Proteintech

Cyclin D1 Polyclonal Antibody

Cyclin D1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

Cyclin D1 Antibody (26939-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using 26939-1-AP (Cyclin D1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Cyclin D1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cyclin D1 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

26939-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 272 publications 272 publications

Immunohistochemistry (IHC)

View 17 publications 17 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

Immunocytochemistry (ICC/IF)

1:50

View 3 publications 3 publications

Flow Cytometry (Flow)

0.4 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Cyclin D1 Fusion Protein Ag25393

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

267 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

Cyclin D1 (PRAD-1, bcl-1) is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. Cyclin D1 is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). In addition, cyclin D1 positively regulates protein phosphorylation, mammary gland epithelial cell proliferation, and fat cell differentiation. In humans, the CCND1 gene encoding cyclin D1 is present on chromosome 11. Cyclin D1 is a cytoplasmic and nuclear protein that is synthesized during G1 phase and assembles with either cyclin-dependent kinase 4 (CDK4) or CDK6 in response to growth factor stimulation. D-type cyclin-CDK complexes act to inactivate the growth-suppressive function of the Rb protein through its phosphorylation, and titrate CDK inhibitors such as p21Cip1 and p27Kip1. Without growth factor-mediated stimulation, Cyclin D1 is unstable, and undergoes ubiquitin-mediated degradation, which is triggered by its phosphorylation. Cyclin D1 destabilization participates in G1/S phase arrest. The Cyclin D1 protein belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. The Cyclin D1 protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. Cyclin D1 has been successfully employed and is a promising tool for further studies in both cell cycle biology and cancer associated abnormalities.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Zhang X,Zou N,Deng W,Song C,Yan K,Shen W,Zhu S

Thu Dec 01 00:00:00 UTC 2022

CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.

Cancer management and research

Zhang W,Wan Y,Zhang Y,Liu Q,Zhu X

Tue Sep 20 00:00:00 UTC 2022

Integrative and Comprehensive Pan-Cancer Analysis of Lymphocyte-Specific Protein Tyrosine Kinase in Human Tumors.

International journal of molecular sciences

Han M,Li Y,Guo Y,Zhu W,Jiang J

Sun Nov 13 00:00:00 UTC 2022

Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.

Frontiers in endocrinology

Deng Y,Li H,Song Y,Cen J,Zhang Y,Sui Y,Cui D,Li TC,Xu Y,Wang CC,Chung PWJ,Tang T

Tue Apr 05 00:00:00 UTC 2022

Blockade of Nuclear β-Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zheng CC,Liao L,Liu YP,Yang YM,He Y,Zhang GG,Li SJ,Liu T,Xu WW,Li B

Thu Dec 01 00:00:00 UTC 2022

Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling.

Journal of nanobiotechnology

Zhao N,Gui X,Fang Q,Zhang R,Zhu W,Zhang H,Li Q,Zhou Y,Zhao J,Cui X,Gao G,Tang H,Shen N,Chen T,Song H,Shen W

Sat Apr 02 00:00:00 UTC 2022

Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.

Oncogene

Hao X,Bu W,Lv G,Xu L,Hou D,Wang J,Liu X,Yang T,Zhang X,Liu Q,Gong Y,Shao C

Sat Jan 01 00:00:00 UTC 2022

Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.

Journal of oncology

Ma L,Shen T,Peng H,Wu J,Wang W,Gao X

Mon May 02 00:00:00 UTC 2022

Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.

Journal of clinical and translational hepatology

Chen CC,Xie XM,Zhao XK,Zuo S,Li HY

Wed Dec 28 00:00:00 UTC 2022

The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.

Experimental cell research

Wei P,Jiang J,Xiao M,Zeng M,Liu X,Zhao B,Chen F

Tue Mar 01 00:00:00 UTC 2022

Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.

Bioengineered

Zhao J,Pan B,Zhou X,Wu C,Hao F,Zhang J,Liu L

Tue Feb 01 00:00:00 UTC 2022

Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.

Toxicology

Pan C,Qin H,Jin H,Chen W,Guo H,Han X

Sat Oct 01 00:00:00 UTC 2022

Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.

Toxicology

Pan C,Qin H,Jin H,Chen W,Guo H,Han X

Sat Oct 01 00:00:00 UTC 2022

Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.

Toxicology

Pan C,Qin H,Jin H,Chen W,Guo H,Han X

Sat Oct 01 00:00:00 UTC 2022

Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies.

Toxicology

Pan C,Qin H,Jin H,Chen W,Guo H,Han X

Sat Oct 01 00:00:00 UTC 2022

Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Varier KM,Dan G,Liu W,Wu G,Xiao C,Lei H,Ling T,Jiang Y,Chen Y,Ben-David Y,Li Y,Zhang N,Gajendran B,Shen X

Thu Dec 01 00:00:00 UTC 2022

A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.

Frontiers in oncology

Rao Z,Li H,Yao W,Wang Q,Ma B,Xue D,Meng X

Tue Aug 16 00:00:00 UTC 2022

Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.

Archives of gerontology and geriatrics

Cabral VLF,Wang F,Peng X,Gao J,Zhou Z,Sun R,Bao J,Wu X

Tue Jul 12 00:00:00 UTC 2022

High expression of eIF4A1 predicts unfavorable prognosis in clear cell renal cell carcinoma.

Molecular and cellular probes

Zhang LL,Chang W,He SB,Zhang B,Ma G,Shang PF,Yue ZJ

Sat Oct 01 00:00:00 UTC 2022

Depletion of B7-H4 from C3H10 T1/2 Mesenchymal Stem Cells Attenuates their Immunomodulatory Therapy in Experimental Autoimmune Encephalomyelitis Mice.

Neurotoxicity research

Li H,Sun S,Yin Z,Cao S,Ji X,Duan X,Gao H,Wang M,Fang Q,Dong W,Zhang X,Gu Y,Xue Q

Wed Jun 01 00:00:00 UTC 2022

G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway.

Anti-cancer drugs

Yuan Z,Ren R,Xu Z

Tue Nov 01 00:00:00 UTC 2022

Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.

European journal of medicinal chemistry

Liang JJ,Yu WL,Yang L,Qin KM,Yin YP,Li D,Ni YH,Yan JJ,Zhong YX,Deng ZX,Hong K

Sun Jun 05 00:00:00 UTC 2022

FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value.

Experimental cell research

Zheng C,Ren Z,Chen H,Yuan X,Suye S,Yin H,Zhou Z,Fu C

Thu Dec 15 00:00:00 UTC 2022

Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.

