Product References
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice.
EBioMedicine
Peres C,Sellitto C,Nardin C,Putti S,Orsini T,Di Pietro C,Marazziti D,Vitiello A,Calistri A,Rigamonti M,Scavizzi F,Raspa M,Zonta F,Yang G,White TW,Mammano F
71-2200 was used in Immunohistochemistry to show that AAVmAb treatment eliminated abnormal keratinocyte proliferation and enlarged cell size, decreased apoptosis, and restored the normal distribution of keratin expression.
Wed Mar 01 00:00:00 UTC 2023
Cx26 heterozygous mutations cause hyperacusis-like hearing oversensitivity and increase susceptibility to noise.
Science advances
Liu LM,Liang C,Chen J,Fang S,Zhao HB
71-2200 was used in Immunohistochemistry to indicate that GJB2 hetero-mutation carriers are vulnerable to noise and should avoid noise exposure in daily life.
Fri Feb 10 00:00:00 UTC 2023
Upregulation of astroglial connexin 30 impairs hippocampal synaptic activity and recognition memory.
PLoS biology
Hardy E,Moulard J,Walter A,Ezan P,Bemelmans AP,Mouthon F,Charvériat M,Rouach N,Rancillac A
71-2200 was used in Immunohistochemistry to suggest that astroglial networks have a physiologically optimized size to appropriately regulate neuronal functions.
Sat Apr 01 00:00:00 UTC 2023
Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice.
Frontiers in cell and developmental biology
Zhang L,Wang W,Kim SM,Wang J,Zhou B,Kong W,Zheng J,Lin X
71-2200 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to demonstrate the first successful cochlear gene therapy treatment in mouse models by virally expressing a companion gene of Gjb6.
Thu Aug 04 00:00:00 UTC 2022
Microglia maintain the normal structure and function of the hippocampal astrocyte network.
Glia
Du Y,Brennan FH,Popovich PG,Zhou M
71-2200 was used in Immunohistochemistry-immunofluorescence to reveal the importance of microglia in homeostatic regulation of the astrocyte syncytium and scaling of synaptic transmission.
Fri Jul 01 00:00:00 UTC 2022
Physiological synaptic activity and recognition memory require astroglial glutamine.
Nature communications
Cheung G,Bataveljic D,Visser J,Kumar N,Moulard J,Dallérac G,Mozheiko D,Rollenhagen A,Ezan P,Mongin C,Chever O,Bemelmans AP,Lübke J,Leray I,Rouach N
71-2200 was used in Western Blot to show that the role of glutamine is dependent on the opening of astroglial connexin 43 hemichannels upon activity, and provide evidence for the functional relevance of astroglial glutamine in physiological synaptic transmission and cognition.
Tue Feb 08 00:00:00 UTC 2022
Beneficial contribution of induced pluripotent stem cell-progeny to Connexin 47 dynamics during demyelination-remyelination.
Glia
Mozafari S,Deboux C,Laterza C,Ehrlich M,Kuhlmann T,Martino G,Baron-Van Evercooren A
71-2200 was used in Immunocytochemistry-immunoflourescence to investigate the expression dynamics of the oligodendrocyte specific connexin 47 (Cx47) and to some extent that of astrocyte Cx43, and whether this dynamic could be modulated by grafted induced pluripotent stem cell (iPSC)-neural progeny.
Sat May 01 00:00:00 UTC 2021
Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells.
Frontiers in cell and developmental biology
Fukunaga I,Oe Y,Chen C,Danzaki K,Ohta S,Koike A,Ikeda K,Kamiya K
71-2200 was used in Immunocytochemistry to demonstrate that Activin/Nodal/TGF-β pathway inhibitor SB431542 accelerates BMP4-induced iCX26GJC (induced CX26 gap junction-forming cells) differentiation during stem cell floating culture.
Tue Apr 02 00:00:00 UTC 2024
Dynamic Spatiotemporal Expression Changes in Connexins of the Developing Primate's Cochlea.
Genes
Hosoya M,Fujioka M,Murayama AY,Ogawa K,Okano H,Ozawa H
71-2200 was used in Immunohistochemistry to examine expression patterns of connexin 26 and connexin 30 in the developing cochlea of a common marmoset as a way to investigate genetic deafness in humans.
