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Bethyl Laboratories
Coronin 1 Polyclonal Antibody
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FIGURE: 1 / 2
Coronin 1 Antibody (A300-931A) in IHC (P)
Detection of human and mouse Coronin 1 by immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor (left) and mouse fibroma (right). Antibody: Affinity purified rabbit anti-Coronin 1 (Product # A300-931A) (Lot 1) used at a dilution of 1:200 (1 µg/mL) and 1:1,000 (0.2 µg/mL). Detection: DAB.
Product Details
A300-931A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 250 and 300 of human Coronin 1 (Coronin, Actin Binding Protein 1A).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding; Clabp coronin; Clipin-A; coronin 1; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; coronin-like actin binding protein; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
Gene Aliases: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; Lmb3; p57; TACO
UniProt ID: (Human) P31146, (Mouse) O89053
Entrez Gene ID: (Human) 11151, (Mouse) 12721
immunological synapse formation
phagolysosome assembly
calcium ion transport
phagocytosis
movement of cell or subcellular component
actin filament organization
regulation of cell shape
actin cytoskeleton organization
positive regulation of cell migration
leukocyte chemotaxis
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
positive regulation of T cell proliferation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
cellular response to interleukin-4
regulation of actin polymerization or depolymerization
cell migration
regulation of actin filament polymerization
response to cytokine
positive regulation of T cell activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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