Frontiers in oncology

Wang H,Zhao S,Liu Y,Sun F,Huang X,Wu T

Sat Jul 16 00:00:00 UTC 2022

Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.

Frontiers in oncology

Wang H,Zhao S,Liu Y,Sun F,Huang X,Wu T

Sat Jul 16 00:00:00 UTC 2022

Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Li R,Li H,Lan J,Yang D,Lin X,Xu H,Han B,Yang M,Su B,Liu F,Jiang W

Wed Jun 01 00:00:00 UTC 2022

MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.

Environmental toxicology

Jin X,Yu W,Ye P

Fri Apr 01 00:00:00 UTC 2022

Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism.

Cell death & disease

Li P,Lin Q,Sun S,Yang N,Xia Y,Cao S,Zhang W,Li Q,Guo H,Zhu M,Wang Y,Zheng Z,Li S

Wed Sep 21 00:00:00 UTC 2022

The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.

Cancer gene therapy

Wang F,Luo Y,Zhang L,Younis M,Yuan L

Tue Mar 01 00:00:00 UTC 2022

Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway.

Cancer chemotherapy and pharmacology

Xu P,Wang H,Pan H,Chen J,Deng C

Tue Feb 01 00:00:00 UTC 2022

Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia.

Journal of nanobiotechnology

Lin L,Song C,Wei Z,Zou H,Han S,Cao Z,Zhang X,Zhang G,Ran J,Cai Y,Han W

Fri Mar 04 00:00:00 UTC 2022

Lactation Activity and Mechanism of Milk-Protein Synthesis by Peptides from Oyster Hydrolysates.

Nutrients

Chen S,Qin X,Zhang C,Cao W,Zheng H,Lin H

Sun Apr 24 00:00:00 UTC 2022

MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.

Oncology letters

Gong J,Shen Y,Jiang F,Wang Y,Chu L,Sun J,Shen P,Chen M

Sun May 01 00:00:00 UTC 2022

Interplay between liver circadian rhythm and regeneration after PHx.

Genomics

Wei S,Zheng Q,Pan Y,Xu Y,Tang J,Cai X

Sat Jan 01 00:00:00 UTC 2022

Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.

Materials today. Bio

Fu Z,Du H,Meng S,Yao M,Zhao P,Li X,Zheng X,Yuan Z,Yang H,Cai K,Dai L

Thu Dec 01 00:00:00 UTC 2022

Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury.

Neural regeneration research

Tang W,Guo ZD,Chai WN,Du DL,Yang XM,Cao L,Chen H,Zhou C,Cheng CJ,Sun XC,Huang ZJ,Zhong JJ

Tue Mar 01 00:00:00 UTC 2022

Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.

Cellular signalling

Hao J,Xi Y,Jiao L,Wen X,Wu R,Chang G,Sun F,Wei C,Li H

Thu Dec 01 00:00:00 UTC 2022

Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.

International journal of biological sciences

Gou W,Luo N,Yu B,Wu H,Wu S,Tian C,Guo J,Ning H,Bi C,Wei H,Hou W,Li Y

Thu Apr 14 00:00:00 UTC 2022

Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.

Oxidative medicine and cellular longevity

Shi L,Li Y,Shi M,Li X,Li G,Cen J,Liu D,Wei C,Lin Y

Wed Sep 07 00:00:00 UTC 2022

lncRNA NEAT1-let 7b-P21 axis mediates the proliferation of neural stem cells cultured in vitro promoted by radial extracorporeal shock wave.

Regenerative therapy

Han K,Kang N,Yu X,Lu J,Ma Y

Thu Dec 01 00:00:00 UTC 2022

MRC2 Promotes Proliferation and Inhibits Apoptosis of Diabetic Nephropathy.

Analytical cellular pathology (Amsterdam)

Li L,Chen X,Zhang H,Wang M,Lu W

Mon Dec 13 00:00:00 UTC 2021

Exogenous H₂ S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.

Journal of cellular and molecular medicine

Zhang L,Jiang X,Liu N,Li M,Kang J,Chen L,Tang J,Dong S,Lu F,Zhang W

Wed Sep 01 00:00:00 UTC 2021

Tacrolimus inhibits oral carcinogenesis through cell cycle control.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Li Y,Wang Y,Li J,Ling Z,Chen W,Zhang L,Hu Q,Wu T,Cheng B,Wang Y,Xia J

Thu Jul 01 00:00:00 UTC 2021

LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.

Cell death & disease

Tao Y,Zhang J,Chen L,Liu X,Yao M,Zhang H

Tue May 18 00:00:00 UTC 2021

Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway.

Frontiers in oncology

Cheng Y,Wang G,Zhao L,Dai S,Han J,Hu X,Zhou C,Wang F,Ma H,Li B,Meng Z

Wed Dec 15 00:00:00 UTC 2021

Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.

European journal of pharmacology

Meng H,Shen M,Li J,Zhang R,Li X,Zhao L,Huang G,Liu J

Sun Sep 05 00:00:00 UTC 2021

Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.

Biomedical and environmental sciences : BES

Li MJ,Xiong D,Huang H,Wen ZY

Sat Feb 20 00:00:00 UTC 2021

Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.

Frontiers in pharmacology

Yang M,Li WY,Xie J,Wang ZL,Wen YL,Zhao CC,Tao L,Li LF,Tian Y,Sheng J

Sat May 08 00:00:00 UTC 2021

A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.

Journal of materials chemistry. B

Long Y,Wang Z,Fan J,Yuan L,Tong C,Zhao Y,Liu B

Wed May 12 00:00:00 UTC 2021

Identification and Validation of HOTAIRM1 as a Novel Biomarker for Oral Squamous Cell Carcinoma.

Frontiers in bioengineering and biotechnology

Yu Y,Niu J,Zhang X,Wang X,Song H,Liu Y,Jiao X,Chen F

Sat Jan 29 00:00:00 UTC 2022

Network pharmacology-guided mechanism study uncovers inhibitory effect of Mahuang Decoction on lung cancer growth by impeding Akt/ERK signaling pathways.

American journal of translational research

Pan Y,Chen Y,Wu C,Ai J,Wang Y,Jia J,Liu L

Sun May 23 00:00:00 UTC 2021

Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.

Oxidative medicine and cellular longevity

Yuan C,Bai R,Gao Y,Jiang X,Li S,Sun W,Li Y,Huang Z,Gong Y,Xie C

Mon Feb 28 00:00:00 UTC 2022

HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.

Cancer medicine

Sun W,Li S,Tang G,Sun S,Luo Y,Bai R,Han L,Jiang X,Gao Y,Huang Z,Zhang J,Gong Y,Xie C

Sun Aug 01 00:00:00 UTC 2021

Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.

