolduc V,Zhou H

Tue Nov 22 00:00:00 UTC 2022

High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer.

Cell cycle (Georgetown, Tex.)

Zhang X,Liu J,Yang X,Jiao W,Shen C,Zhao X,Wang Y

Wed Mar 01 00:00:00 UTC 2023

Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis.

Respiratory physiology & neurobiology

Zhang MH,Han XX,Lu Y,Deng JJ,Zhang WH,Mao JQ,Mi J,Ding WH,Wu MJ,Yu LM,Liu YH

Wed Feb 01 00:00:00 UTC 2023

Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.

Cell death and differentiation

Chen G,Tang Q,Yu S,Shen Y,Sun J,Peng J,Yin Y,Feng G,Lu X,Mei G,Zhang Y,Wan Q,Zhang L,Chen L

Thu Jun 01 00:00:00 UTC 2023

In vivo rAAV-mediated human TGF-β overexpression reduces perifocal osteoarthritis and improves osteochondral repair in a large animal model at one year.

Osteoarthritis and cartilage

Schrenker S,Cucchiarini M,Goebel L,Oláh T,Venkatesan JK,Schmitt G,Speicher-Mentges S,Maihöfer J,Gao L,Zurakowski D,Menger MD,Laschke MW,Madry H

Sat Apr 01 00:00:00 UTC 2023

Skeletal muscle proteome expression differentiates severity of cancer cachexia in mice and identifies loss of fragile X mental retardation syndrome-related protein 1.

Proteomics

Khamoui AV,Tokmina-Roszyk D,Feresin RG,Fields GB,Visavadiya NP

Sun May 01 00:00:00 UTC 2022

Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.

Matrix biology : journal of the International Society for Matrix Biology

Ouni E,Nedbal V,Da Pian M,Cao H,Haas KT,Peaucelle A,Van Kerk O,Herinckx G,Marbaix E,Dolmans MM,Tuuri T,Otala M,Amorim CA,Vertommen D

Sun May 01 00:00:00 UTC 2022

Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis.

American journal of physiology. Heart and circulatory physiology

Angelini A,Ortiz-Urbina J,Trial J,Reddy AK,Malovannaya A,Jain A,Entman ML,Taffet GE,Cieslik KA

Mon Aug 01 00:00:00 UTC 2022

Coaxial structured drug loaded dressing combined with induced stem cell differentiation for enhanced wound healing.

Biomaterials advances

Gao C,Zhang L,Wang J,Cheng Y,Chen Z,Yang R,Zhao G

Tue Mar 01 00:00:00 UTC 2022

Coaxial structured drug loaded dressing combined with induced stem cell differentiation for enhanced wound healing.

Biomaterials advances

Gao C,Zhang L,Wang J,Cheng Y,Chen Z,Yang R,Zhao G

Tue Mar 01 00:00:00 UTC 2022

Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.

Translational oncology

Liu X,Li N,Zhang C,Wu X,Zhang S,Dong G,Liu G

Sun May 01 00:00:00 UTC 2022

Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.

Translational oncology

Liu X,Li N,Zhang C,Wu X,Zhang S,Dong G,Liu G

Sun May 01 00:00:00 UTC 2022

Electroacupuncture remodels the extracellular matrix and promotes synaptic plasticity in a mouse model of depression.

Biochemical and biophysical research communications

Feng Y,Zhu G,Chen R,Shi G,Peng M,Zhou Y,Fu W,Zhou P

Thu Oct 20 00:00:00 UTC 2022

Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress.

Frontiers in physiology

Thant L,Kaku M,Kakihara Y,Mizukoshi M,Kitami M,Arai M,Kitami K,Kobayashi D,Yoshida Y,Maeda T,Saito I,Uoshima K,Saeki M

Sat Jul 16 00:00:00 UTC 2022

The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development.

Development (Cambridge, England)

De A,Morales JE,Chen Z,Sebastian S,McCarty JH

Tue Mar 15 00:00:00 UTC 2022

Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis.

Frontiers in cell and developmental biology

Li M,Li X,Liu B,Lv L,Wang W,Gao D,Zhang Q,Jiang J,Chai M,Yun Z,Tan Y,Gong F,Wu Z,Zhu Y,Ma J,Leng L

Wed Dec 15 00:00:00 UTC 2021

MYCT1 Inhibits the Adhesion and Migration of Laryngeal Cancer Cells Potentially Through Repressing Collagen VI.

Frontiers in oncology

Wang PP,Ding SY,Sun YY,Li YH,Fu WN

Wed Mar 10 00:00:00 UTC 2021

Gapmer Antisense Oligonucleotides to Selectively Suppress the Mutant Allele in COL6A Genes in Dominant Ullrich Congenital Muscular Dystrophy.

Methods in molecular biology (Clifton, N.J.)

Aguti S,Marrosu E,Muntoni F,Zhou H

Fri Mar 19 00:00:00 UTC 2021

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 UTC 2019

Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.