Fri Jul 16 00:00:00 UTC 2021
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture.
Nature communications
Lattke M,Goldstone R,Ellis JK,Boeing S,Jurado-Arjona J,Marichal N,MacRae JI,Berninger B,Guillemot F
71-2200 was used in Immunohistochemistry to conclude that extrinsic signals orchestrate the expression of multiple intrinsic regulators, which in turn induce in a modular manner the transcriptional and chromatin changes underlying astrocyte maturation.
Thu Jul 15 00:00:00 UTC 2021
Spike Generators and Cell Signaling in the Human Auditory Nerve: An Ultrastructural, Super-Resolution, and Gene Hybridization Study.
Frontiers in cellular neuroscience
Liu W,Luque M,Li H,Schrott-Fischer A,Glueckert R,Tylstedt S,Rajan G,Ladak H,Agrawal S,Rask-Andersen H
71-2200 was used in Immunohistochemistry to gain information about the molecular instruments in human auditory nerve processing and deviations, and ways to perform electric modeling of prosthetic devices.
Sat Nov 11 00:00:00 UTC 2023
Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability.
Scientific reports
Cibelli A,Stout R,Timmermann A,de Menezes L,Guo P,Maass K,Seifert G,Steinhäuser C,Spray DC,Scemes E
71-2200 was used in Immunohistochemistry-immunofluorescence to support the hypothesis that localization and mobility of gap junction proteins and their binding partners influences organization of astrocyte endfeet which in turn impacts BBB integrity of the NVU.
Tue Dec 21 00:00:00 UTC 2021
Degradation and modification of cochlear gap junction proteins in the early development of age-related hearing loss.
Experimental & molecular medicine
Tajima S,Danzaki K,Ikeda K,Kamiya K
71-2200 was used in Immunohistochemistry to investigate the quantitative change in expression and molecular pathology of Cx26 in age-related hearing loss (ARHL).
Wed Jan 01 00:00:00 UTC 2020
Connexin Signaling Is Involved in the Reactivation of a Latent Stem Cell Niche after Spinal Cord Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fabbiani G,Reali C,Valentín-Kahan A,Rehermann MI,Fagetti J,Falco MV,Russo RE
71-2200 was used in Immunohistochemistry to study the role of connexin signalling in the central canal in the reactivation of latent stem cell after spinal cord injury.
Wed Mar 11 00:00:00 UTC 2020
GJB2 Mutations Linked to Hearing Loss Exhibit Differential Trafficking and Functional Defects as Revealed in Cochlear-Relevant Cells.
Frontiers in cell and developmental biology
Beach R,Abitbol JM,Allman BL,Esseltine JL,Shao Q,Laird DW
71-2200 was used in Immunocytochemistry-immunoflourescence to assess if common or divergent mechanisms are at the root of GJB2-linked hearing loss.
Thu Mar 28 00:00:00 UTC 2024
GJB2 Mutations Linked to Hearing Loss Exhibit Differential Trafficking and Functional Defects as Revealed in Cochlear-Relevant Cells.
Frontiers in cell and developmental biology
Beach R,Abitbol JM,Allman BL,Esseltine JL,Shao Q,Laird DW
71-2200 was used in Immunocytochemistry-immunoflourescence to assess if common or divergent mechanisms are at the root of GJB2-linked hearing loss.
Thu Mar 28 00:00:00 UTC 2024
Neuronal Activity Drives Astroglial Connexin 30 in Perisynaptic Processes and Shapes Its Functions.
Cerebral cortex (New York, N.Y. : 1991)
Ghézali G,Vasile F,Curry N,Fantham M,Cheung G,Ezan P,Cohen-Salmon M,Kaminski C,Rouach N
71-2200 was used in Immunohistochemistry to show activity-dependent dynamics of Cx30 expression, perisynaptic localisation and functions.
Sat Mar 21 00:00:00 UTC 2020
A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels.
The Journal of general physiology
Gaete PS,Lillo MA,López W,Liu Y,Jiang W,Luo Y,Harris AL,Contreras JE
71-2200 was used in Western Blotting to develop a novel technique that allows kinetic analysis of molecular permeation through connexin and CALHM1 channels in Xenopus oocytes rendered translucent.