European journal of medicinal chemistry

Wang S,Zhang RH,Zhang H,Wang YC,Yang D,Zhao YL,Yan GY,Xu GB,Guan HY,Zhou YH,Cui DB,Liu T,Li YJ,Liao SG,Zhou M

Fri Oct 15 00:00:00 UTC 2021

Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.

Journal of pineal research

Cui L,Zhao X,Jin Z,Wang H,Yang SF,Hu S

Wed Dec 01 00:00:00 UTC 2021

PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.

Biochemical and biophysical research communications

Ma S,Quan P,Yu C,Fan X,Yang S,Jia W,Zhang L,Wang F,Liu F,Yang L,Qin W,Yang X

Fri Sep 24 00:00:00 UTC 2021

CDCA7 Facilitates Tumor Progression by Directly Regulating CCNA2 Expression in Esophageal Squamous Cell Carcinoma.

Frontiers in oncology

Li H,Weng Y,Wang S,Wang F,Wang Y,Kong P,Zhang L,Cheng C,Cui H,Xu E,Wei S,Guo D,Chen F,Bi Y,Meng Y,Cheng X,Cui Y

Thu Apr 28 00:00:00 UTC 2022

Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.

Fitoterapia

Jin J,Zhou M,Wang X,Liu M,Huang H,Yan F,Yu Z,Shu X,Huo X,Feng L,Zhang B,Huang S,Deng S,Wang C,Ma X

Fri Jan 01 00:00:00 UTC 2021

Apatinib regulates the growth of gastric cancer cells by modulating apoptosis and autophagy.

Naunyn-Schmiedeberg's archives of pharmacology

Liu X,Zheng Q,Yu Q,Hu Y,Cheng Y,Shao Z,Chen L,Ding W,Gao D

Sat May 01 00:00:00 UTC 2021

Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer.

OncoTargets and therapy

Wang G,Wang X,Han M,Wang X

Wed Apr 20 00:00:00 UTC 2022

Puromycin-sensitive aminopeptidase is required for C2C12 myoblast proliferation and differentiation.

Journal of cellular physiology

Osana S,Kitajima Y,Suzuki N,Nunomiya A,Takada H,Kubota T,Murayama K,Nagatomi R

Thu Jul 01 00:00:00 UTC 2021

Downregulation of m⁶A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.

International journal of biological sciences

Wang J,Tan L,Jia B,Yu X,Yao R,OUYang N,Yu X,Cao X,Tong J,Chen T,Chen R,Li J

Wed Mar 16 00:00:00 UTC 2022

Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition.

Technology in cancer research & treatment

Su Y,Zhou L,Yu Q,Lu J,Liu W

Wed Nov 10 00:00:00 UTC 2021

Paired-like homeodomain transcription factor 2 affects endometrial cell function and embryo implantation through the Wnt/β-catenin pathway.

Cell biology international

Zhang H,Qi J,Guo J,Wang Y,Guan Y,Fan J,Sui L,Xu Y,Kong L,Yan B,Kong Y

Wed Sep 01 00:00:00 UTC 2021

Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.

Frontiers in oncology

Shi S,Li C,Zhang Y,Deng C,Liu W,Du J,Li Q,Ji Y,Guo L,Liu L,Hu H,Liu Y,Cui H

Sat Nov 11 00:00:00 UTC 2023

Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.

Journal of experimental & clinical cancer research : CR

Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C

Tue Aug 24 00:00:00 UTC 2021

Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.

Journal of experimental & clinical cancer research : CR

Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C

Tue Aug 24 00:00:00 UTC 2021

miRNA‑7515 suppresses pancreatic cancer cell proliferation, migration and invasion via downregulating IGF‑1 expression.

Oncology reports

Lei S,Zeng Z,He Z,Cao W

Wed Sep 01 00:00:00 UTC 2021

M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.

Journal of Crohn's & colitis

Deng F,Yan J,Lu J,Luo M,Xia P,Liu S,Wang X,Zhi F,Liu D

Tue Apr 06 00:00:00 UTC 2021

Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway.

Journal of Cancer

Zhang J,Li P,Li T,Zhou Z,Wu H,Zhang L

Sat Feb 19 00:00:00 UTC 2022

ACTL6A Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells and Correlates with Poor Clinical Outcomes.

OncoTargets and therapy

Li RZ,Li YY,Qin H,Li SS

Wed Apr 20 00:00:00 UTC 2022

miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.

Cellular signalling

Xiong X,Xu W,Gong J,Wang L,Dai M,Chen G,Yuan L

Fri Jan 01 00:00:00 UTC 2021

CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma.

Frontiers in molecular biosciences

Feng F,Zhao Z,Zhou Y,Cheng Y,Wu X,Heng X

Tue Aug 24 00:00:00 UTC 2021

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.

Cell death discovery

Ren M,Xu H,Xia H,Tang Q,Bi F

Sat May 29 00:00:00 UTC 2021

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.

Cell death discovery

Ren M,Xu H,Xia H,Tang Q,Bi F

Sat May 29 00:00:00 UTC 2021

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.

Cell death discovery

Ren M,Xu H,Xia H,Tang Q,Bi F

Sat May 29 00:00:00 UTC 2021

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.

Cell death discovery

Ren M,Xu H,Xia H,Tang Q,Bi F

Sat May 29 00:00:00 UTC 2021

Myricetin Induces Autophagy and Cell Cycle Arrest of HCC by Inhibiting MARCH1-Regulated Stat3 and p38 MAPK Signaling Pathways.

Frontiers in pharmacology

Yang W,Su J,Li M,Li T,Wang X,Zhao M,Hu X

Fri Nov 05 00:00:00 UTC 2021

A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.

Cell death discovery

Li P,Cao S,Huang Y,Zhang Y,Liu J,Cai X,Zhou L,Li J,Jiang Z,Ding L,Zheng Z,Li S,Ye Q

Thu Jul 29 00:00:00 UTC 2021

MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.

Bioengineered

Xu W,Ye L,Wu H

Wed Dec 01 00:00:00 UTC 2021

Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.

Journal of hepatocellular carcinoma

Xie X,Chen C,Feng S,Zuo S,Zhao X,Li H

Fri Apr 29 00:00:00 UTC 2022

Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.

Frontiers in oncology

Zhang Y,Wang D,Lv B,Hou X,Liu Q,Liao C,Xu R,Zhang Y,Xu F,Zhang P

Fri Aug 27 00:00:00 UTC 2021

LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.