Journal of cellular physiology

Wang H,Ning T,Song C,Luo X,Xu S,Zhang X,Deng Z,Ma D,Wu B

Thu Aug 01 00:00:00 UTC 2019

Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kashpur O,Smith A,Gerami-Naini B,Maione AG,Calabrese R,Tellechea A,Theocharidis G,Liang L,Pastar I,Tomic-Canic M,Mooney D,Veves A,Garlick JA

Tue Jan 01 00:00:00 UTC 2019

Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kashpur O,Smith A,Gerami-Naini B,Maione AG,Calabrese R,Tellechea A,Theocharidis G,Liang L,Pastar I,Tomic-Canic M,Mooney D,Veves A,Garlick JA

Tue Jan 01 00:00:00 UTC 2019

Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kashpur O,Smith A,Gerami-Naini B,Maione AG,Calabrese R,Tellechea A,Theocharidis G,Liang L,Pastar I,Tomic-Canic M,Mooney D,Veves A,Garlick JA

Tue Jan 01 00:00:00 UTC 2019

Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Kashpur O,Smith A,Gerami-Naini B,Maione AG,Calabrese R,Tellechea A,Theocharidis G,Liang L,Pastar I,Tomic-Canic M,Mooney D,Veves A,Garlick JA

Tue Jan 01 00:00:00 UTC 2019

Proteomic analysis of mouse ovaries during the prepubertal stages.

Experimental cell research

Xiong J,Wu M,Zhang Q,Zhang C,Xiong G,Ma L,Lu Z,Wang S

Mon Apr 15 00:00:00 UTC 2019

Differential effect of extracellular matrix derived from papillary and reticular fibroblasts on epidermal development in vitro.

European journal of dermatology : EJD

Janson D,Rietveld M,Mahé C,Saintigny G,El Ghalbzouri A

Thu Jun 01 00:00:00 UTC 2017

Authentication of collagen VI antibodies.

BMC research notes

Endicott J,Holden P,Fitzgerald J

Sat Jul 29 00:00:00 UTC 2017

Authentication of collagen VI antibodies.

BMC research notes

Endicott J,Holden P,Fitzgerald J

Sat Jul 29 00:00:00 UTC 2017

Authentication of collagen VI antibodies.

BMC research notes

Endicott J,Holden P,Fitzgerald J

Sat Jul 29 00:00:00 UTC 2017

Authentication of collagen VI antibodies.

BMC research notes

Endicott J,Holden P,Fitzgerald J

Sat Jul 29 00:00:00 UTC 2017

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

Oncogene

García-Palmero I,Torres S,Bartolomé RA,Peláez-García A,Larriba MJ,Lopez-Lucendo M,Peña C,Escudero-Paniagua B,Muñoz A,Casal JI

Thu Oct 06 00:00:00 UTC 2016

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

Oncogene

García-Palmero I,Torres S,Bartolomé RA,Peláez-García A,Larriba MJ,Lopez-Lucendo M,Peña C,Escudero-Paniagua B,Muñoz A,Casal JI

Thu Oct 06 00:00:00 UTC 2016

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

Oncogene

García-Palmero I,Torres S,Bartolomé RA,Peláez-García A,Larriba MJ,Lopez-Lucendo M,Peña C,Escudero-Paniagua B,Muñoz A,Casal JI

Thu Oct 06 00:00:00 UTC 2016

Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

Oncogene

García-Palmero I,Torres S,Bartolomé RA,Peláez-García A,Larriba MJ,Lopez-Lucendo M,Peña C,Escudero-Paniagua B,Muñoz A,Casal JI

Thu Oct 06 00:00:00 UTC 2016

Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.

Oncotarget

Zhu YP,Wan FN,Shen YJ,Wang HK,Zhang GM,Ye DW

Wed Jun 10 00:00:00 UTC 2015

Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth.

Oncotarget

Zhu YP,Wan FN,Shen YJ,Wang HK,Zhang GM,Ye DW

Wed Jun 10 00:00:00 UTC 2015

Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients.

Oncotarget

Wan F,Wang H,Shen Y,Zhang H,Shi G,Zhu Y,Dai B,Ye D

Tue Sep 29 00:00:00 UTC 2015

Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients.

Oncotarget

Wan F,Wang H,Shen Y,Zhang H,Shi G,Zhu Y,Dai B,Ye D

Tue Sep 29 00:00:00 UTC 2015

A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation.

PloS one

Paez-Cortez J,Krishnan R,Arno A,Aven L,Ram-Mohan S,Patel KR,Lu J,King OD,Ai X,Fine A

Tue Jun 03 00:00:00 UTC 2014

A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation.

PloS one

Paez-Cortez J,Krishnan R,Arno A,Aven L,Ram-Mohan S,Patel KR,Lu J,King OD,Ai X,Fine A

Tue Jun 03 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: alpha 1 (VI) chain (61 AA); Collagen alpha-1(VI) chain; collagen VI, alpha-1 polypeptide; collagen, type VI, alpha 1; procollagen, type VI, alpha 1

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Gene Aliases: AI747156; BTHLM1; Col6a-1; COL6A1; OPLL; RGD1565398; UCHMD1

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UniProt ID: (Human) P12109, (Mouse) Q04857

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Entrez Gene ID: (Human) 1291, (Mouse) 12833, (Rat) 294337

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Function(s)

platelet-derived growth factor binding molecular_function

Process(es)

osteoblast differentiation cell adhesion protein heterotrimerization cellular response to amino acid stimulus biological_process endodermal cell differentiation extracellular matrix organization collagen catabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Collagen Type VI Polyclonal Antibody

Collagen Type VI Antibody (17023-1-AP) in IHC (P)

Product Details

17023-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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