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Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CUL-7; Cullin-7
Gene Aliases: 3M1; CUL7; dJ20C7.5; KIAA0076
UniProt ID: (Human) Q14999
Entrez Gene ID: (Human) 9820
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