Carcinogenesis

Huang Y,Lin Y,Song X,Wu D

Fri May 28 00:00:00 UTC 2021

Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro.

International journal of biological sciences

Bai M,Cui M,Li M,Yao X,Wu Y,Zheng L,Sun L,Song Q,Wang S,Liu L,Yu C,Huang Y

Tue Feb 22 00:00:00 UTC 2022

Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.

OncoTargets and therapy

Chen Z,Zhang Y,Wu X,Zhang J,Xu W,Shen C,Zheng B

Fri Apr 22 00:00:00 UTC 2022

MiR-3663-3p Inhibits the Progression of Gastric Cancer Through the CCND1 Pathway.

Anticancer research

Takao K,Konishi H,Matsubara D,Shoda K,Arita T,Shimizu H,Komatsu S,Shiozaki A,Yamamoto Y,Kubota T,Fujiwara H,Okamoto K,Otsuji E

Sat May 01 00:00:00 UTC 2021

Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.

Frontiers in immunology

Huang Y,Huang S,Ma L,Wang Y,Wang X,Xiao L,Qin W,Li L,Yuan X

Mon Feb 07 00:00:00 UTC 2022

Transmembrane Protein Ttyh1 Maintains the Quiescence of Neural Stem Cells Through Ca²⁺/NFATc3 Signaling.

Frontiers in cell and developmental biology

Cao Y,Wu HN,Cao XL,Yue KY,Han WJ,Cao ZP,Zhang YF,Gao XY,Luo C,Jiang XF,Han H,Zheng MH

Thu Apr 04 00:00:00 UTC 2024

ActivinA activates Notch1-Shh signaling to regulate proliferation in C2C12 skeletal muscle cells.

Molecular and cellular endocrinology

Ma L,Li C,Lian S,Xu B,Yuan J,Lu J,Yang H,Guo J,Ji H

Fri Jan 01 00:00:00 UTC 2021

Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway.

Stem cell research & therapy

Lin Z,Zhao C,Lei Z,Zhang Y,Huang R,Lin B,Dong Y,Zhang H,Li J,Li X

Thu Jun 10 00:00:00 UTC 2021

Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na_V 1.5-mediated EMT and FAK/Paxillin signaling pathway.

Cancer medicine

Liu C,Yu M,Li Y,Wang H,Xu C,Zhang X,Li M,Guo H,Ma D,Guo X

Fri Jan 01 00:00:00 UTC 2021

Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis.

Veterinary sciences

Gao X,Yao X,Li X,Liang Y,Liu Z,Wang Z,Li K,Li Y,Zhang G,Wang F

Thu Dec 09 00:00:00 UTC 2021

In Hepatocellular Carcinoma, miRNA-296-3p Targets MSL2 and Suppresses Cell Proliferation and Invasion.

Journal of oncology

Li X,An M,Gao Z

Wed Dec 15 00:00:00 UTC 2021

NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.

International journal of biological sciences

Bai R,Yuan C,Sun W,Zhang J,Luo Y,Gao Y,Li Y,Gong Y,Xie C

Fri Mar 25 00:00:00 UTC 2022

DNA methylation mediated RSPO2 to promote follicular development in mammals.

Cell death & disease

Zhou X,He Y,Li N,Bai G,Pan X,Zhang Z,Zhang H,Li J,Yuan X

Sat Jun 26 00:00:00 UTC 2021

Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.

Frontiers in oncology

Zhu X,Li R,Wang C,Zhou S,Fan Y,Ma S,Gao D,Gai N,Yang J

Tue Aug 03 00:00:00 UTC 2021

Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.

Frontiers in molecular biosciences

Yang W,Feng Q,Li M,Su J,Wang P,Wang X,Yin Y,Wang X,Zhao M

Tue Jun 29 00:00:00 UTC 2021

Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G₀/G₁ Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation.

Oxidative medicine and cellular longevity

Zhang Y,Chen G,Zhuang X,Guo M

Fri Mar 04 00:00:00 UTC 2022

ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway.

Oncology letters

Yu S,Wang S,Sun X,Wu Y,Zhao J,Liu J,Yang D,Jiang Y

Fri Oct 01 00:00:00 UTC 2021

Apatinib suppresses lung cancer stem-like cells by complex interplay between β-catenin signaling and mitochondrial ROS accumulation.

Cell death discovery

Zhu J,Li X,Liang C,Zhou X,Ge M,Chen Y,Jin J,Yin J,Xu H,Xie C,Zhong C

Wed May 12 00:00:00 UTC 2021

eIF6 promotes the malignant progression of human hepatocellular carcinoma via the mTOR signaling pathway.

Journal of translational medicine

Sun L,Liu S,Wang X,Zheng X,Chen Y,Shen H

Thu May 20 00:00:00 UTC 2021

Dimethyl fumarate inhibits antibody-induced platelet destruction in immune thrombocytopenia mouse.

Thrombosis journal

Tong H,Ding Y,Gui X,Sun Z,Wang G,Zhang S,Xu Z,Wang X,Xu X,Ju W,Li Y,Li Z,Zeng L,Xu K,Qiao J

Sat Aug 28 00:00:00 UTC 2021

TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.

Canadian journal of physiology and pharmacology

Li M,Zhu H,Hu X,Gao F,Hu X,Cui Y,Wei X,Xie C,Lv G,Zhao Y,Gao Y

Sat May 01 00:00:00 UTC 2021

ESM1 promotes triple-negative breast cancer cell proliferation through activating AKT/NF-κB/Cyclin D1 pathway.

Annals of translational medicine

Liu W,Yang Y,He B,Ma F,Sun F,Guo M,Zhang M,Dong Z

Thu Apr 01 00:00:00 UTC 2021

ZNF750 exerted its Antitumor Action in Oral Squamous Cell Carcinoma by regulating E2F2.

Journal of Cancer

Yang HL,Xu C,Yang YK,Tang WQ,Hong M,Pan L,Chen HY

Sat Feb 19 00:00:00 UTC 2022

Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.

Frontiers in pharmacology

Xie B,Zeng Z,Liao S,Zhou C,Wu L,Xu D

Sat Oct 23 00:00:00 UTC 2021

Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.

Frontiers in veterinary science

Ou G,Jiang X,Gao A,Li X,Lin Z,Pei S

Wed Feb 23 00:00:00 UTC 2022

ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.

Journal of experimental & clinical cancer research : CR

Zhang M,Wang L,Yue Y,Zhang L,Liu T,Jing M,Liang X,Ma M,Xu S,Wang K,Wang X,Fan J

Thu Feb 11 00:00:00 UTC 2021

Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.