Mon Nov 02 00:00:00 UTC 2020
Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes.
Biomolecules
Au A,Shao Q,White KK,Lucaciu SA,Esseltine JL,Barr K,Laird DW
71-2200 was used in Immunocytochemistry-immunoflourescence to study the role of the principal connexin Cx43 in rodent keratinocyte differentiation.
Wed Oct 14 00:00:00 UTC 2020
Stress gates an astrocytic energy reservoir to impair synaptic plasticity.
Nature communications
Murphy-Royal C,Johnston AD,Boyce AKJ,Diaz-Castro B,Institoris A,Peringod G,Zhang O,Stout RF,Spray DC,Thompson RJ,Khakh BS,Bains JS,Gordon GR
71-2200 was used in Western Blotting to show in mice that stress constrains the shuttling of glucose and lactate through astrocyte networks, creating a barrier for neuronal access to an astrocytic energy reservoir in the hippocampus and neocortex, compromising long-term potentiation.
Fri Apr 24 00:00:00 UTC 2020
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.
EBioMedicine
Kuang Y,Zorzi V,Buratto D,Ziraldo G,Mazzarda F,Peres C,Nardin C,Salvatore AM,Chiani F,Scavizzi F,Raspa M,Qiang M,Chu Y,Shi X,Li Y,Liu L,Shi Y,Zonta F,Yang G,Lerner RA,Mammano F
71-2200 was used in Immunohistochemistry-immunofluorescence to study the in vivo efficacy of potent antagonist antibodies targeting connexin hemichannels which could be used to treat Clouston syndrome.
Wed Jul 01 00:00:00 UTC 2020
Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication.
Cell death & disease
Abitbol J,Beach R,Barr K,Esseltine J,Allman B,Laird D
71-2200 was used in Immunocytochemistry-immunoflourescence to investigate the role of Cx43 in cisplatin-induced ototoxicity using organotypic cochlear cultures from control and two Cx43-mutant mouse strains harboring either a moderate (Cx43I130T/+) or severe (Cx43G60S/+) reduction of Cx43 function.
Mon May 11 00:00:00 UTC 2020
Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.
Journal of the Association for Research in Otolaryngology : JARO
Huebner AK,Maier H,Maul A,Nietzsche S,Herrmann T,Praetorius J,Hübner CA
71-2200 was used in Immunohistochemistry to study the timeline of Slc4a10/Nbcn2 expression during sensory transduction in the inner ear using a mouse model.
Sat Jun 01 00:00:00 UTC 2019
Generation of Functional CX26-Gap-Junction-Plaque-Forming Cells with Spontaneous Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.
Current protocols in stem cell biology
Fukunaga I,Fujimoto A,Hatakeyama K,Kurebayashi N,Ikeda K,Kamiya K
71-2200 was used in Immunocytochemistry to detail a novel strategy for differentiating iPS cells into functional Cx26GJCs such as are found in cochlea.
Sun Dec 01 00:00:00 UTC 2019
Hearing consequences in Gjb2 knock-in mice: implications for human p.V37I mutation.
Aging
Lin X,Li G,Zhang Y,Zhao J,Lu J,Gao Y,Liu H,Li GL,Yang T,Song L,Wu H
71-2200 was used in Immunohistochemistry to investigated the impact of three environmental risk factors, noise, ototoxic drug, and the disruption of ionic homeostasis in the cochlea, and found that they all accelerated the disease progression though examining tissue-specific pathology.
Fri Sep 27 00:00:00 UTC 2019
Chronic Unpredictable Stress Reduces Immunostaining for Connexins 43 and 30 and Myelin Basic Protein in the Rat Prelimbic and Orbitofrontal Cortices.
Chronic stress (Thousand Oaks, Calif.)
Miguel-Hidalgo JJ,Moulana M,Deloach PH,Rajkowska G
71-2200 was used in Immunohistochemistry to examine how exposure to chronic unpredictable stress affects Connexins 43 and 30 and Myelin Basic Protein in rat prelimbic cortex and orbitofrontal cortex.
