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Invitrogen
Coronin 2A Polyclonal Antibody
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Coronin 2A Antibody (PA5-59458) in IHC
Immunohistochemical staining of Coronin 2A in human kidney, lymph node, small intestine and testis using Coronin 2A Polyclonal Antibody (Product # PA5-59458) (A) shows similar protein distribution across tissues to an independent Coronin 2A Polyclonal Antibody (B).
Product Details
PA5-59458
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Coronin 2A. Recombinant protein control fragment (Product #RP-98381).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640079
Product Specific Information
Immunogen sequence: DIYPPTAGAQ PSLTAQEWLS GMNRDPILVS LRPGSELLRP HPLPAERPIF NSMAPASPRL LNQTEKLAAE DGW
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 66%.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coronin, actin binding protein, 2A; coronin, actin-binding protein, 2A; Coronin-2A; coronin-like protein B; IR10; WD protein IR10; WD repeat-containing protein 2; WD-repeat protein 2
Gene Aliases: CLIPINB; CORO2A; IR10; WDR2
UniProt ID: (Human) Q92828
Entrez Gene ID: (Human) 7464
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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