Cancer science

Du W,Gao A,Herman JG,Wang L,Zhang L,Jiao S,Guo M

Thu Jul 01 00:00:00 UTC 2021

LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.

Cellular and molecular neurobiology

He X,Sheng J,Yu W,Wang K,Zhu S,Liu Q

Sun Aug 01 00:00:00 UTC 2021

CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.

Oncogenesis

Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L

Fri Dec 03 00:00:00 UTC 2021

Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.

Biochemical and biophysical research communications

Li Q,Luan Q,Zhu H,Zhao Y,Ji J,Wu F,Yan J

Fri Apr 30 00:00:00 UTC 2021

The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.

Frontiers in oncology

Ni K,Huang Z,Zhu Y,Xue D,Jin Q,Zhang C,Gu C

Sun Apr 24 00:00:00 UTC 2022

Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.

Biochemical and biophysical research communications

Wang Q,Dong Z,Su J,Huang J,Xiao P,Tian L,Chen Y,Ma L,Chen X

Fri Apr 16 00:00:00 UTC 2021

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.

Bioengineered

Zhang S,Wang J,Chen T,Wang J,Wang Y,Yu Z,Zhao K,Zheng K,Chen Y,Wang Z,Li B,Wang C,Huang W,Fu Z,Chen J

Wed Dec 01 00:00:00 UTC 2021

Role of Glycated High Mobility Group Box-1 in Gastric Cancer.

International journal of molecular sciences

Kishi S,Nishiguchi Y,Honoki K,Mori S,Fujiwara-Tani R,Sasaki T,Fujii K,Kawahara I,Goto K,Nakashima C,Kido A,Tanaka Y,Luo Y,Kuniyasu H

Thu May 13 00:00:00 UTC 2021

AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang Z,Wu H,Huang S,Chen L,Chen X,Zhang W,Liao L,Zhang X

Tue Jun 01 00:00:00 UTC 2021

F4/80⁺ Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway.

Molecules (Basel, Switzerland)

Lu Q,Shen H,Yu H,Fu J,Dong H,Chen Y,Wang H

Tue Apr 13 00:00:00 UTC 2021

Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.

Frontiers in cell and developmental biology

Cao W,Li Y,Sun H,Yang C,Zhu J,Xie C,Li X,Wu J,Geng S,Wang L,Sun L,Geng G,Han H,Zhong C

Fri Aug 06 00:00:00 UTC 2021

Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells.

Journal of agricultural and food chemistry

Wu H,Cui M,Li C,Li H,Dai Y,Cui K,Li Z

Wed Mar 17 00:00:00 UTC 2021

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.

Journal of ethnopharmacology

Wang Y,Chu F,Lin J,Li Y,Johnson N,Zhang J,Gai C,Su Z,Cheng H,Wang L,Ding X

Thu Oct 28 00:00:00 UTC 2021

MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1).

Bioengineered

Song GL,Xiao M,Wan XY,Deng J,Ling JD,Tian YG,Li M,Yin J,Zheng RY,Tang Y,Liu GY

Wed Dec 01 00:00:00 UTC 2021

Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.

Clinical science (London, England : 1979)

Chen Y,Xu T,Li M,Li C,Ma Y,Chen G,Sun Y,Zheng H,Wu G,Liao W,Liao Y,Chen Y,Bin J

Fri Mar 26 00:00:00 UTC 2021

CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.

Cell proliferation

Ying Y,Li J,Xie H,Yan H,Jin K,He L,Ma X,Wu J,Xu X,Fang J,Wang X,Zheng X,Liu B,Xie L

Sat Feb 01 00:00:00 UTC 2020

CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.

Cell proliferation

Ying Y,Li J,Xie H,Yan H,Jin K,He L,Ma X,Wu J,Xu X,Fang J,Wang X,Zheng X,Liu B,Xie L

Sat Feb 01 00:00:00 UTC 2020

CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.

Cell proliferation

Ying Y,Li J,Xie H,Yan H,Jin K,He L,Ma X,Wu J,Xu X,Fang J,Wang X,Zheng X,Liu B,Xie L

Sat Feb 01 00:00:00 UTC 2020

CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.

Cell proliferation

Ying Y,Li J,Xie H,Yan H,Jin K,He L,Ma X,Wu J,Xu X,Fang J,Wang X,Zheng X,Liu B,Xie L

Sat Feb 01 00:00:00 UTC 2020

Silencing of ELK3 Induces S-M Phase Arrest and Apoptosis and Upregulates SERPINE1 Expression Reducing Migration in Prostate Cancer Cells.

BioMed research international

Mao Y,Li W,Hua B,Gu X,Pan W,Chen Q,Xu B,Wang Z,Lu C

Thu Nov 19 00:00:00 UTC 2020

Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.

Frontiers in medicine

Zeng Y,Zou M,Liu Y,Que K,Wang Y,Liu C,Gong J,You Y

Thu Dec 17 00:00:00 UTC 2020

Effect of KIF22 on promoting proliferation and migration of gastric cancer cells via MAPK-ERK pathways.

Chinese medical journal

Yu ZY,Jiang XY,Zhao RR,Qin JJ,Luo CJ,Ren YX,Ren W,Ma ZJ,Jiao ZY

Mon Apr 20 00:00:00 UTC 2020

Helium/Argon-Generated Cold Atmospheric Plasma Facilitates Cutaneous Wound Healing.

Frontiers in bioengineering and biotechnology

Lou BS,Hsieh JH,Chen CM,Hou CW,Wu HY,Chou PY,Lai CH,Lee JW

Mon Sep 28 00:00:00 UTC 2020

RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.

Journal of experimental & clinical cancer research : CR

Yang Z,Wang T,Wu D,Min Z,Tan J,Yu B

Tue Sep 29 00:00:00 UTC 2020

Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.

Cancer management and research

Guo W,Zhao L,Wei G,Liu P,Zhang Y,Fu L

Sat Apr 16 00:00:00 UTC 2022

GRHL2 Upregulation Predicts a Poor Prognosis and Promotes the Resistance of Serous Ovarian Cancer to Cisplatin.

OncoTargets and therapy

Nie Y,Ding Y,Yang M

Fri Apr 15 00:00:00 UTC 2022

lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC.

Molecular therapy. Nucleic acids

Zhou L,Liu R,Liang X,Zhang S,Bi W,Yang M,He Y,Jin J,Li S,Yang X,Fu J,Zhang P

Fri Dec 04 00:00:00 UTC 2020

CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.

Aging

Cui Y,Song Y,Yan S,Cao M,Huang J,Jia D,Liu Y,Zhang S,Fan W,Cai L,Li C,Xing Y

Sun Oct 25 00:00:00 UTC 2020

CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.