Thu Mar 31 00:00:00 UTC 2022
mCCDcl1 cells show plasticity consistent with the ability to transition between principal and intercalated cells.
American journal of physiology. Renal physiology
Assmus AM,Mansley MK,Mullins LJ,Peter A,Mullins JJ
71-2200 was used in Immunocytochemistry-immunoflourescence to show mCCDcl1 cells may be able to mediate principal to intercalated cell transition.
Tue May 01 00:00:00 UTC 2018
Permeant-specific gating of connexin 30 hemichannels.
The Journal of biological chemistry
Nielsen BS,Alstrom JS,Nicholson BJ,Nielsen MS,MacAulay N
71-2200 was used in Western Blotting to show that the permeability of hemichannels is regulated in a permeant-specific manner and demonstrate the selectivity of hemichannels.
Fri Dec 08 00:00:00 UTC 2017
Differential expression of astrocytic connexins in a mouse model of prenatal alcohol exposure.
Neurobiology of disease
Ramani M,Mylvaganam S,Krawczyk M,Wang L,Zoidl C,Brien J,Reynolds JN,Kapur B,Poulter MO,Zoidl G,Carlen PL
71-2200 was used in immunohistochemistry - frozen section and western blot to study differential expression of astrocytic connexins by a prenatal alcohol exposure mouse model
Fri Jul 01 00:00:00 UTC 2016
Connexin gap junction channels and chronic rhinosinusitis.
International forum of allergy & rhinology
Kim R,Chang G,Hu R,Phillips A,Douglas R
71-2200 was used in immunohistochemistry - frozen section to learn the connection between chronic rhinosinusitis and connexin gap junction channels
Wed Jun 01 00:00:00 UTC 2016
Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea: the Connexin26/30 proteins are separately expressed in man.
Cell and tissue research
Liu W,Edin F,Blom H,Magnusson P,Schrott-Fischer A,Glueckert R,Santi PA,Li H,Laurell G,Rask-Andersen H
71-2200 was used in immunohistochemistry - frozen section to assess the lateral wall of the cochlea and connexin26/30 proteins and separate expression in man by using super-resolution structured illumination fluorescence microscopy
Fri Jul 01 00:00:00 UTC 2016
Connexins, E-cadherin, Claudin-7 and β-catenin transiently form junctional nexuses during the post-natal mammary gland development.
Developmental biology
Dianati E,Poiraud J,Weber-Ouellette A,Plante I
71-2200 was used in western blot to assess the transiently formed junctional nexuses during post-natal mammary gland development by E-cadherins, connexins, beta-catenin, and claudin-7
Mon Aug 01 00:00:00 UTC 2016
Connexin43 and connexin47 alterations after neural precursor cells transplantation in experimental autoimmune encephalomyelitis.
Glia
Theotokis P,Kleopa KA,Touloumi O,Lagoudaki R,Lourbopoulos A,Nousiopoulou E,Kesidou E,Poulatsidou KN,Dardiotis E,Hadjigeorgiou G,Karacostas D,Cifuentes-Diaz C,Irinopoulou T,Grigoriadis N
71-2200 was used in immunohistochemistry (frozen) to investigate the effects of transplanted neural precursor cells in the chronic MOG-induced experimental autoimmune encephalomyelitis model.
Thu Oct 01 00:00:00 UTC 2015
Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions.
Journal of cell science
Kelly JJ,Shao Q,Jagger DJ,Laird DW
71-2200 was used in immunocytochemistry and western blot to study the synthesis and localization of connexin 30.
Sun Nov 01 00:00:00 UTC 2015
Effects of sleep and wake on astrocytes: clues from molecular and ultrastructural studies.
BMC biology
Bellesi M,de Vivo L,Tononi G,Cirelli C
71-2200 was used in western blot to examine the effects of sleep and wake on astrocytes
Tue Aug 25 00:00:00 UTC 2015
Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice.
Frontiers in cellular neuroscience
Quesseveur G,Portal B,Basile JA,Ezan P,Mathou A,Halley H,Leloup C,Fioramonti X,Déglon N,Giaume C,Rampon C,Guiard BP
71-2200 was used in Western Blotting to investigate the role of hippocampal Cx43 in the regulation of depression-like symptoms using genetic and pharmacological approaches.
