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Invitrogen
Copeptin Recombinant Rabbit Monoclonal Antibody (20H24L10)
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Product Details
701297
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
20H24L10
Immunogen
Peptide corresponding to amino acids 126-164 of human copeptin
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2532465
Product Specific Information
This antibody is predicted to react with bovine, canine, chimpanzee, non-human primate, rabbit, ovine and porcine based on sequence homology.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Copeptin is a member of vasopressin/oxytocin family. It is a 39-amino acid peptide produced from cleavage of preprovasopressin during precursor processing, and is released along with the hormone arginine vasopressin. Copeptin acts to ensure the proper structural formation of arginine vasopressin during precursor processing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antidiuretic hormone; AVP-NPII; copeptin; neurohypophyseal; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin
Gene Aliases: ADH; ARVP; AVP; AVP-NPII; AVRP; VP
UniProt ID: (Human) P01185
Entrez Gene ID: (Human) 551
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
renal water homeostasis
generation of precursor metabolites and energy
water transport
apoptotic process
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of female receptivity
grooming behavior
locomotory behavior
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of cell growth
positive regulation of cAMP biosynthetic process
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
positive regulation of peptidyl-serine phosphorylation
response to testosterone
response to nicotine
social behavior
regulation of renal sodium excretion
vasoconstriction
hyperosmotic salinity response
maternal behavior
negative regulation of apoptotic process
penile erection
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
sodium-independent organic anion transport
response to ethanol
positive regulation of vasoconstriction
negative regulation of transmission of nerve impulse
ERK1 and ERK2 cascade
protein kinase C signaling
negative regulation of release of cytochrome c from mitochondria
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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