Aging

Cui Y,Song Y,Yan S,Cao M,Huang J,Jia D,Liu Y,Zhang S,Fan W,Cai L,Li C,Xing Y

Sun Oct 25 00:00:00 UTC 2020

Magnetic targeting enhances the cutaneous wound healing effects of human mesenchymal stem cell-derived iron oxide exosomes.

Journal of nanobiotechnology

Li X,Wang Y,Shi L,Li B,Li J,Wei Z,Lv H,Wu L,Zhang H,Yang B,Xu X,Jiang J

Fri Aug 14 00:00:00 UTC 2020

Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration.

Chinese medicine

Liu H,Liao W,Fan L,Zheng Z,Liu D,Zhang QW,Yang A,Liu F

Tue Apr 12 00:00:00 UTC 2022

Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.

Chemistry & biodiversity

Wei J,Yu W,Hao R,Fan J,Gao J

Sun Nov 01 00:00:00 UTC 2020

LncRNA TROJAN promotes proliferation and resistance to CDK4/6 inhibitor via CDK2 transcriptional activation in ER+ breast cancer.

Molecular cancer

Jin X,Ge LP,Li DQ,Shao ZM,Di GH,Xu XE,Jiang YZ

Mon May 11 00:00:00 UTC 2020

BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.

Life sciences

Zeng ZM,Du HY,Xiong L,Zeng XL,Zhang P,Cai J,Huang L,Liu AW

Sun Mar 01 00:00:00 UTC 2020

UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.

Oxidative medicine and cellular longevity

Kuang M,Yang M,Li L,Li C,Wang G

Wed May 05 00:00:00 UTC 2021

Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells.

Bioscience, biotechnology, and biochemistry

Zhang L,Wang Z,Kong D,Zhao X,Chen X,Chai W

Sat Aug 01 00:00:00 UTC 2020

Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment the HMGB1/RAGE/IL-8 axis.

Cancer biology & medicine

Zha C,Meng X,Li L,Mi S,Qian D,Li Z,Wu P,Hu S,Zhao S,Cai J,Liu Y

Sat Feb 15 00:00:00 UTC 2020

HOTAIR-EZH2 inhibitor AC1Q3QWB upregulates CWF19L1 and enhances cell cycle inhibition of CDK4/6 inhibitor palbociclib in glioma.

Clinical and translational medicine

Shi J,Lv S,Wu M,Wang X,Deng Y,Li Y,Li K,Zhao H,Zhu X,Ye M

Wed Jan 01 00:00:00 UTC 2020

METTL3/YTHDF2 m⁶ A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.

Journal of cellular and molecular medicine

Xie H,Li J,Ying Y,Yan H,Jin K,Ma X,He L,Xu X,Liu B,Wang X,Zheng X,Xie L

Wed Apr 01 00:00:00 UTC 2020

Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.

Journal of food science

Wang D,Zhu X,Tang X,Li H,Yizhen X,Chen D

Mon Jun 01 00:00:00 UTC 2020

IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.

Journal of cellular physiology

Wang Z,Qi Y,Wang R,Wu W,Li Z,Wang M,Liu R,Zhang C,Li W,Wang S

Tue Dec 01 00:00:00 UTC 2020

Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.

Molecular therapy. Nucleic acids

Guo X,Dai X,Liu J,Cheng A,Qin C,Wang Z

Fri Sep 04 00:00:00 UTC 2020

Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancer.

Bioscience reports

Zhou H,Xiong Y,Zhang G,Liu Z,Li L,Hou S,Zhou T

Fri Jul 31 00:00:00 UTC 2020

Long Non-Coding RNA THOR Enhances the Stem Cell-Like Traits of Triple-Negative Breast Cancer Cells Through Activating β-Catenin Signaling.

Medical science monitor : international medical journal of experimental and clinical research

Wang B,Ye Q,Zou C

Tue Jul 14 00:00:00 UTC 2020

Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer.

The international journal of biochemistry & cell biology

Luo F,Zhao Y,Liu J

Mon Jun 01 00:00:00 UTC 2020

A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma.

OncoTargets and therapy

Sun Y,Niu X,Wang G,Qiao X,Chen L,Zhong M

Wed Apr 13 00:00:00 UTC 2022

The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.

Chemical & pharmaceutical bulletin

Feng B,Zhao C,Li J,Yu J,Zhang Y,Zhang X,Tian T,Zhao L

Fri Apr 30 00:00:00 UTC 2021

circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.

Journal of experimental & clinical cancer research : CR

Yu C,Cheng Z,Cui S,Mao X,Li B,Fu Y,Wang H,Jin H,Ye Q,Zhao X,Jiang L,Qin W

Mon Mar 30 00:00:00 UTC 2020

siRNA knockdown of alanine aminopeptidase impairs myoblast proliferation and differentiation.

Experimental cell research

Osana S,Kitajima Y,Suzuki N,Xu Y,Murayama K,Nagatomi R

Tue Dec 01 00:00:00 UTC 2020

Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.

Technology in cancer research & treatment

Zhu Y,Shi F,Wang M,Ding J

Fri Nov 20 00:00:00 UTC 2020

A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer.

Frontiers in pharmacology

Pan B,Wang Y,Wu C,Jia J,Huang C,Fang S,Liu L

Sat Mar 30 00:00:00 UTC 2024

Mechanism of inhibiting proliferation of hepatocellular carcinoma Hepa1-6 cells by embryonic stem cell-conditioned medium.

Experimental and therapeutic medicine

Li L,Zheng Y,Zheng Q,Jiang J

Wed Apr 01 00:00:00 UTC 2020

Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.

The Kaohsiung journal of medical sciences

Wang LJ,Cai HQ

Thu Oct 01 00:00:00 UTC 2020

ERO1L promotes NSCLC development by modulating cell cycle-related molecules.

Cell biology international

Shi X,Wu J,Liu Y,Jiang Y,Zhi C,Li J

Tue Dec 01 00:00:00 UTC 2020

miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.

Cancer cell international

An Y,Zhang J,Cheng X,Li B,Tian Y,Zhang X,Zhao F

Fri Apr 15 00:00:00 UTC 2022

Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.

Neuroscience

Wu J,He J,Tian X,Li H,Wen Y,Shao Q,Cheng C,Wang G,Sun X

Sat Aug 01 00:00:00 UTC 2020

Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.

Cancer letters

Yang Y,Wei Q,Tang Y,Luo Q,Zhao H,He M,Wang H,Zeng Q,Lu W,Xu J,Liu T,Yi P

Fri Apr 10 00:00:00 UTC 2020

CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma.