Wed Jan 06 00:00:00 UTC 2016
Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing.
Scientific reports
Chen J,Zhu Y,Liang C,Chen J,Zhao HB
71-2200 was used in immunohistochemistry to study how Panx1 channels regulate ATP release in the cochlea.
Tue Jun 02 00:00:00 UTC 2015
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion.
Nature neuroscience
Pannasch U,Freche D,Dallérac G,Ghézali G,Escartin C,Ezan P,Cohen-Salmon M,Benchenane K,Abudara V,Dufour A,Lübke JH,Déglon N,Knott G,Holcman D,Rouach N
71-2200 was used in immunohistochemistry to show that connexin 30 controls hippocampal excitatory synaptic transmission through modulation of astroglial glutamate transport.
Tue Apr 01 00:00:00 UTC 2014
Gap junctional coupling is essential for epithelial repair in the avian cochlea.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jagger DJ,Nickel R,Forge A
71-2200 was used in immunocytochemistry to study the role of gap junctional coupling in epithelial repair in the avian cochlea
Wed Nov 26 00:00:00 UTC 2014
Expression of gap junction proteins connexins 26, 30, and 43 in Dupuytren's disease.
Acta orthopaedica
Holzer LA,Cör A,Holzer G
71-2200 was used in immunohistochemistry - frozen section to investigate the expression of gap junction proteins in Dupuytren disease
Sat Feb 01 00:00:00 UTC 2014
The Clouston syndrome mutation connexin30 A88V leads to hyperproliferation of sebaceous glands and hearing impairments in mice.
FEBS letters
Bosen F,Schütz M,Beinhauer A,Strenzke N,Franz T,Willecke K
71-2200 was used in immunohistochemistry to investigate the effect of the Clouston syndrome mutation connexin30 A88V on the proliferation of sebaceous glands and hearing in mice
Fri May 02 00:00:00 UTC 2014
Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia.
Neuropharmacology
Kozoriz MG,Lai S,Vega JL,Sáez JC,Sin WC,Bechberger JF,Naus CC
71-2200 was used in western blot to assess the effect of the +/G60S mutation in connexin 43 following stroke.
Sun Dec 01 00:00:00 UTC 2013
Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea.
Journal of cell science
Forge A,Jagger DJ,Kelly JJ,Taylor RR
71-2200 was used in immunohistochemistry - frozen section to determine the role of connexin 30 in epithelial repair following injury in the organ of Corti.
Mon Apr 01 00:00:00 UTC 2013
Connexin dynamics in the privileged wound healing of the buccal mucosa.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Davis NG,Phillips A,Becker DL
71-2200 was used in immunohistochemistry - frozen section to determine connexin changes during check wound healing.
Wed Feb 19 00:00:00 UTC 2014
Spatiotemporal changes in Cx30 and Cx43 expression during neuronal differentiation of P19 EC and NT2/D1 cells.
Cell biology international reports
Wan CK,O'Carroll SJ,Kim SL,Green CR,Nicholson LF
71-2200 was used in immunocytochemistry to examine the expression and roles Cx30, Cx36, and Cx43 in neuronal differentiation
Sun Dec 01 00:00:00 UTC 2013
Comparison of bidirectional and bicistronic inducible systems for coexpression of connexin genes and fluorescent reporters.
Analytical biochemistry
Wan CK,Shaikh SB,Green CR,Nicholson LF
71-2200 was used in immunocytochemistry to study Cx30 and Cx43 using inducible expression systems.
Sat Dec 15 00:00:00 UTC 2012
Functional heterotypic interactions between astrocyte and oligodendrocyte connexins.
Glia
Magnotti LM,Goodenough DA,Paul DL
Sat Jan 01 00:00:00 UTC 2011
Connexin32 can restore hearing in connexin26 deficient mice.
European journal of cell biology
Degen J,Schütz M,Dicke N,Strenzke N,Jokwitz M,Moser T,Willecke K
71-2200 was used in immunocytochemistry to study connexin 26 and connexin 32 isoforms in the cochlea.
