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Product Details
43-9400
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
11A51H12
Immunogen
Bovine Heart Complex III
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533546
Product Specific Information
Positive control: Bovine heart and Human mitochondria
Target Information
Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complex III subunit 1; Complex III subunit 10; Complex III subunit 2; Complex III subunit 3; Complex III subunit 4; Complex III subunit 5; Complex III subunit 6; Complex III subunit 7; Complex III subunit 8; Complex III subunit 9; Complex III subunit III; Complex III subunit IV; Complex III subunit VII; Complex III subunit VIII; Complex III subunit X; Complex III subunit XI; Core protein I; Core protein II; Cytochrome b; Cytochrome b-c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 10; Cytochrome b-c1 complex subunit 2, mitochondrial; Cytochrome b-c1 complex subunit 3; Cytochrome b-c1 complex subunit 4; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 6, mitochondrial; Cytochrome b-c1 complex subunit 7; Cytochrome b-c1 complex subunit 8; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; cytochrome bc-1 complex core protein II; Cytochrome c-1; Cytochrome c1 non-heme 11 kDa protein; Cytochrome c1 non-heme 7 kDa protein; Cytochrome c1, heme protein, mitochondrial; cytochrome C1, nonheme 7kDa protein; low molecular mass ubiquinone-binding protein (9.5kD); Mitochondrial hinge protein; mitochondrial ubiquinone-binding protein; QP-C; Rieske iron-sulfur protein; Rieske protein UQCRFS1; RISP; ubiquinol cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase (6.4kD) subunit; ubiquinol-cytochrome c reductase complex (7.2 kD); Ubiquinol-cytochrome c reductase complex 11 kDa protein; Ubiquinol-cytochrome c reductase complex 14 kDa protein; Ubiquinol-cytochrome c reductase complex 6.4 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase, complex III subunit VI; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; ubiquinol-cytochrome c reductase, complex III subunit VIII; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa; Ubiquinol-cytochrome-c reductase complex core protein 1; Ubiquinol-cytochrome-c reductase complex core protein 2; Ubiquinol-cytochrome-c reductase complex cytochrome b subunit; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit
Gene Aliases: 0710008D09Rik; BOS_13658; BOS_14114; BOS_16735; BOS_16926; BOS_20929; BOS_22740; BOS_3696; BOS_8034; BOS_8119; COB; CYC1; CYTB; D3S3191; HSPC051; HSPC119; HSPC151; MC3DN3; MC3DN4; MC3DN5; MC3DN6; MT-CYB; MTCYB; QCR1; QCR10; QCR2; QCR6; QCR7; QCR8; QCR9; QP-C; QPC; RIP1; RIS1; RISP; UCCR7.2; UCRC; UQBC; UQBP; UQCR; UQCR1; UQCR10; UQCR11; UQCR2; UQCR4; UQCR5; UQCR6; UQCR7; UQCR8; UQCRB; UQCRC1; UQCRC2; UQCRFS1; UQCRH; UQCRQ; UQPC
heme binding
electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
metal ion binding
iron ion binding
electron carrier activity
ubiquinol-cytochrome-c reductase activity
protein binding
catalytic activity
metalloendopeptidase activity
zinc ion binding
ubiquitin protein ligase binding
protein complex binding
2 iron, 2 sulfur cluster binding
proteolysis
electron transport chain
generation of precursor metabolites and energy
mitochondrial electron transport, ubiquinol to cytochrome c
hydrogen ion transmembrane transport
response to glucagon
oxidative phosphorylation
aerobic respiration
response to activity
protein processing
response to alkaloid
oxidation-reduction process
mitochondrial respiratory chain complex III assembly
response to hormone
response to drug
response to antibiotic
subthalamus development
pons development
cerebellar Purkinje cell layer development
hippocampus development
thalamus development
hypothalamus development
pyramidal neuron development
midbrain development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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