Frontiers in oncology

Song Y,Song W,Li Z,Song W,Wen Y,Li J,Xia Q,Zhang M

Mon Feb 15 00:00:00 UTC 2021

Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.

Journal of cellular biochemistry

Zheng Y,Nie P,Xu S

Mon Jun 01 00:00:00 UTC 2020

Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.

Endocrine pathology

Gucer H,Caliskan S,Kefeli M,Mete O

Sun Mar 01 00:00:00 UTC 2020

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.

BioMed research international

Lin W,Tong C,Zhang W,Cen W,Wang Y,Li J,Zhu Z,Yu J,Lu B

Thu Apr 29 00:00:00 UTC 2021

Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma.

BioMed research international

Meng X,Wang L,Zhu B,Zhang J,Guo S,Li Q,Zhang T,Zheng Z,Wu G,Zhao Y

Mon Mar 08 00:00:00 UTC 2021

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression.

Aging cell

Dang Y,An Y,He J,Huang B,Zhu J,Gao M,Zhang S,Wang X,Yang B,Xie Z

Wed Jan 01 00:00:00 UTC 2020

Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.

Environmental toxicology

Zhao Q,Sun P,Qin S,Liu J

Tue Dec 01 00:00:00 UTC 2020

Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.

Journal of cellular and molecular medicine

Zhang WL,Wang SS,Jiang YP,Liu Y,Yu XH,Wu JB,Wang K,Pang X,Liao P,Liang XH,Tang YL

Thu Oct 01 00:00:00 UTC 2020

Fatty acid synthase contributes to epithelial-mesenchymal transition and invasion of salivary adenoid cystic carcinoma through PRRX1/Wnt/β-catenin pathway.

Journal of cellular and molecular medicine

Zhang WL,Wang SS,Jiang YP,Liu Y,Yu XH,Wu JB,Wang K,Pang X,Liao P,Liang XH,Tang YL

Thu Oct 01 00:00:00 UTC 2020

NCAPG Induces Cell Proliferation in Cardia Adenocarcinoma via PI3K/AKT Signaling Pathway.

OncoTargets and therapy

Zhang X,Wang H,Han Y,Zhu M,Song Z,Zhan D,Jia J

Mon Apr 18 00:00:00 UTC 2022

Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.

Molecular therapy. Nucleic acids

Wang Z,Zhao Y,Zhao H,Zhou J,Feng D,Tang F,Li Y,Lv L,Chen Z,Ma X,Tian X,Yao J

Fri Sep 04 00:00:00 UTC 2020

MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B.

International journal of molecular medicine

Chen T,Lei S,Zeng Z,Pan S,Zhang J,Xue Y,Sun Y,Lan J,Xu S,Mao D,Guo B

Sun Mar 01 00:00:00 UTC 2020

Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.

Life sciences

Chen Y,Niu J,Li L,Li Z,Jiang J,Zhu M,Dong T,Zhang J,Shi C,Xu P,Lu Y,Jiang Y,Liu P,Chen W

Thu Oct 01 00:00:00 UTC 2020

Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.

Life sciences

Chen Y,Niu J,Li L,Li Z,Jiang J,Zhu M,Dong T,Zhang J,Shi C,Xu P,Lu Y,Jiang Y,Liu P,Chen W

Thu Oct 01 00:00:00 UTC 2020

PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.

EBioMedicine

Li D,Lin C,Li N,Du Y,Yang C,Bai Y,Feng Z,Su C,Wu R,Song S,Yan P,Chen M,Jain A,Huang L,Zhang Y,Li X

Mon Jul 01 00:00:00 UTC 2019

Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.

Toxicology mechanisms and methods

Lanxiang W,Bin W,Ge X,Yutang H,Chunjie W,Honghao Z

Fri Nov 01 00:00:00 UTC 2019

Glycogen phosphorylase B promotes ovarian cancer progression via Wnt/β-catenin signaling and is regulated by miR-133a-3p.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhou Y,Jin Z,Wang C

Sun Dec 01 00:00:00 UTC 2019

UHRF1 Promotes Proliferation of Human Adipose-Derived Stem Cells and Suppresses Adipogenesis via Inhibiting Peroxisome Proliferator-Activated Receptor γ.

BioMed research international

Chen K,Guo Z,Luo Y,Yuan J,Mo Z

Wed Jan 15 00:00:00 UTC 2020

Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway.

Cancer management and research

Guo L,Yang T

Tue Aug 09 00:00:00 UTC 2022

MiR-26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β-catenin signaling.

Cancer medicine

Hu X,Wang R,Ren Z,Liu X,Gu J,Cui G,Li Q

Sun Dec 01 00:00:00 UTC 2019

Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis.

Cell cycle (Georgetown, Tex.)

Zhang Y,Xu L,Wang P,Jian H,Shi X,Jia M,Mo L,Hu Z,Li H,Li J

Thu Aug 01 00:00:00 UTC 2019

Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.

Molecular and cellular biochemistry

Cui Y,Zhang L,Wang W,Ma S,Liu H,Zang X,Zhang Y,Guan F

Tue Oct 01 00:00:00 UTC 2019

Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer.

Medical science monitor : international medical journal of experimental and clinical research

Li Y,Zu X,Hu X,Wang L,He W

Mon Nov 25 00:00:00 UTC 2019

Upregulation of ERp57 promotes clear cell renal cell carcinoma progression by initiating a STAT3/ILF3 feedback loop.

Journal of experimental & clinical cancer research : CR

Liu Y,Wang JX,Nie ZY,Wen Y,Jia XJ,Zhang LN,Duan HJ,Shi YH

Wed Oct 30 00:00:00 UTC 2019

miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.

Gene

Wang S,Wu Y,Xu Y,Tang X

Tue Aug 20 00:00:00 UTC 2019

A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.

Toxicology and applied pharmacology

Shen J,Wang J,Du J,Wang L,Zhou X,Chang X,Li Z,Zhai X,Zuo D,Wu Y

Fri Nov 15 00:00:00 UTC 2019

HnRNP-F promotes cell proliferation by regulating TPX2 in bladder cancer.

American journal of translational research

Li F,Su M,Zhao H,Xie W,Cao S,Xu Y,Chen W,Wang L,Hou L,Tan W

Thu Oct 01 00:00:00 UTC 2020

Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Yap JLY,Tai YK,Fröhlich J,Fong CHH,Yin JN,Foo ZL,Ramanan S,Beyer C,Toh SJ,Casarosa M,Bharathy N,Kala MP,Egli M,Taneja R,Lee CN,Franco-Obregón A

Fri Nov 01 00:00:00 UTC 2019

Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells.