Sat Oct 01 00:00:00 UTC 2011
The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome.
Human molecular genetics
Schütz M,Auth T,Gehrt A,Bosen F,Körber I,Strenzke N,Moser T,Willecke K
71-2200 was used in immunohistochemistry to study the Cx26S17F mutation in mice
Sat Jan 01 00:00:00 UTC 2011
BAAV mediated GJB2 gene transfer restores gap junction coupling in cochlear organotypic cultures from deaf Cx26Sox10Cre mice.
PloS one
Crispino G,Di Pasquale G,Scimemi P,Rodriguez L,Galindo Ramirez F,De Siati RD,Santarelli RM,Arslan E,Bortolozzi M,Chiorini JA,Mammano F
71-2200 was used in immunohistochemistry to study the expression and function of connexin26 and connexin30 in the ears of transgenic mice.
Fri Dec 30 00:00:00 UTC 2011
Dominant connexin26 mutants associated with human hearing loss have trans-dominant effects on connexin30.
Neurobiology of disease
Yum SW,Zhang J,Scherer SS
71-2200 was used in immunocytochemistry to test if dominant Cx26 mutants interact directly with Cx30
Sat May 01 00:00:00 UTC 2010
Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus.
Neurobiology of disease
Takahashi DK,Vargas JR,Wilcox KS
71-2200 was used in western blot to test if hippocampal astrocytes have altered function soon after kainic acid-induced status epilepticus
Wed Dec 01 00:00:00 UTC 2010
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.
Human molecular genetics
Schütz M,Scimemi P,Majumder P,De Siati RD,Crispino G,Rodriguez L,Bortolozzi M,Santarelli R,Seydel A,Sonntag S,Ingham N,Steel KP,Willecke K,Mammano F
71-2200 was used in immunohistochemistry and western blot to create and characterize a mouse model for human bilateral middle/high-frequency hearing loss
Wed Dec 15 00:00:00 UTC 2010
Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Neuroscience
Mei X,Ezan P,Giaume C,Koulakoff A
71-2200 was used in immunohistochemistry to determine the expression pattern of connexin43 and 30 in two murine models of Alzheimer disease
Wed Nov 24 00:00:00 UTC 2010
Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.
Histochemistry and cell biology
Haass NK,Ripperger D,Wladykowski E,Dawson P,Gimotty PA,Blome C,Fischer F,Schmage P,Moll I,Brandner JM
71-2200 was used in immunohistochemistry - paraffin section to study Cx26, Cx30, and Cx43 expression in the epidermal microenvironment of melanocytic nevi and melanomas
Fri Jan 01 00:00:00 UTC 2010
The connexin43 C-terminal region mediates neuroprotection during stroke.
Journal of neuropathology and experimental neurology
Kozoriz MG,Bechberger JF,Bechberger GR,Suen MW,Moreno AP,Maass K,Willecke K,Naus CC
71-2200 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to suggest that astrocytic Cx43 contributed to the regulation of cell death after stroke and support the view that the Cx43 C-terminal region is important in protection in cerebral ischemia.
Mon Feb 01 00:00:00 UTC 2010
Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality.
Journal of cellular and molecular medicine
Wang HX,Tong D,El-Gehani F,Tekpetey FR,Kidder GM
Fri May 01 00:00:00 UTC 2009
Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality.
Journal of cellular and molecular medicine
Wang HX,Tong D,El-Gehani F,Tekpetey FR,Kidder GM
Fri May 01 00:00:00 UTC 2009
Unique expression of connexins in the human cochlea.
Hearing research
Liu W,Boström M,Kinnefors A,Rask-Andersen H
71-2200 was used in immunohistochemistry - frozen section to analyze the expression and distribution of connexin 26 and connexin 30 in normal human cochleae
Wed Apr 01 00:00:00 UTC 2009
Tissue-specific cross-reactivity of connexin32 antibodies: problems and solutions unique to the central nervous system.
Cell communication & adhesion
Fowler SL,McLean AC,Bennett SA
71-2200 was used in western blot to discuss the limitations of using antibodies to study connexin 32 expression in the central nervous system
Tue Dec 01 00:00:00 UTC 2009
Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes.
