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Invitrogen
Coronin 1A Polyclonal Antibody
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FIGURE: 1 / 8
Coronin 1A Antibody (PA1-10022) in ICC/IF
Immunofluorescent analysis of cortical neuron-glial cell culture from E20 rat stained with rabbit pAb to coronin 1a (Product # PA1-10022, diluted 1:1,000) in red, and costained with mouse mAb to GFAP (diluted 1:1,000) in green. The blue is Hoechst staining of nuclear DNA. The coronin 1a antibody labels protein expressed in the cytoplasm of microglia cells, while GFAP antibody stains intermediate filaments i... View More
Product Details
PA1-10022
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Pig,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C-terminal peptide of human coronin 1a coupled to KLH
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2082069
Product Specific Information
PA1-10022 was made against the C-terminal peptide of human coronin 1a chemically coupled to keyhole limpet hemocyanin carrier protein. PA1-10022 is also known to work on many mammalian species both on western blots and on cells grown in tissue culture.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin-binding; Clabp coronin; Clipin-A; coronin 1; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; coronin-like actin binding protein; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
Gene Aliases: BOS_22845; CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; Lmb3; p57; TACO
UniProt ID: (Bovine) Q92176, (Human) P31146, (Mouse) O89053, (Rat) Q91ZN1
Entrez Gene ID: (Bovine) 282196, (Human) 11151, (Mouse) 12721, (Rat) 155151
phagolysosome assembly
calcium ion transport
actin filament organization
regulation of cell shape
positive regulation of cell migration
leukocyte chemotaxis
regulation of actin filament polymerization
cell-substrate adhesion
uropod organization
positive regulation of T cell proliferation
T cell homeostasis
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
cellular response to interleukin-4
immunological synapse formation
phagocytosis
movement of cell or subcellular component
actin cytoskeleton organization
negative regulation of vesicle fusion
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
regulation of actin polymerization or depolymerization
cell migration
response to cytokine
positive regulation of T cell activation
biological_process
T cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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