BMC complementary and alternative medicine

Que Z,Zhou Z,Luo B,Dong C,Jiang Y,Li H,Tian J

Wed Aug 07 00:00:00 UTC 2019

Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.

Nature communications

Su D,Zhang D,Jin J,Ying L,Han M,Chen K,Li B,Wu J,Xie Z,Zhang F,Lin Y,Cheng G,Li JY,Huang M,Wang J,Wang K,Zhang J,Li F,Xiong L,Futreal A,Mao W

Thu Nov 07 00:00:00 UTC 2019

Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).

Cancer cell international

Zhang C,Wang B,Wang X,Sheng X,Cui Y

Tue Apr 12 00:00:00 UTC 2022

Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.

Aging

Li Y,Kong R,Chen H,Zhao Z,Li L,Li J,Hu J,Zhang G,Pan S,Wang Y,Wang G,Chen H,Sun B

Sun Jul 21 00:00:00 UTC 2019

REG4 is an indicator for KRAS mutant lung adenocarcinoma with TTF-1 low expression.

Journal of cancer research and clinical oncology

Sun S,Hu Z,Huang S,Ye X,Wang J,Chang J,Wu X,Wang Q,Zhang L,Hu X,Yu H

Sun Sep 01 00:00:00 UTC 2019

Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.

Journal of cellular physiology

Fang C,He W,Xu T,Dai J,Xu L,Sun F

Wed May 01 00:00:00 UTC 2019

Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.

RSC advances

Tian Y,He J,Liu N,Huang D,Liu Z,Yang Y,Chen J,Zhao B,Zhao S,Liang B

Wed Jun 13 00:00:00 UTC 2018

Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.

RSC advances

Tian Y,He J,Liu N,Huang D,Liu Z,Yang Y,Chen J,Zhao B,Zhao S,Liang B

Wed Jun 13 00:00:00 UTC 2018

The natural agent rhein induces β-catenin degradation and tumour growth arrest.

Journal of cellular and molecular medicine

Liu S,Wang J,Shao T,Song P,Kong Q,Hua H,Luo T,Jiang Y

Mon Jan 01 00:00:00 UTC 2018

The natural agent rhein induces β-catenin degradation and tumour growth arrest.

Journal of cellular and molecular medicine

Liu S,Wang J,Shao T,Song P,Kong Q,Hua H,Luo T,Jiang Y

Mon Jan 01 00:00:00 UTC 2018

lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.

Molecular carcinogenesis

Du Y,Wang L,Chen S,Liu Y,Zhao Y

Sat Sep 01 00:00:00 UTC 2018

Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.

Journal of agricultural and food chemistry

Han B,Jiang P,Liu W,Xu H,Li Y,Li Z,Ma H,Yu Y,Li X,Ye X

Wed Jun 20 00:00:00 UTC 2018

Modulation of cyclins and p53 in mesangial cell proliferation and apoptosis during Habu nephritis.

Clinical and experimental nephrology

Lu Y,Wen J,Chen D,Wu L,Li Q,Xie Y,Wu D,Liu X,Chen X

Fri Apr 01 00:00:00 UTC 2016

KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X

Mon Feb 15 00:00:00 UTC 2016

KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X

Mon Feb 15 00:00:00 UTC 2016

KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X

Mon Feb 15 00:00:00 UTC 2016

KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.

American journal of physiology. Lung cellular and molecular physiology

Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X

Mon Feb 15 00:00:00 UTC 2016

Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.

Oncotarget

Cao N,Ma X,Guo Z,Zheng Y,Geng S,Meng M,Du Z,Lin H,Duan Y,Du G

Tue Sep 20 00:00:00 UTC 2016

GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy.

Oncotarget

Zhang Q,Zhuang J,Deng Y,Zhao X,Tang B,Yao D,Zhao W,Chang C,Lu Q,Chen W,Zhang S,Ji C,Cao L,Guo H

Tue Oct 13 00:00:00 UTC 2015

FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.

Cancer biology & therapy

Peng X,Luo Z,Kang Q,Deng D,Wang Q,Peng H,Wang S,Wei Z

Tue Jun 14 00:00:00 UTC 2016

Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.

Proteomics

Hao L,Zhou X,Liu S,Sun M,Song Y,Du S,Sun B,Guo C,Gong L,Hu J,Guan H,Shao S

Tue Sep 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; CCND1 protein; cDNA; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD-1; PRAD1 oncogene

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Gene Aliases: AI327039; bcl-1; BCL1; CCND1; cD1; CycD1; Cyl-1; D11S287E; PRAD1; U21B31

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UniProt ID: (Human) P24385, (Rat) P39948, (Mouse) P25322

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Entrez Gene ID: (Human) 595, (Rat) 58919, (Mouse) 12443

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Function(s)

transcription corepressor activity protein kinase activity protein binding transcription factor binding cyclin-dependent protein serine/threonine kinase regulator activity enzyme binding protein kinase binding protein complex binding histone deacetylase binding proline-rich region binding kinase activity

Process(es)

G1/S transition of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter re-entry into mitotic cell cycle liver development positive regulation of protein phosphorylation transcription, DNA-templated protein phosphorylation cellular response to DNA damage stimulus lactation positive regulation of cell proliferation response to organic substance response to iron ion response to X-ray response to organonitrogen compound positive regulation of G2/M transition of mitotic cell cycle response to organic cyclic compound Wnt signaling pathway negative regulation of Wnt signaling pathway negative regulation of epithelial cell differentiation endoplasmic reticulum unfolded protein response organ regeneration mitotic G1 DNA damage checkpoint response to magnesium ion response to estradiol response to vitamin E Leydig cell differentiation mammary gland epithelial cell proliferation positive regulation of mammary gland epithelial cell proliferation response to drug response to estrogen fat cell differentiation response to ethanol positive regulation of cyclin-dependent protein serine/threonine kinase activity regulation of protein kinase activity response to steroid hormone cell division response to glucocorticoid response to corticosterone response to calcium ion regulation of cell cycle canonical Wnt signaling pathway mammary gland alveolus development response to UV-A negative regulation of cell cycle arrest cellular response to organic substance regulation of G1/S transition of mitotic cell cycle response to leptin positive regulation of cell cycle liver regeneration regulation of transcription, DNA-templated cell cycle

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Cyclin D1 Polyclonal Antibody

Cyclin D1 Antibody (26939-1-AP) in ICC/IF

Product Details

26939-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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