Glia
Koulakoff A,Ezan P,Giaume C
71-2200 was used in immunocytochemistry, immunohistochemistry, and western blot to test if astrocyte connexins are regulated by neurons
Mon Sep 01 00:00:00 UTC 2008
Cellular characterization of Connexin26 and Connnexin30 expression in the cochlear lateral wall.
Cell and tissue research
Liu YP,Zhao HB
71-2200 was used in immunocytochemistry to examine the cellular expression of connexin 26 and 30 in the cochlear lateral wall of rats and guinea pigs
Mon Sep 01 00:00:00 UTC 2008
Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow.
The Journal of comparative neurology
Kuo IY,Chan-Ling T,Wojcikiewicz RJ,Hill CE
71-2200 was used in immunohistochemistry to study the extent of coupling in microvessels of the rodent brainstem and retina and the subtypes of intracellular calcium stores that mediate astrocytic signaling.
Sat Dec 20 00:00:00 UTC 2008
Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nelson RF,Glenn KA,Zhang Y,Wen H,Knutson T,Gouvion CM,Robinson BK,Zhou Z,Yang B,Smith RJ,Paulson HL
71-2200 was used in immunohistochemistry - paraffin section and western blot to investigate the role of Fbx2 in ear homeostasis
Wed May 09 00:00:00 UTC 2007
Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Haass NK,Wladykowski E,Kief S,Moll I,Brandner JM
71-2200 was used in immunohistochemistry - paraffin section to report that connexin 26 and connexin 30 induced in keratinocyte-derived epithelial skin tumors
Wed Feb 01 00:00:00 UTC 2006
Gap junctional coupling and connexin immunoreactivity in rabbit retinal glia.
Visual neuroscience
Zahs KR,Ceelen PW
71-2200 was used in immunohistochemistry - frozen section to study connexins in mammalian Muller cells
Mon Jun 05 00:00:00 UTC 2006
In vivo and in vitro expression of connexins in the human corneal epithelium.
Investigative ophthalmology & visual science
Shurman DL,Glazewski L,Gumpert A,Zieske JD,Richard G
Wed Jun 01 00:00:00 UTC 2005
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
The European journal of neuroscience
Penes MC,Li X,Nagy JI
Fri Jul 01 00:00:00 UTC 2005
Postnatal development of GFAP, connexin43 and connexin30 in cat visual cortex.
Brain research. Developmental brain research
Rochefort N,Quenech'du N,Ezan P,Giaume C,Milleret C
71-2200 was used in immunohistochemistry - free floating to investigate the development of astrocytes in the cat visual cortex
Wed Dec 07 00:00:00 UTC 2005
The relationship between connexins, gap junctions, tissue architecture and tumour invasion, as studied in a novel in vitro model of HPV-16-associated cervical cancer progression.
Oncogene
Aasen T,Hodgins MB,Edward M,Graham SV
71-2200 was used in immunocytochemistry to examine the relationships among HPV infection, gap junctions, and tumor progression.
Thu Sep 11 00:00:00 UTC 2003
Targeted epidermal expression of mutant Connexin 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders.
Human molecular genetics
Bakirtzis G,Choudhry R,Aasen T,Shore L,Brown K,Bryson S,Forrow S,Tetley L,Finbow M,Greenhalgh D,Hodgins M
71-2200 was used in immunohistochemistry - frozen section to study the role of connexin 26 in dominantly inherited skin disease.
Tue Jul 15 00:00:00 UTC 2003
Microglia and astrocytes may participate in the shaping of visual callosal projections during postnatal development.
Journal of physiology, Paris
Rochefort N,Quenech'du N,Watroba L,Mallat M,Giaume C,Milleret C
71-2200 was used in immunohistochemistry to study postnatal development of neuronal projections using cats.
Fri Apr 04 00:00:00 UTC 2003
Expression and function of astrocytic gap junctions in aging.
Brain research
Cotrina ML,Gao Q,Lin JH,Nedergaard M
71-2200 was used in immunohistochemistry - frozen section to measure astrocytic gap junction proteins in young and senescent brains and quantify the extent of functional gap junction coupling
Fri May 18 00:00:00 UTC 2001
